Výsledky vyhledávání - "Jacque Mitchen"

Repeated Low-Dose Mucosal Simian Immunodeficiency Virus SIVmac239 Challenge Results in the Same Viral and Immunological Kinetics as High-Dose Challenge: a Model for the Evaluation of Vaccine Efficacy in Nonhuman Primates

Autor: Jason J. Stephany, Adrian B. McDermott, Ivna P. de Souza, Jessica Furlott, Jacque Mitchen, David I. Watkins, Levi Yant, Shari M. Piaskowski

Publikováno v: Journal of Virology. 78:3140-3144

Simian immunodeficiency virus (SIV) challenge of rhesus macaques provides a relevant model for the assessment of human immunodeficiency virus (HIV) vaccine strategies. To ensure that all macaques become infected, the vaccinees and controls are expose

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83a1f1cbddabc2e2e4028936b17f34b0
https://doi.org/10.1128/jvi.78.6.3140-3144.2004

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Importance of the CD3 marker for evaluating changes in rhesus macaque CD4/CD8 T-cell ratios

Autor: Alex V. MacDougall, C. David Pauza, Eva G. Rakasz, Jody Helgeland, Maria T. Zayas, Jacque Mitchen, Marta Dykhuizen, Jennifer Ceman

Publikováno v: Cytometry. 40:69-75

Background Until recently, there were no CD3 antibodies that crossreacted with rhesus macaque T cells. Consequently, studies relying on CD8 counts or CD4/CD8 ratios enumerated this subpopulation on the basis of CD8+ or CD8bright+ staining. We used a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b67aa125e36b7af14594544b3e2a5342
https://doi.org/10.1002/(sici)1097-0320(20000501)40:1<69::aid-cyto9>3.0.co

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Lymphocyte Activation during Acute Simian/Human Immunodeficiency Virus SHIV 89.6PD Infection in Macaques

Autor: Charles C. Brown, Marta Dykhuizen, Moiz Kitabwalla, Marianne Wallace, Jacque Mitchen, Douglas Horejsh, Mahmoud Djavani, Paul M. Waterman, Parul Trivedi, C. David Pauza

Publikováno v: Journal of Virology. 73:10236-10244

Host-virus interactions control disease progression in human immunodeficiency virus-infected human beings and in nonhuman primates infected with simian or simian/human immunodeficiency viruses (SHIV). These interactions evolve rapidly during acute in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6983034d87fb3998355d01794fd33619
https://doi.org/10.1128/jvi.73.12.10236-10244.1999

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Rapid and slow progressors differ by a single MHC class I haplotype in a family of MHC-defined rhesus macaques infected with SIV

Autor: C. David Pauza, David I. Watkins, Leslie A. Knapp, Jacque Mitchen, David T. Evans, Marta Dykhuizen, David C. Montefiori, Peicheng Jing

Publikováno v: Immunology Letters. 66:53-59

Highly polymorphic HLA class I molecules may influence rates of disease progression of HIV-infected individuals. Recent evidence suggests that individuals who mount vigorous CTL responses to multiple HIV-1 epitopes have reduced viral loads, and survi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee797fcdc9ccc8c94489ba87a9a1b05f
https://doi.org/10.1016/s0165-2478(98)00151-5

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CD4 + -T-Cell and CD20 + -B-Cell Changes Predict Rapid Disease Progression after Simian-Human Immunodeficiency Virus Infection in Macaques

Autor: Krista K. Steger, Jacque Mitchen, Marianne Wallace, David C. Montefiori, B L Preuninger, Yichen Lu, C. D. Pauza, J Thomson, Hinds Pw, Marta Dykhuizen

Publikováno v: Journal of Virology. 72:1600-1605

Simian-human immunodeficiency virus 89.6PD (SHIV 89.6PD ) was pathogenic after intrarectal inoculation of rhesus macaques. Infection was achieved with a minimum of 2,500 tissue culture infectious doses of cell-free virus stock, and there was no evide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84642650966fc265f6ffd63c6a38a470
https://doi.org/10.1128/jvi.72.2.1600-1605.1998

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Use of a DNA microfluorometric assay to measure proliferative response of mink lung cells to purified TGFβ and to TGFβ activity found in prostate cell conditioned medium

Autor: Deborah Bletzinger, Randall P. Rago, George Wilding, Jacque Mitchen

Publikováno v: In Vitro Cellular & Developmental Biology - Animal. 31:692-697

The proliferative response of Mv1Lu cells to purified TGF beta 1, or TGF beta-like activity released by various cells into medium conditioned over a 24-h period was quantitated by adapting a rapid DNA fluorometric assay. Acid activation of the condit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::486aadb5ed44f0c60250f74dae9caa90
https://doi.org/10.1007/bf02634090

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Hemorrhagic fever occurs after intravenous, but not after intragastric, inoculation of rhesus macaques with lymphocytic choriomeningitis virus

Autor: Juan D Rodas, Peter B. Jahrling, Jacque Mitchen, Maria S. Salvato, Carol Emerson, Mahmoud Djavani, Juan C. Zapata, Amy L. Usborne, Igor S. Lukashevich

Publikováno v: Journal of medical virology. 67(2)

Arenaviruses can cause hemorrhagic fever and death in primates and guinea pigs, but these viruses are not highly pathogenic for most rodent carriers. In the United States, arenaviruses precipitated outbreaks of hepatitis in captive monkeys, and they

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c8081811f7a7a24d731d8f15ce15f5a
https://pubmed.ncbi.nlm.nih.gov/11992578

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Gammadelta T cell receptor repertoire in blood and colonic mucosa of rhesus macaques

Autor: Glen S. Hatfield, Peter Evans, Maria T. Zayas, Marta Dykhuizen, Eva G. Rakasz, Jacque Mitchen, Tracy J. Ruckward, C. David Pauza, Alex V. MacDougall, Jody L. Helgelund

Publikováno v: Journal of medical primatology. 29(6)

Although their precise roles are not well defined, gammadelta T lymphocytes are recognized as regular components of immune responses. These cells express a limited T cell receptor repertoire and they can be stimulated by soluble ligands without conve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e840781f85e1db792ce5d6a20053b33
https://pubmed.ncbi.nlm.nih.gov/11168829

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Whole body positron emission tomography imaging of activated lymphoid tissues during acute simian-human immunodeficiency virus 89.6PD infection in rhesus macaques

Autor: C. David Pauza, Scott B. Perlman, Jacque Mitchen, Joan M. Hanson, Robert W. Pyzalski, Charles C. Brown, Marianne Wallace, Yichen Lu, Douglas Horejsh, Mahmoud Djavani

Publikováno v: Virology. 274(2)

Mechanisms of acute retroviral pathogenesis have been examined during primary infection of rhesus macaques with simian–human immunodeficiency virus 89.6PD (SHIV89.6PD). During acute infection, between initial exposure and establishment of antigen-s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c38516cd457dd9db4f58236708dfcba
https://pubmed.ncbi.nlm.nih.gov/10964769

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Extended culturing of androgen-responsive human primary epithelial prostate cell isolates by continuous treatment with interstitial collagenase

Autor: Terry D. Oberley, Jacque Mitchen, George Wilding

Publikováno v: The Prostate. 30(1)

Continuous culturing of two distinct human prostate specimens in the presence of interstitial collagenase added directly to conventional medium resulted in the isolation and extended growth of primary epithelial prostate cell (PEPC) cultures from eac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebd8d3a4b47e66d8feb9df37808511ca
https://pubmed.ncbi.nlm.nih.gov/9018330

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