Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Jacqeuline M. O'Connor"'
Autor:
Baole Wang, Mary K. Joseph, Haichao Zhang, Alex R. Shoemaker, Steven W. Elmore, Paul Nimmer, David Frost, Michael J. Mitten, Anatol Oleksijew, Stephen W. Fesik, Yu Xiao, Jacqeuline M. O’Connor, Christin Tse, Scott L. Ackler, Saul H. Rosenberg
Publikováno v:
Blood. 108:825-825
ABT-263 is an orally bioavailable small molecule inhibitor of Bcl-2 family proteins with a Ki of ≤ 1 nM against Bcl-2, Bcl-XL, and Bcl-w. Non-Hodgkin’s B-cell lymphomas represent clinically relevant disease targets for this molecule due, in part,