Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Jacqueline A. Sluijs"'
Autor:
Vanessa Donega, Astrid T. van der Geest, Jacqueline A. Sluijs, Roland E. van Dijk, Chi Chiu Wang, Onur Basak, R. Jeroen Pasterkamp, Elly M. Hol
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
The decline in neurogenesis following birth is accompanied with a quiescent state characteristic of neural progenitors of the adult brain. Here, the authors identify the Wnt pathway antagonist SFRP1 as a potential signal that promotes quiescence and
Externí odkaz:
https://doaj.org/article/265abcfd4aa8493cbccb075805ee75b0
Autor:
Rebeca Uceda-Castro, Jessy V. van Asperen, Claire Vennin, Jacqueline A. Sluijs, Emma J. van Bodegraven, Andreia S. Margarido, Pierre A. J. Robe, Jacco van Rheenen, Elly M. Hol
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Glioma is the most common form of malignant primary brain tumours in adults. Their highly invasive nature makes the disease incurable to date, emphasizing the importance of better understanding the mechanisms driving glioma invasion. Glial f
Externí odkaz:
https://doaj.org/article/b501743dc3ad44f6bf599962b165fe6f
Publikováno v:
Parkinson's Disease, Vol 2012 (2012)
Dementia is a common feature in Parkinson’s disease (PD) and is considered to be the result of limbic and cortical Lewy bodies and/or Alzheimer changes. Astrogliosis may also affect the development of dementia, since it correlates well with declini
Externí odkaz:
https://doaj.org/article/7976524959344e8989bfeff843df93c0
Autor:
Tamar Smit, Paul R. Ormel, Jacqueline A. Sluijs, Lianne A. Hulshof, Jinte Middeldorp, Lot D. de Witte, Elly M. Hol, Vanessa Donega
Publikováno v:
Brain, Behavior, and Immunity. 100:219-230
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a33af40c50c400a1e7f4be1a1647a452
https://doi.org/10.1016/j.bbi.2021.12.001
https://doi.org/10.1016/j.bbi.2021.12.001
Autor:
Richard L.M. Faull, Jacqueline A. Sluijs, Lasse Brandt, Josef Priller, Francisco Fernández-Klett, Maurice A. Curtis, Jinte Middeldorp, Elly M. Hol, Laura W. Harris, Sabine Bahn, Basim Abuelnor, Camila Fernández-Zapata
Publikováno v:
Brain Pathology
Brain pathology 30(6), 1071-1086 (2020). doi:10.1111/bpa.12897
Brain pathology 30(6), 1071-1086 (2020). doi:10.1111/bpa.12897
Pericytes are vascular mural cells that surround capillaries of the central nervous system (CNS). They are crucial for brain development and contribute to CNS homeostasis by regulating blood–brain barrier function and cerebral blood flow. It has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c83072a81b007cc9892038c7fb723e51
https://doi.org/10.1111/bpa.12897
https://doi.org/10.1111/bpa.12897
Autor:
Vanessa Donega, Jacqueline A. Sluijs, Paul R. Ormel, T. Smit, L D de Witte, Elly M. Hol, Jinte Middeldorp, Lianne A. Hulshof
Dysregulation of microglial function contributes to Alzheimer’s disease (AD) pathogenesis. Several genetic and transcriptome studies have revealed microglia specific genetic risk factors, and changes in microglia expression profiles in AD pathogene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2028214f6c6076cc9f807dd46aec2e72
https://doi.org/10.1101/2021.08.12.456055
https://doi.org/10.1101/2021.08.12.456055
Autor:
Tamar, Smit, Paul R, Ormel, Jacqueline A, Sluijs, Lianne A, Hulshof, Jinte, Middeldorp, Lot D, de Witte, Elly M, Hol, Vanessa, Donega
Publikováno v:
Brain, behavior, and immunity. 100
Dysregulation of microglial function contributes to Alzheimer's disease (AD) pathogenesis. Several genetic and transcriptome studies have revealed microglia specific genetic risk factors, and changes in microglia expression profiles in AD pathogenesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0da8ccd5e0f94dadfe6e3becd3e930d9
https://pubmed.ncbi.nlm.nih.gov/34896594
https://pubmed.ncbi.nlm.nih.gov/34896594
Autor:
Jessy V. van Asperen, Miriam E. van Strien, Emma J. van Bodegraven, Coen B J van Deursen, Oscar M. J. A. Stassen, Pierre A. Robe, Elly M. Hol, Jacqueline A. Sluijs
Publikováno v:
The FASEB Journal, 33(11), 12941-12959. FASEB
Gliomas are the most common primary brain tumors. Their highly invasive character and the heterogeneity of active oncogenic pathways within single tumors complicate the development of curative therapies and cause poor patient prognosis. Glioma cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22f98a81dfc825cd528e08052a5e406f
https://research.tue.nl/en/publications/4b991fe4-0534-4fa6-95b6-61354ccf9ca8
https://research.tue.nl/en/publications/4b991fe4-0534-4fa6-95b6-61354ccf9ca8
Publikováno v:
The FASEB Journal. 35
The glial fibrillary acidic protein (GFAP) is a type III intermediate filament (IF) protein that is highly expressed in astrocytes, neural stem cells, and in gliomas. Gliomas are a heterogeneous group of primary brain tumors that arise from glia cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92c5b580568b76d8c6a162ecff8c3cf8
https://doi.org/10.1096/fj.202001767r
https://doi.org/10.1096/fj.202001767r
Autor:
Vanessa, Donega, Astrid T, van der Geest, Jacqueline A, Sluijs, Roland E, van Dijk, Chi Chiu, Wang, Onur, Basak, R Jeroen, Pasterkamp, Elly M, Hol
Publikováno v:
Nature communications. 13(1)
Following the decline of neurogenesis at birth, progenitors of the subventricular zone (SVZ) remain mostly in a quiescent state in the adult human brain. The mechanisms that regulate this quiescent state are still unclear. Here, we isolate CD271
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d2e5183859f78daa4f182f290e7fbec9
https://pubmed.ncbi.nlm.nih.gov/35210419
https://pubmed.ncbi.nlm.nih.gov/35210419