Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jacqueline A. Walisser"'
Autor:
Mariko Izumo, Martina Pejchal, Andrew C Schook, Ryan P Lange, Jacqueline A Walisser, Takashi R Sato, Xiaozhong Wang, Christopher A Bradfield, Joseph S Takahashi
Publikováno v:
eLife, Vol 3 (2014)
In order to assess the contribution of a central clock in the hypothalamic suprachiasmatic nucleus (SCN) to circadian behavior and the organization of peripheral clocks, we generated forebrain/SCN-specific Bmal1 knockout mice by using floxed Bmal1 an
Externí odkaz:
https://doaj.org/article/82735a2b211a49ad9aa07026cc68c714
Autor:
R. Dustan Sarazan, Jennifer Doyle, Jennifer B. Pierson, Scott W. Mittelstadt, Sean Ottinger, Michael K. Pugsley, Jacqueline A. Walisser, Michael J. Engwall, Eric I. Rossman, Alan Y. Chiang, John Koerner, Peter Hoffmann, Brian Guth, Jean-Michel Guillon
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 75:70-90
Introduction Drug-induced effects on the cardiovascular system remain a major cause of drug attrition. While hemodynamic (blood pressure (BP) and heart rate (HR)) and electrophysiological methods have been used in testing drug safety for years, anima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d7f991b9260ffae25edfd6e45af7db7
Autor:
Michael Taschwer, Kenneth S. Latimer, Andrea Z. Mitchell, Jacqueline A. Walisser, Alok K. Sharma, Mark A. Osinski, Andrew J. Bills
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 68:52-61
Introduction Electrocardiogram (ECG) signals in safety pharmacology studies are generally collected via subcutaneous or epicardial leads. Subcutaneous placement is an easier procedure, but signals often contain artifacts. Epicardial leads offer impro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0d32a6db60253ba8d02054b3821a79e
https://doi.org/10.1016/j.vascn.2013.04.001
https://doi.org/10.1016/j.vascn.2013.04.001
Autor:
Jacqueline A. Walisser, Christopher A. Bradfield, Gregory D. Kennedy, Susan M. Moran, Manabu Nukaya
Publikováno v:
Toxicological Sciences. 118:554-563
The aryl hydrocarbon receptor (AHR) plays a central role in the toxic responses to halogenated dibenzo-p-dioxins (“dioxins”), in the metabolic adaptation to polycyclic aromatic hydrocarbons, and in the development of the mature vascular system. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c2db119ff59290e2d105fb75804201c
https://doi.org/10.1093/toxsci/kfq305
https://doi.org/10.1093/toxsci/kfq305
Autor:
Susan M. Moran, E.W.N. Glover, Jacqueline A. Walisser, Christopher A. Bradfield, Maureen K. Bunger, Erin L. Hsu, Garet P. Lahvis
Publikováno v:
Toxicological Sciences
The aryl hydrocarbon receptor (AHR) is known for its role in the adaptive and toxic responses to a large number of environmental contaminants, as well as its role in hepatovascular development. The classical AHR pathway involves ligand binding, nucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::466c218a95b2ef0b32fbe387480e3c95
https://doi.org/10.1093/toxsci/kfn149
https://doi.org/10.1093/toxsci/kfn149
Publikováno v:
Proceedings of the National Academy of Sciences. 102:17858-17863
The aryl hydrocarbon receptor (AHR) plays a role in three areas of biology that include the adaptive metabolism of xenobiotics, the toxic responses associated with exposure to 2,3,7,8-tetrachlorodibenzo- p -dioxin (dioxin), and vascular remodeling of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6824b307f9ef32212a28fcf150103a4d
https://doi.org/10.1073/pnas.0504757102
https://doi.org/10.1073/pnas.0504757102
Autor:
Erinn B. Rankin, Christopher A. Bradfield, Debra F. Higgins, Volker H. Haase, Jacqueline A. Walisser, Randall S. Johnson
Publikováno v:
Molecular and Cellular Biology. 25:3163-3172
Germ line mutations in the VHL tumor suppressor gene result in von Hippel-Lindau (VHL) disease, a familial tumor syndrome that predisposes affected patients to the development of highly vascularized neoplasms. These include hemangioblastomas of the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa47489d3ef4ef8aa5f1e5f637b09fbb
https://doi.org/10.1128/mcb.25.8.3163-3172.2005
https://doi.org/10.1128/mcb.25.8.3163-3172.2005
Autor:
Stevan B. Jovanovich, Gina M. Zastrow, Russell S. Thomas, Jacqueline A. Walisser, Kevin R. Hayes, Sharon Penn, David R. Rank, Mark Craven, Christopher A. Bradfield, Aaron L. Vollrath, Brian J. McMillan, Janardan K. Reddy
Publikováno v:
Molecular Pharmacology. 67:1360-1368
Transcriptional profiling via microarrays holds great promise for toxicant classification and hazard prediction. Unfortunately, the use of different microarray platforms, protocols, and informatics often hinders the meaningful comparison of transcrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::985d9229dd6b00b64576d66dbbeaf93e
https://doi.org/10.1124/mol.104.009175
https://doi.org/10.1124/mol.104.009175
Publikováno v:
Proceedings of the National Academy of Sciences. 101:16677-16682
The aryl hydrocarbon receptor (AHR) is commonly known for its role in the adaptive metabolism of xenobiotics and in the toxic events that follow exposure to 2,3,7,8-tetrachlorodibenzo- p -dioxin (dioxin). Previously, we have demonstrated that the AHR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e04fa5ea92340af630de43c74e22166
https://doi.org/10.1073/pnas.0404379101
https://doi.org/10.1073/pnas.0404379101
Autor:
E.W.N. Glover, Christopher A. Bradfield, Eric B. Harstad, Maureen K. Bunger, Jacqueline A. Walisser
Publikováno v:
Journal of Biological Chemistry. 279:16326-16331
The Ah receptor nuclear translocator (ARNT) is the dimeric partner of hypoxia-inducible factors and thus plays a pivotal role in cellular adaptation to low oxygen environments. ARNT is also a dimeric partner for the Ah receptor (AHR), and this comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfaa845b1b759360e95d933dda8744f4
https://doi.org/10.1074/jbc.m400784200
https://doi.org/10.1074/jbc.m400784200