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pro vyhledávání: '"Jacqueline Chapron"'
Publikováno v:
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Neuronal networks in the mouse spinal cord express serotonin (5-HT)-induced rhythmic motor activity at early developmental stages (embryonic day (E) 12.5). Later in development, by post-natal day (P) 10, the 5-HT-evoked rhythmic motor activity mature
Publikováno v:
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Spontaneous synchronous rhythmic activities are a common feature of immature neuronal networks. Although the mechanisms underlying such activities have been studied extensively, whether they might be controlled by modulatory information remains quest
Autor:
S. Tzartos, B. Eymard, Jacqueline Chapron, S. C. de., K. Poulas, F. Fabre, Jeanine Koenig, La Porte, E. Chaubourt
Publikováno v:
European Journal of Neuroscience. 10:1631-1643
To study a step of the very complex processes of the formation of the neuromuscular junction (NMJ), we have analysed the clustering of acetylcholine receptors (AChR) and acetylcholinesterase (AChE) in myotubes cultured in various conditions. On the s
Publikováno v:
European Journal of Neuroscience. 9:260-270
Using a monoclonal antibody (6.17) directed against a Schwann antigen, we have shown that Schwann cells synthesize a molecule implicated in a change of expression of synaptic cholinesterases, AChE and BChE, during muscle differentiation. In vitro, du
Autor:
Jacqueline Chapron, Jeanine Koenig, Jean-Luc Ridet, Alain Privat, Gérard Alonso, Norbert Chauvet
Publikováno v:
Cell and Tissue Research. 283:39-49
A specific monoclonal antiserum (Mab 6.17) inducing a strong immunostaining of the neuromuscular junction has been used to detect the possible occurrence of the corresponding antigen throughout the intact or lesioned central nervous system of adult r
Autor:
Bruno Eymard, Jacqueline Chapron, Jeanine Koenig, Pierre Courbin, Fatima Ragueh, Sabine de la Porte
Publikováno v:
Journal of the Neurological Sciences. 117:92-102
Myasthenia gravis (MG) is mediated by circulating antibodies directed against acetylcholine receptor (AChR) but the antibody titre is poorly correlated with the clinical severity of the disease. We analysed acetylcholinesterase (AChE) activity, molec
Publikováno v:
Neuroscience Letters. 121:21-24
Cultures of spinal cord neurons and cocultures of rat embryo neurons and muscle cells have been studied in the presence of tetanus toxin (TT) at a concentration of 40 μg/ml of medium. TT strongly stimulated neurite outgrowth, notably branching from
Publikováno v:
Journal of physiology, Paris. 92(3-4)
Synapses obtained in vitro in a system of co-culture of muscle cells and neurons are of embryonic type. We prepared a monoclonal antibody (6.17) which recognizes a molecule synthesized by Schwann cells and used it to show that the main characteristic
Autor:
Jacqueline Chapron, Jeanine Koenig
Publikováno v:
Neuromuscular disorders : NMD. 3(5-6)
This work compares the efficacy of varying the concentrations of cryoprotectants when freezing samples of rat muscles for later use in tissue culture. The best yields were obtained with DMSO associated with glycerol and sucrose; before plating, the b
Autor:
Jacqueline Chapron, Philippe Méléard, Marie Laure Lascombe, Michel Grouselle, Jeanine Koenig, D. Georgescauld
Publikováno v:
Pflugers Archiv : European journal of physiology. 418(1-2)
Rat myotubes have a resting [Ca2+]i of about 82 nM. Myotubes 3-5 days old (quiescent myotubes) display electrically induced and spontaneous transients in the intracellular concentration of free Ca2+ ions ([Ca2+]i) uncoupled to any detectable contract