Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Jacqueline Bayliss"'
Autor:
Hamzeh Karimkhanloo, Stacey N. Keenan, Jacqueline Bayliss, William De Nardo, Paula M. Miotto, Camille J. Devereux, Shuai Nie, Nicholas A. Williamson, Andrew Ryan, Matthew J. Watt, Magdalene K. Montgomery
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Non-alcoholic steatohepatitis (NASH), characterized as the joint presence of steatosis, hepatocellular ballooning and lobular inflammation, and liver fibrosis are strong contributors to liver-related and overall mortality. Despite the high g
Externí odkaz:
https://doaj.org/article/0f81f952cf38469ca8daa7ce5886971f
Autor:
Magdalene K. Montgomery, Jacqueline Bayliss, Shuai Nie, William De Nardo, Stacey N. Keenan, Paula M. Miotto, Hamzeh Karimkhanloo, Cheng Huang, Ralf B. Schittenhelm, Anthony S. Don, Andrew Ryan, Nicholas A. Williamson, Geraldine J. Ooi, Wendy A. Brown, Paul R. Burton, Benjamin L. Parker, Matthew J. Watt
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Non-alcoholic steatohepatitis (NASH) and type 2 diabetes are closely linked, but the connecting pathophysiological mechanisms are incompletely understood. Here the authors identify arylsulfatase A as a NASH-induced hepatokine that inhibits hepatic ly
Externí odkaz:
https://doaj.org/article/0e3d36630f204b8aa3e526d0e0913eb1
Autor:
William De Nardo, Paula M. Miotto, Jacqueline Bayliss, Shuai Nie, Stacey N. Keenan, Magdalene K. Montgomery, Matthew J. Watt
Publikováno v:
Molecular Metabolism, Vol 60, Iss , Pp 101491- (2022)
Objective: Non-alcoholic fatty liver disease (NAFLD) is linked to impaired lipid metabolism and systemic insulin resistance, which is partly mediated by altered secretion of liver proteins known as hepatokines. Regular physical activity can resolve N
Externí odkaz:
https://doaj.org/article/703f3df833344ba2a9037ed17054464f
Autor:
Jacqueline Bayliss, Geraldine J. Ooi, William De Nardo, Yazmin Johari Halim Shah, Magdalene K. Montgomery, Catriona McLean, William Kemp, Stuart K. Roberts, Wendy A. Brown, Paul R. Burton, Matthew J. Watt
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Ectodysplasin A (EDA) was recently identified as a liver-secreted protein that is increased in the liver and plasma of obese mice and causes skeletal muscle insulin resistance. We assessed if liver and plasma EDA is associated with worsening non-alco
Externí odkaz:
https://doaj.org/article/25a873eb0dba42f9920526140db6b0cf
Autor:
Camille J. Devereux, Jacqueline Bayliss, Stacey N. Keenan, Magdalene K. Montgomery, Matthew J. Watt
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 324:E187-E198
Dysregulation of hepatic lipid metabolism is a hallmark of nonalcoholic fatty liver disease. Here, we show that dual inhibition of the de novo lipogenesis enzyme, ACC, and hepatic deletion of the fatty acid transporter, CD36, was ineffective for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::987c0a9ff0901501938860c7cb047bd1
https://doi.org/10.1152/ajpendo.00161.2022
https://doi.org/10.1152/ajpendo.00161.2022
Autor:
Magdalene K. Montgomery, Jacqueline Bayliss, Shuai Nie, William de Nardo, Stacey N. Keenan, Marziyeh Anari, Amanuiel Z. Taddese, Nicholas A. Williamson, Geraldine J. Ooi, Wendy A. Brown, Paul R. Burton, Paul Gregorevic, Craig A. Goodman, Kevin I. Watt, Matthew J. Watt
Publikováno v:
Diabetes. 72:715-727
Non-alcoholic fatty liver disease (NAFLD) and impaired glycaemic control are closely linked, however, the pathophysiological mechanisms underpinning this bidirectional relationship remain unresolved. The high secretory capacity of the liver and impai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19fb2002fab7eac62bf27db230f50f5d
https://doi.org/10.2337/db22-0590
https://doi.org/10.2337/db22-0590
Autor:
Jacqueline Bayliss, Magdalene K. Montgomery, Shuai Nie, Matthew J. Watt, Nicholas A. Williamson, Amanuiel Z. Taddese
Publikováno v:
The FASEB Journal. 35
Hexosaminidase A (HexA), a heterodimer consisting of HEXA and HEXB, converts the ganglioside sphingolipid GM2 to GM3 by removing a terminal N-acetyl-d-galactosamine. HexA enzyme deficiency in humans leads to GM2 accumulation in cells, particularly in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c21867d09cd28fb12d69176e10bdff6
https://doi.org/10.1096/fj.202101186r
https://doi.org/10.1096/fj.202101186r
Autor:
Magdalene K, Montgomery, Jacqueline, Bayliss, Shuai, Nie, William, De Nardo, Stacey N, Keenan, Paula M, Miotto, Hamzeh, Karimkhanloo, Cheng, Huang, Ralf B, Schittenhelm, Anthony S, Don, Andrew, Ryan, Nicholas A, Williamson, Geraldine J, Ooi, Wendy A, Brown, Paul R, Burton, Benjamin L, Parker, Matthew J, Watt
Publikováno v:
Nature communications. 13(1)
Non-alcoholic steatohepatitis (NASH) and type 2 diabetes are closely linked, yet the pathophysiological mechanisms underpinning this bidirectional relationship remain unresolved. Using proteomic approaches, we interrogate hepatocyte protein secretion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::617d69f6a256bcc1dbedd5e01ee36dec
https://pubmed.ncbi.nlm.nih.gov/35273160
https://pubmed.ncbi.nlm.nih.gov/35273160
Autor:
Magdalene K. Montgomery, Wendy A. Brown, Yazmin Johari Halim Shah, Matthew J. Watt, Paul Burton, Jacqueline Bayliss, William De Nardo, William Kemp, Stuart K. Roberts, Geraldine J. Ooi, Catriona McLean
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Frontiers in Endocrinology
Frontiers in Endocrinology
Ectodysplasin A (EDA) was recently identified as a liver-secreted protein that is increased in the liver and plasma of obese mice and causes skeletal muscle insulin resistance. We assessed if liver and plasma EDA is associated with worsening non-alco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a17ada2f21662671d35dd55f1d98777
https://pubmed.ncbi.nlm.nih.gov/33746906
https://pubmed.ncbi.nlm.nih.gov/33746906
Autor:
Magdalene K. Montgomery, Camille Devereux, Matthew J. Watt, Jacqueline Bayliss, Cheng Huang, David Roberts, Scott L. Townley, Dorit Samocha-Bonet, Ayenachew Bezawork-Geleta, Ruth C. R. Meex, Ralf B. Schittenhelm, Andrew Ryan, Gregory R. Steinberg, Trevor J. Biden, Luke A. Selth
Publikováno v:
Science Translational Medicine, 12(559):8048. American Association for the Advancement of Science
Intertissue communication is a fundamental feature of metabolic regulation, and the liver is central to this process. We have identified sparc-related modular calcium-binding protein 1 (SMOC1) as a glucose-responsive hepatokine and regulator of gluco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a783e3199ac1dd010bb5fa13902d4cfc
https://cris.maastrichtuniversity.nl/en/publications/4ff0da9e-6b61-4c36-9abf-fbb82385675e
https://cris.maastrichtuniversity.nl/en/publications/4ff0da9e-6b61-4c36-9abf-fbb82385675e