Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Jacqueline A. James"'
Autor:
Michelle K. Greene, Peter Smyth, Andrew English, Joseph McLaughlin, Magda Bucholc, Janice Bailie, Julie McCarroll, Margaret McDonnell, Alison Watt, George Barnes, Mark Lynch, Kevan Duffin, Gerard Duffy, Claire Lewis, Jacqueline A. James, Alan W. Stitt, Tom Ford, Maurice O'Kane, Taranjit Singh Rai, Anthony J. Bjourson, Christopher Cardwell, J Stuart Elborn, David S. Gibson, Christopher J. Scott
Publikováno v:
Heliyon, Vol 10, Iss 2, Pp e24184- (2024)
Background: With the spread of SARS-CoV-2 impacting upon public health directly and socioeconomically, further information was required to inform policy decisions designed to limit virus spread during the pandemic. This study sought to contribute to
Externí odkaz:
https://doaj.org/article/7d4d4ec7cbc4481399abfb0592ef4565
Autor:
Niamh McKerr, Adone Mohd-Sarip, Hannah Dorrian, Conor Breen, Jacqueline A. James, Stephen McQuaid, Ian G. Mills, Karen D. McCloskey
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Prostate cancer is often treated by perturbing androgen receptor signalling. CACNA1D, encoding CaV1.3 ion channels is upregulated in prostate cancer. Here we show how hormone therapy affects CACNA1D expression and CaV1.3 function. Human pros
Externí odkaz:
https://doaj.org/article/8aae43c94ec84d0282f547ff3e22e3c2
Autor:
Stephanie G. Craig, Svenja Mende, Matthew P. Humphries, Victoria Bingham, Amélie Viratham Pulsawatdi, Maurice B. Loughrey, Helen G. Coleman, Stephen McQuaid, Richard H. Wilson, Sandra Van Schaeybroeck, Jacqueline A. James, Manuel Salto‐Tellez
Publikováno v:
Molecular Oncology, Vol 15, Iss 12, Pp 3317-3328 (2021)
Clinical trials for MET inhibitors have demonstrated limited success for their use in colon cancer (CC). However, clinical efficacy may be obscured by a lack of standardisation in MET assessment for patient stratification. In this study, we aimed to
Externí odkaz:
https://doaj.org/article/0b8be54a07784f57bd958f3c8b5f5b03
Autor:
Emily McIlvanna, Gerard J. Linden, Stephanie G. Craig, Fionnuala T. Lundy, Jacqueline A. James
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract There is a growing level of interest in the potential role inflammation has on the initiation and progression of malignancy. Notable examples include Helicobacter pylori-mediated inflammation in gastric cancer and more recently Fusobacterium
Externí odkaz:
https://doaj.org/article/4fe7821000194282b227188231027b4b
Autor:
Kris D. McCombe, Stephanie G. Craig, Amélie Viratham Pulsawatdi, Javier I. Quezada-Marín, Matthew Hagan, Simon Rajendran, Matthew P. Humphries, Victoria Bingham, Manuel Salto-Tellez, Richard Gault, Jacqueline A. James
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 4840-4853 (2021)
The growth of digital pathology over the past decade has opened new research pathways and insights in cancer prediction and prognosis. In particular, there has been a surge in deep learning and computer vision techniques to analyse digital images. Co
Externí odkaz:
https://doaj.org/article/f0c15eb6333743c6b9d1efb413a0bc73
Autor:
Amélie Viratham Pulsawatdi, Stephanie G. Craig, Victoria Bingham, Kris McCombe, Matthew P. Humphries, Seedevi Senevirathne, Susan D. Richman, Phil Quirke, Leticia Campo, Enric Domingo, Timothy S. Maughan, Jacqueline A. James, Manuel Salto‐Tellez
Publikováno v:
Molecular Oncology, Vol 14, Iss 10, Pp 2384-2402 (2020)
Multiplex immunofluorescence is a powerful tool for the simultaneous detection of tissue‐based biomarkers, revolutionising traditional immunohistochemistry. The Opal methodology allows up to eight biomarkers to be measured concomitantly without cro
Externí odkaz:
https://doaj.org/article/ddaedcd62c55444cbbab846a80836163
Autor:
Maria Walls, Gerard M. Walls, Jacqueline A. James, Kyle T. Crawford, Hossam Abdulkhalek, Tom B. Lynch, Aaron J. Peace, Terry E. McManus, O. Rhun Evans
Publikováno v:
BMC Pulmonary Medicine, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background ALK-rearrangement is observed in
Externí odkaz:
https://doaj.org/article/8eb61151eb164e278ed547c8ac169ab2
Autor:
Samuel F. Bakhoum, Benjamin Izar, Eileen E. Parkes, Alexander N. Shoushtari, Charles Swanton, Olivier Elemento, Jedd D. Wolchok, Simon N. Powell, Neil Vasan, Anusha Kalbasi, Shin-San Michael Su, Nadeem Riaz, Jorge S. Reis-Filho, Hannah Y. Wen, Taha Merghoub, Travis J. Hollmann, Benjamin J. DiPardo, Lee Gottesdiener, Chantal Pauli, Peng Li, Julie-Ann Cavallo, Princesca Dorsaint, Maria Laura Martin, Hao Wei Li, Rohan Bareja, Dhruva Biswas, Ieva Usaite, Kevin Litchfield, Sreeram Vallabhaneni, Johannes C. Melms, Matthew G. Hanna, Jacqueline A. James, Manuel Salto-Tellez, Matthew P. Humphries, Roshan K. Sriram, John Kwon, Sarah E. Bettigole, Walid K. Chatila, Ninjit Dhanota, Mercedes A. Duran, Jun Li
Supplementary Figures and Methods in PDF format
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::635ea996437975f580871317155e428c
https://doi.org/10.1158/2159-8290.22540268.v1
https://doi.org/10.1158/2159-8290.22540268.v1
Autor:
Samuel F. Bakhoum, Benjamin Izar, Eileen E. Parkes, Alexander N. Shoushtari, Charles Swanton, Olivier Elemento, Jedd D. Wolchok, Simon N. Powell, Neil Vasan, Anusha Kalbasi, Shin-San Michael Su, Nadeem Riaz, Jorge S. Reis-Filho, Hannah Y. Wen, Taha Merghoub, Travis J. Hollmann, Benjamin J. DiPardo, Lee Gottesdiener, Chantal Pauli, Peng Li, Julie-Ann Cavallo, Princesca Dorsaint, Maria Laura Martin, Hao Wei Li, Rohan Bareja, Dhruva Biswas, Ieva Usaite, Kevin Litchfield, Sreeram Vallabhaneni, Johannes C. Melms, Matthew G. Hanna, Jacqueline A. James, Manuel Salto-Tellez, Matthew P. Humphries, Roshan K. Sriram, John Kwon, Sarah E. Bettigole, Walid K. Chatila, Ninjit Dhanota, Mercedes A. Duran, Jun Li
Cytosolic DNA is characteristic of chromosomally unstable metastatic cancer cells, resulting in constitutive activation of the cGAS–STING innate immune pathway. How tumors co-opt inflammatory signaling while evading immune surveillance remains unkn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af51a233154e60a4e2bb2d77e8270d96
https://doi.org/10.1158/2159-8290.c.6549335
https://doi.org/10.1158/2159-8290.c.6549335
Autor:
Dennis J. McCance, Simon S. McDade, Jacqueline A. James, Shauna M. Lambe, Gerard P. Quinn, Stephanie G. Craig, Adam Pickard, Kirtiman Srivastava
Figure S5 shows (A) venn diagram comparing E6/E7-HFK TP63 ChIP-seq peaks with published normal HFK TP63 ChIP-seq (McDade et al, 2014) (B) Visualisation of E6/E7 and normal HFK TP63 ChIP-seq tracks around CDH1 loci annotated with Encode histone modifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff3826c7032c6d824af0d87b2aa10c9
https://doi.org/10.1158/1078-0432.22476041
https://doi.org/10.1158/1078-0432.22476041