Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Jacqueline A. Upcroft"'
Autor:
David Leitsch, Kenia G. Krauer, Kevin S. W. Tan, Jacqueline A. Upcroft, Anita Burgess, Lars Eckmann, Peter Upcroft, Linda A. Dunn, Michael Duchêne
Publikováno v:
Journal of Antimicrobial Chemotherapy. 66:1756-1765
Objectives: The mechanism of action of, and resistance to, metronidazole in the anaerobic (or micro-aerotolerant) protozoan parasite Giardia lamblia has long been associated with the reduction of ferredoxin (Fd) by the enzyme pyruvate:ferredoxin oxid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02e2301e45cac9a52e2d0fb36f39f8ca
https://doi.org/10.1093/jac/dkr192
https://doi.org/10.1093/jac/dkr192
Autor:
Richard I. Webb, Peter Upcroft, Janelle M. Wright, Peter J. O'Donoghue, Jacqueline A. Upcroft
Publikováno v:
Journal of Eukaryotic Microbiology. 57:171-176
Trichomonas vaginalis is the most common sexually transmitted protozoan in the world and its resistance to metronidazole is increasing. The purpose of this study was to demonstrate that clinical metronidazole resistance in T. vaginalis does not occur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b39039627b944cf56cdb97d9bdc89cd
https://doi.org/10.1111/j.1550-7408.2009.00455.x
https://doi.org/10.1111/j.1550-7408.2009.00455.x
Autor:
Petr Hruz, Yukiko Miyamoto, Diane Smith, Leo V. Arzu, Lars Eckmann, Valery V. Fokin, Carlos A. Valdez, K. Kangas, Peter Upcroft, Yolanda S. Andersen, Jacqueline A. Upcroft, K. Barry Sharpless, Sabrina E. Brown, Barbara J. Davids, Jonathan C. Tripp, Jaroslaw Kalisiak, Frances D. Gillin
Publikováno v:
Journal of Medicinal Chemistry. 52:4038-4053
Infections with the diarrheagenic pathogen, Giardia lamblia, are commonly treated with the 5-nitroimidazole (5-NI) metronidazole (Mz), and yet treatment failures and Mz resistance occur. Using a panel of new 2-ethenyl and 2-ethanyl 5-NI derivatives,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ba1bf53af65d7c81620620ee05325dd
https://doi.org/10.1021/jm900356n
https://doi.org/10.1021/jm900356n
Publikováno v:
Europe PubMed Central
The cytidine triphosphate synthetase genes from three diverse strains of Giardia duodenalis have been sequenced and found to vary significantly from one another. The isolates were chosen as representatives of three demes as determined by several crit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5af003c1fba2ead36f8da25924d09c7e
https://doi.org/10.1111/j.1550-7408.1997.tb05957.x
https://doi.org/10.1111/j.1550-7408.1997.tb05957.x
Autor:
Linda A. Dunn, Janelle M. Wright, Tina S. Skinner-Adams, Katherine T. Andrews, James S. McCarthy, Jacqueline A. Upcroft, Peter Upcroft
Publikováno v:
International Journal of Antimicrobial Agents. 29:98-102
Antiretroviral protease inhibitors were assessed in vitro for their activity against Giardia duodenalis and Trichomonas vaginalis. Kaletra (a co-formulation of ritonavir and lopinavir) was the most effective overall, with 50% effective drug concentra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::072b177261d4c466e2ee69913ede1425
https://doi.org/10.1016/j.ijantimicag.2006.08.026
https://doi.org/10.1016/j.ijantimicag.2006.08.026
Publikováno v:
Cell Research. 13:239-249
Trichomoniasis is the most common, sexually transmitted infection. It is caused by the flagellated protozoan parasite Trichomonas vaginalis. Symptoms include vaginitis and infections have been associated with preterm delivery, low birth weight and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d922f91a7c5b512a2f49e93703bc9f3
https://doi.org/10.1038/sj.cr.7290169
https://doi.org/10.1038/sj.cr.7290169
Autor:
David J. McMillan, Colleen Olive, Jacqueline A. Upcroft, David C. Jackson, Michael R. Batzloff, Linda A. Dunn, Peter Upcroft, Weiguang Zeng
Publikováno v:
Vaccine. 20:2635-2640
Primary vaccine strategies against group A streptococci (GAS) have focused on the M protein-the target of opsonic antibodies important for protective immunity. We have previously reported protection of mice against GAS infection following parenteral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fea13c207335f3eaf1b05fbf0b88933
https://doi.org/10.1016/s0264-410x(02)00206-2
https://doi.org/10.1016/s0264-410x(02)00206-2
Publikováno v:
European Journal of Protistology. 37:273-280
The intestinal, parasitic protozoa comprising the genus Giardia are major aetiological agents of diarrhoeal disease in numerous vertebrates, including humans, livestock and domestic pets. In previous investigations, morphological characteristics, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f863bcf25bc5f9e23461758fc4fd157
https://doi.org/10.1078/0932-4739-00818
https://doi.org/10.1078/0932-4739-00818
Publikováno v:
International Journal for Parasitology. 30:129-136
Numerous studies have demonstrated various strain differences between Giardia isolates, but little is known about the immunology and pathogenesis of infections. This study aimed to compare host responses to strains of Giardi duodenalis differing in l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd9eb227f707235960b92bac163a0d08
https://doi.org/10.1016/s0020-7519(99)00181-2
https://doi.org/10.1016/s0020-7519(99)00181-2
Autor:
Peter Upcroft, Jacqueline A. Upcroft
Publikováno v:
Protist. 150:17-23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f8be75fe3ef509b382721712db0725c
https://doi.org/10.1016/s1434-4610(99)70005-2
https://doi.org/10.1016/s1434-4610(99)70005-2