Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jacqueline E. Mann"'
Autor:
Anna M. Schmoker, Samuel A. Barritt, Marion E. Weir, Jacqueline E. Mann, Tyler C. Hogan, Bryan A. Ballif, Paula B. Deming
Publikováno v:
Proteomes, Vol 6, Iss 4, p 37 (2018)
The cAMP-dependent protein kinase A (PKA) is a serine/threonine kinase involved in many fundamental cellular processes, including migration and proliferation. Recently, we found that the Src family kinase Fyn phosphorylates the catalytic subunit of P
Externí odkaz:
https://doaj.org/article/7d6b03d3fa484afca32d52efd6d993a5
Autor:
Clara Abraham, Marie E Robert, Harriet M Kluger, Lilach Aizenbud, Kevan C Herold, Matthew R Austin, Jacqueline E Mann, Ross D Merkin, Liliana Lucca, Badr Al Bawardy, Khadir Raddassi, Nikhil S Joshi, David A Hafler
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 8 (2023)
Immune checkpoint inhibitors (ICIs) are increasingly being used to manage multiple tumor types. Unfortunately, immune-related adverse events affect up to 60% of recipients, often leading to treatment discontinuation in settings where few alternative
Externí odkaz:
https://doaj.org/article/9756494ca35a45cda13db78f98f7441b
Autor:
Joshua D, Smith, Emily L, Bellile, Susan E, Ellsperman, Molly E, Heft-Neal, Jacqueline E, Mann, Andrew C, Birkeland, Rebecca C, Hoesli, Paul L, Swiecicki, Francis P, Worden, Caitlin, Schonewolf, Jennifer L, Shah, Michelle L, Mierzwa, Andrew J, Rosko, Chaz L, Stucken, Steven B, Chinn, Andrew G, Shuman, Keith A, Casper, Kelly M, Malloy, Mark E P, Prince, Gregory T, Wolf, Dafydd G, Thomas, Jonathan B, McHugh, J, Chad Brenner, Matthew E, Spector
Publikováno v:
Oral oncology. 135
In an evolving era of immunotherapeutic options for persistent or recurrent laryngeal squamous cell carcinoma (LSCC), there is a need for improved biomarkers of treatment response and survival to inform optimal treatment selection and prognostication
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::988a24982dc44e590e35a78d7b2fdcad
https://pubmed.ncbi.nlm.nih.gov/36323071
https://pubmed.ncbi.nlm.nih.gov/36323071
Autor:
Jacqueline E. Mann, Liliana Lucca, Matthew Austin, Ross D. Merkin, Lilach Aizenbud, Kevan Herold, Marie Robert, Harriet M. Kluger
Publikováno v:
Cancer Research. 83:2268-2268
Background: Immune checkpoint inhibition is an increasingly popular strategy for the management of numerous malignancies. Unfortunately, severe inflammatory toxicities affect up to 60% of patients, often leading to treatment discontinuation in settin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71a8e3ea619c55e996fa50c22235b31a
https://doi.org/10.1158/1538-7445.am2023-2268
https://doi.org/10.1158/1538-7445.am2023-2268
Autor:
Jingyi Zhai, Jacqueline E. Mann, Aditi Kulkarni, Elizabeth Gensterblum-Miller, Isabel R Murray, J. Chad Brenner, Megan L. Ludwig, Erin B Scheftz, Hui Jiang
Publikováno v:
Cancers
Volume 13
Issue 19
Cancers, Vol 13, Iss 4782, p 4782 (2021)
Volume 13
Issue 19
Cancers, Vol 13, Iss 4782, p 4782 (2021)
Simple Summary Tumors use immunosuppressive signals to evade detection by the immune system. While recurrent and metastatic head and neck squamous cell carcinoma has historically carried a poor prognosis, therapies targeting the immunosuppressive PD1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::416fc0420f140df7fc9a64bf54f49be5
Autor:
Nicole L. Michmerhuizen, J. Chad Brenner, Susan K. Foltin, Andrew G. Shuman, Matthew E. Spector, Jacqueline E. Mann, Thomas E. Carey, Megan L. Ludwig, Hui Jiang, Aditi Kulkarni, Samantha N. Devenport, Brittany M. Jewell, Rebecca C. Hoesli, Andrew C. Birkeland
Publikováno v:
Oral Oncology. 87:144-151
Objectives We sought to describe the genetic complexity of 14 UM-SCC oral cavity cancer cell lines that have remained uncharacterized despite being used as model systems for decades. Materials and Methods We performed exome sequencing on 14 oral cavi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffd90500de1a3a1128da2805922eb729
https://doi.org/10.1016/j.oraloncology.2018.10.031
https://doi.org/10.1016/j.oraloncology.2018.10.031
Autor:
M E Heft Neal, Catherine T. Haring, Paul L. Swiecicki, M.E. Spector, J.C. Brenner, Jacqueline E. Mann
Publikováno v:
J Cancer Metastasis Treat
Unresectable recurrent or metastatic head and neck cancer is an incurable disease with survival of approximately 12 months. Head and neck tumors exhibit numerous derangements in the tumor microenvironment that aid in immune evasion and may serve as t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d888743570fd4d309d370d4e4c919e8
https://pubmed.ncbi.nlm.nih.gov/32661502
https://pubmed.ncbi.nlm.nih.gov/32661502
Autor:
Nicole L. Michmerhuizen, N Jawad, T R Vandenberg, Megan L. Ludwig, M.E. Spector, J.C. Brenner, Andrew G. Shuman, Rebecca C. Hoesli, Michelle Mierzwa, Jacqueline E. Mann, Samantha N. Devenport, Chloe Matovina
Publikováno v:
Journal of Cancer
Immunotherapy is becoming an accepted treatment modality for many patients with cancer and is now approved for use in platinum-refractory recurrent or metastatic head and neck squamous cell carcinoma (HNSCC). Despite these successes, a minority of pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cd31e91248aea8cc28ed55054ca75dc
https://doi.org/10.7150/jca.17547
https://doi.org/10.7150/jca.17547
Autor:
Andrew C. Birkeland, Megan L. Ludwig, Hui Jiang, Julia Eisenberg, Judy Kafelghazal, J. Chad Brenner, Matthew E. Spector, Jacqueline E. Mann, Thomas E. Carey, Aditi Kulkarni, Brittany M. Jewell
Publikováno v:
Head & neck, vol 41, iss 9
Head Neck
Head Neck
Background Laryngeal squamous cell carcinomas (LSCCs) have a high risk of recurrence and poor prognosis. Patient-derived cancer cell lines remain important preclinical models for advancement of new therapeutic strategies, and comprehensive characteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2437706dd247357e569f40fed28f510
https://escholarship.org/uc/item/57p9f9nc
https://escholarship.org/uc/item/57p9f9nc
Autor:
Jonathan B. McHugh, Emily Bellile, Gregory T. Wolf, Keith A. Casper, Scott A. McLean, Paul L. Swiecicki, Joshua D. Smith, Kelly M. Malloy, Carol R. Bradford, Jacqueline E. Mann, Andrew G. Shuman, Jeffery Moyer, J. Chad Brenner, Thomas E. Carey, Andrew C. Birkeland, Matthew E. Spector, Steven B. Chinn, Michelle Mierzwa, Mark E. Prince
Publikováno v:
Cancer immunology, immunotherapy : CII, vol 68, iss 2
BACKGROUND: Recurrent laryngeal squamous cell carcinomas (LSCCs) are associated with poor outcomes, without reliable biomarkers to identify patients who may benefit from adjuvant therapies. Given the emergence of tumor infiltrating lymphocytes (TIL)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4369fcdbd95f3d429b4f94d44a19e355
https://escholarship.org/uc/item/6vm284d0
https://escholarship.org/uc/item/6vm284d0