Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jacqueline A. O'Shaughnessy"'
Autor:
Anthony J. DeStefano, Daniel Tang, Jacqueline A. O'Shaughnessy, Marian Kelley, Ajai K. Chaudhary, S. Peter King, Russell Weiner, Douglas M. Fast, C. T. Viswanathan
Publikováno v:
The AAPS Journal. 11:238-241
The Conference Report of the 3rd AAPS/FDA Bioanalytical Workshop (Crystal City III) endorsed the concept that assay methods supporting bioanalytical data in submissions must demonstrate assay reproducibility by using incurred samples. The present Wor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8701cdb5f80696bcc8caa8e767717bdd
https://doi.org/10.1208/s12248-009-9100-9
https://doi.org/10.1208/s12248-009-9100-9
Publikováno v:
Biochemical Pharmacology. 50:1925-1932
Phosphorothioate insecticides such as parathion (O,O-diethyl-O-p-nitrophenyl phosphorothioate) undergo P450-dependent oxidative desulfuration, leading to both activation and detoxification of these compounds. Consequently, alterations in P450-depende
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::855f4b3346e1af70047d1cae5305bed7
https://doi.org/10.1016/0006-2952(95)02089-6
https://doi.org/10.1016/0006-2952(95)02089-6
Publikováno v:
Ligand-Binding Assays: Development, Validation, and Implementation in the Drug Development Arena
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd5a0616b9270686243f78af04313b50
https://doi.org/10.1002/9780470541517.ch12
https://doi.org/10.1002/9780470541517.ch12
Publikováno v:
Pharmacologytoxicology. 77(1)
The effects of induction of various forms of cytochromes P450 by chemicals like phenobarbital on the hepatic oxidative desulfuration and acute toxicity of the phosphorothioate insecticide parathion have been well-characterized. However, the effects o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0af47451297e4fc235d29ef97ab6a7d
https://pubmed.ncbi.nlm.nih.gov/8532607
https://pubmed.ncbi.nlm.nih.gov/8532607