Výsledky vyhledávání - "Jacqueline Courant"

N-Pyridinyl-indole-3-(alkyl)carboxamides and derivatives as potential systemic and topical inflammation inhibitors

Autor: Muriel Duflos, Nicole Grimaud, Jean-Yves Petit, Jacqueline Courant, Guillaume LeBaut, Jacques Brelet, Marie-Renée Nourrisson

Publikováno v: European Journal of Medicinal Chemistry. 36:545-553

N-substituted-(indol-3-yl)carboxamides 10–15 and alkanamides 16–18 were prepared starting from the corresponding acids and submitted to screening for evaluation of their anti-inflammatory activity. None of the considered carboxamides exhibited si

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc8b856701e3b379076eb0a88b2e399b
https://doi.org/10.1016/s0223-5234(01)01242-9

Zobrazit plný text záznamu

6-Amino-2,4-lutidine carboxamides: α-aminoamide derivatives as systemic and topical inflammation inhibitors

Autor: Nicole Grimaud, Pierre Renard, Daniel-Henri Caignard, Dominique Manechez, Guillaume Le Baut, Jacqueline Courant, Muriel Duflos

Publikováno v: European Journal of Medicinal Chemistry. 33:635-645

The development of new potential anti-inflammatory compounds resulting from the incorporation of α-aminoacid residues into 6-amino-2,4-lutidine afforded (N-protected) aminoamides with interesting inhibitory activity. Out of 28 tested compounds, 10 (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e3673ce164157a6aeb62ba3ca0d1bfd1
https://doi.org/10.1016/s0223-5234(98)80022-6

Zobrazit plný text záznamu

Non-carboxylic antiinflammatory compounds. III. N-(4,6-Dimethylpyridin-2-yl)arylcarboxamides and arylthiocarboxamides acting as brain edema inhibitors

Autor: J. Y. Petit, L. Welin, G. Le Baut, Jacqueline Courant, N. Grimaud, Sylvie Robert-Piessard, François Lang, J. M. Robert, B. Robert

Publikováno v: European Journal of Medicinal Chemistry. 30:915-924

Summary Pharmacomodulation of the non-carboxylic NSAID N -(4,6-dimethylpyridin-2-yl)benzamide 1 led to the synthesis of structurally related furan, thiophene and pyrrole carboxamides 3–14 . The derivatives benzenethiocarboxamides 15–18 and hetero

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ad5eb1d3260b21e762b15a94b0c7701c
https://doi.org/10.1016/0223-5234(96)88310-3

Zobrazit plný text záznamu

Structure du N-phényltroloxamide et du N-phényltroloxthioamide, inhibiteurs de leucotriènes

Autor: J. M. Cense, N. Rodier, Jacqueline Courant, G. Le Baut, Jean-Paul Babingui

Publikováno v: Acta Crystallographica Section C Crystal Structure Communications. 50:960-963

Both compounds [N-phenyl-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxamide (N-phenyltroloxamide), C 20 H 23 NO 3 , and N-phenyl-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carbothioxamide (N-phenyltroloxthioamide), C 20 H 23 NO 2 S] hav

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bcb76aacb5d9ff8679f96d59dc34f6a3
https://doi.org/10.1107/s0108270193010352

Zobrazit plný text záznamu

3-Sulfure de 3-mercapto-5,7-diméthyl-2-phényl-3H-[1,4,2]diazaphospholo[1,5-a]pyridinium

Autor: J. M. Robert, G. Le Baut, Sylvie Robert-Piessard, Jacqueline Courant, N. Rodier, J. M. Cense

Publikováno v: Acta Crystallographica Section C Crystal Structure Communications. 50:810-813

The entire molecule of 5,7-dimethyl-2-phenyl-3-thioxo-3H-[1,4,2]diazaphospholo[1,5-a]pyridinium-3thiolate, C 14 H 13 N 2 PS 2 , with the exception of the two S atoms, is approximately planar. The π electrons of the N(7)-C(8) bond are partially conju

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3b5c7f298e8bc057254be9613ac02d9c
https://doi.org/10.1107/s0108270193010327

Zobrazit plný text záznamu

Synthesis and antiallergic activity of N-(pyridin-2-yl)-3-(piperazin-1-yl) propanamides

Autor: C. Venco, Jacqueline Courant, D. Leblois, E. Panconi, G. Le Baut

Publikováno v: European Journal of Medicinal Chemistry. 28:821-824

A series of 6 new N -(pyridin-2-yl)-3-(piperazin-1-yl)propanamides were synthesized from the corresponding N -pyridinylpropenamides to determine potential antiallergic activity as assayed in vivo by the passive cutaneous anaphylaxis test. The IC 50 o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3d47e056fb6eda4c277613d79b0ede74
https://doi.org/10.1016/0223-5234(93)90117-w

Zobrazit plný text záznamu

ChemInform Abstract: Synthesis and Antiallergic Activity of N-(Pyridin-2-yl)-3-(piperazin-1- yl)propanamides

Autor: E. Panconi, C. Venco, Jacqueline Courant, D. Leblois, G. Le Baut

Publikováno v: ChemInform. 25

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b9adef3266787e3c5274667531a8d16b
https://doi.org/10.1002/chin.199407196

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání