Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jacqueline Dumats"'
Publikováno v:
European Journal of Inorganic Chemistry. 2001:471-479
The complexation of FeIII by new tetradentate and pentadentate aminocarboxylate chelators, designed to protect cells against iron-catalysed oxidative damage, was investigated. Ferric iron complexes of N,N′-bis(3,4,5-trimethoxybenzyl)ethylenediamine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20c1e744ac7843d53e62843ff5113741
https://doi.org/10.1002/1099-0682(200102)2001:2<471::aid-ejic471>3.0.co
https://doi.org/10.1002/1099-0682(200102)2001:2<471::aid-ejic471>3.0.co
Publikováno v:
Journal of Medicinal Chemistry. 43:1418-1421
N,N'-Bis(3,4,5-trimethoxybenzyl)ethylenediamine-N,N'-diacetic acid (1) was recently described as a new type of iron chelator for protection against oxidative damage. It has a low affinity for iron, but the corresponding iron complex undergoes a site-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69de5f1007d096e0ea00770a9f81e48a
https://doi.org/10.1021/jm9911635
https://doi.org/10.1021/jm9911635
Autor:
Jacqueline Dumats, Marc Fontecave, Georges Hussler, Michel Seite, Stéphane Ménage, Geneviève Chottard, Isabelle Gautier Luneau, Jean-Baptiste Galey
Publikováno v:
Journal of the American Chemical Society. 120:13370-13382
Chemical models of active sites of diiron oxo proteins have been synthesized. The polydendate ligands are EDTA derivatives which provide a balanced supply of nitrogen atoms and carboxylate groups t...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18c35552c8dafb64f8a01e3c17509df8
https://doi.org/10.1021/ja981123a
https://doi.org/10.1021/ja981123a
Publikováno v:
Free Radical Research. 22:67-86
During oxidative stress, iron traces are supposed to be released from normal storage sites and to catalyse oxidative damage by Fenton-type reactions. This type of damage is difficult to prevent in vivo except by the use of strong iron chelators such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17c4580088d5d9c850ee1dbc00cdebf4
https://doi.org/10.3109/10715769509147529
https://doi.org/10.3109/10715769509147529
Autor:
Herve Plessix, Laurence Le Capitaine, Orazio Cantoni, Giovanni Bracciolli, Jacqueline Dumats, Sylvie Genard, Jean-Baptiste Galey, Patrick Pichaud, Odile Destree, Johann Marché, Liliana Brambilla
Publikováno v:
Free radical biologymedicine. 25(8)
A new series of iron chelators designed to protect tissues against iron-catalysed oxidative damage is described. These compounds are aminocarboxylate derivatives bearing pendant aromatic groups. They were designed to have a relatively low affinity fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9480c381f43184ae716cc7b574f069d
https://pubmed.ncbi.nlm.nih.gov/9840732
https://pubmed.ncbi.nlm.nih.gov/9840732
Autor:
Bona Fernandez, Jacqueline Dumats, Sylvie Genard, Gilles Barre, Irena Beck, Laurent Marrot, Michel Hocquaux, Philippe Cctroux, Odile Destree, Michel Seité, Georges Hussler, Jean-Baptiste Galey, Patrick Pichaud
Publikováno v:
Biochemical pharmacology. 51(2)
N,N′-bis-(3,4,5-trimethoxybenzyl) ethylenediamine N,N′-diacetic acid dihydrochloride (OR10141) is a member of a recently described series of “oxidative stress activatable iron chelators”. These chelators have a relatively low affinity for iro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdecbe145dbbe360750b97dcd998e65e
https://pubmed.ncbi.nlm.nih.gov/8615878
https://pubmed.ncbi.nlm.nih.gov/8615878