Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Jacqueline A Quandt"'
Autor:
Carles Vilariño-Güell, Alexander Zimprich, Filippo Martinelli-Boneschi, Bruno Herculano, Zhe Wang, Fuencisla Matesanz, Elena Urcelay, Koen Vandenbroeck, Laura Leyva, Denis Gris, Charbel Massaad, Jacqueline A Quandt, Anthony L Traboulsee, Mary Encarnacion, Cecily Q Bernales, Jordan Follett, Irene M Yee, Maria G Criscuoli, Angela Deutschländer, Eva M Reinthaler, Tobias Zrzavy, Elisabetta Mascia, Andrea Zauli, Federica Esposito, Antonio Alcina, Guillermo Izquierdo, Laura Espino-Paisán, Jorge Mena, Alfredo Antigüedad, Patricia Urbaneja-Romero, Jesús Ortega-Pinazo, Weihong Song, A Dessa Sadovnick
Publikováno v:
PLoS Genetics, Vol 15, Iss 6, p e1008180 (2019)
Multiple sclerosis (MS) is an inflammatory disease of the central nervous system characterized by myelin loss and neuronal dysfunction. Although the majority of patients do not present familial aggregation, Mendelian forms have been described. We per
Externí odkaz:
https://doaj.org/article/3aec66c42d53419dadaeb628391f9fea
Autor:
Xinhui Li, Kory R Johnson, Mark Bryant, Abdel G Elkahloun, Marcelo Amar, Alan T Remaley, Ranil De Silva, John M Hallenbeck, Jacqueline A Quandt
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20620 (2011)
Mucosal tolerance to E-selectin prevents stroke and protects against ischemic brain damage in experimental models of stroke studying healthy animals or spontaneously hypertensive stroke-prone rats. A reduction in inflammation and neural damage was as
Externí odkaz:
https://doaj.org/article/a44d1163a2284bcaaee014025419ec65
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundMultiple sclerosis (MS) is divided into three clinical phenotypes: relapsing–remitting MS (RRMS), secondary progressive MS (SPMS), and primary progressive MS (PPMS). It is unknown to what extent SPMS and PPMS pathophysiology share inflamm
Externí odkaz:
https://doaj.org/article/773a1ef78dab466bb65a4bb84721281b
Autor:
Ruth Ann Marrie, Mark Allegretta, Lisa F. Barcellos, Bruce Bebo, Peter A. Calabresi, Jorge Correale, Benjamin Davis, Philip L. De Jager, Christiane Gasperi, Carla Greenbaum, Anne Helme, Bernhard Hemmer, Pamela Kanellis, Walter Kostich, Douglas Landsman, Christine Lebrun-Frenay, Naila Makhani, Kassandra L. Munger, Darin T. Okuda, Daniel Ontaneda, Ronald B. Postuma, Jacqueline A. Quandt, Sharon Roman, Shiv Saidha, Maria Pia Sormani, Jon Strum, Pamela Valentine, Clare Walton, Kathleen M. Zackowski, Yinshan Zhao, Helen Tremlett
Publikováno v:
Nature Reviews Neurology. 18:559-572
A prodrome is an early set of signs or symptoms that indicate the onset of a disease before more typical symptoms develop. Prodromal stages are well recognized in some neurological and immune-mediated diseases such as Parkinson disease, schizophrenia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d635bd73e5ce7f6a41164de6afbae3e0
https://doi.org/10.1038/s41582-022-00686-x
https://doi.org/10.1038/s41582-022-00686-x
Autor:
Abhinav Ajaykumar, Loïc C. Caloren, Tetiana Povshedna, Anthony Y.Y. Hsieh, Aya Zakaria, Renying Cai, Marie-Soleil R. Smith, Connor A.H. Thompson, Pierre Becquart, Prakruti Uday, Rutuja Pattanshetti, Jacqueline A. Quandt, Judy M.Y. Wong, Hélène C.F. Côté
Publikováno v:
AIDS (London, England). 37(1)
Given the success of combination antiretroviral therapy (cART) in treating HIV viremia, drug toxicity remains an area of interest in HIV research. Despite newer integrase strand transfer inhibitors (InSTIs), such as dolutegravir (DTG) and raltegravir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7586f1cc6ece44df72ebf4ee671b7bcb
https://pubmed.ncbi.nlm.nih.gov/36399361
https://pubmed.ncbi.nlm.nih.gov/36399361
Autor:
Cornelia Laule, Jacqueline A. Quandt, Emily Kamma, Anthony Traboulsee, Pierre Becquart, Carles Vilariño-Güell, Irene M. Vavasour, Alice Schabas
Publikováno v:
Multiple sclerosis and related disorders. 56
CD5 antigen-like (CD5L) protein is a macrophage-secreted protein with roles in immunomodulation and lipid homeostasis. We compared serum CD5L levels in healthy controls to individuals diagnosed with clinically isolated syndrome, relapsing remitting (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf0ee119de658434b99824be33ed596c
https://pubmed.ncbi.nlm.nih.gov/34638097
https://pubmed.ncbi.nlm.nih.gov/34638097
Publikováno v:
Brain Pathology (Zurich, Switzerland)
The CD1 protein family present lipid antigens to the immune system. CD1d has been observed in the CNS of MS patients, yet no studies have quantitatively characterized this expression and related it to inflammatory demyelinative activity in MS plaques
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::565ba6985f83ec8ad5cb71794ef4bc44
http://europepmc.org/articles/PMC6916356
http://europepmc.org/articles/PMC6916356
Autor:
Jacqueline A. Quandt, Emily Kamma, Carles Vilariño-Güell, Mary Encarnacion, Cecily Q. Bernales, Pierre Becquart
BackgroundThe development of effective treatments for multiple sclerosis (MS), and in particular its progressive forms, is hampered by the lack of etiologically relevant cellular and animal models of human disease. Models that recapitulate the biolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9767d5bd6a5dbdaa2c02891292cc792a
https://doi.org/10.1101/2021.03.17.435678
https://doi.org/10.1101/2021.03.17.435678
Autor:
Jacqueline A. Quandt, Cecily Q. Bernales, Carles Vilariño-Güell, A. Dessa Sadovnick, Mary Encarnacion, Anthony Traboulsee, Lisa F Popplewell
Publikováno v:
Immunogenetics. 72(6-7)
Genetic and functional analyses of the inflammasome suggest a role for this multiprotein complex in the biological mechanisms leading to the onset and progression of multiple sclerosis (MS). Nucleotide-binding, leucine-rich repeat (NLR) receptors tri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ba230c66db06395334d1622fdf271ea
https://pubmed.ncbi.nlm.nih.gov/32529290
https://pubmed.ncbi.nlm.nih.gov/32529290
Autor:
Cornelia Laule, Irene M. Vavasour, Jasmine Gill, Virginia Devonshire, David K.B. Li, Sophie Stukas, Robert Carruthers, G. R. Wayne Moore, Shannon H. Kolind, Anthony Traboulsee, Pierre Becquart, Jacqueline A. Quandt, Jackie T Yik, Ana-Luiza Sayao, John Petkau, Alice Schabas, Cheryl L. Wellington, Roger Tam
Publikováno v:
Multiple Sclerosis and Related Disorders. 57:103366
Background Neurofilaments are cytoskeletal proteins that are detectable in the blood after neuroaxonal injury. Multiple sclerosis (MS) disease progression, greater lesion volume, and brain atrophy are associated with higher levels of serum neurofilam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00dfa391959e7062f03e8aee2d7239cf
https://doi.org/10.1016/j.msard.2021.103366
https://doi.org/10.1016/j.msard.2021.103366