Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Jacobus Slabbert"'
Autor:
Charnay Cunningham, Maryna de Kock, Monique Engelbrecht, Xanthene Miles, Jacobus Slabbert, Charlot Vandevoorde
Publikováno v:
Frontiers in Public Health, Vol 9 (2021)
The number of proton therapy facilities and the clinical usage of high energy proton beams for cancer treatment has substantially increased over the last decade. This is mainly due to the superior dose distribution of proton beams resulting in a redu
Externí odkaz:
https://doaj.org/article/6556ac85987e4698b029ed2de419533f
Estimating the Relative Biological Effectiveness of Auger Electron Emitter 123I in Human Lymphocytes
Autor:
Hein Fourie, Shankari Nair, Xanthene Miles, Daniel Rossouw, Philip Beukes, Richard T. Newman, Jan Rijn Zeevaart, Charlot Vandevoorde, Jacobus Slabbert
Publikováno v:
Frontiers in Physics, Vol 8 (2020)
Auger electron emitters are considered to be a promising strategy for targeted radionuclide therapy of metastatic diseases, given their high linear energy transfer (LET) and short range in tissue which could potentially limit normal tissue toxicity.
Externí odkaz:
https://doaj.org/article/375f13f1512b4b59af7030300521cbfb
Autor:
Greet Wieme, Anne Vral, Kathleen Claes, Ans Baeyens, Ilse Coene, Bénédicte Brichard, Hélène Poirel, Rosalind Wainwright, Stephanie Vermeulen, Kim De Leeneer, Flavia Zita Francies, Janet Poole, Jacobus Slabbert
Publikováno v:
DNA Repair. 61:17-24
Fanconi Anaemia (FA) is an autosomal recessive disorder characterised by defects in DNA repair, associated with chromosomal instability and cellular hypersensitivity to DNA cross-linking agents such as mitomycin C (MMC). The FA repair pathway involve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c52f34ff9dad47dceb778720e757f1
https://doi.org/10.1016/j.dnarep.2017.11.001
https://doi.org/10.1016/j.dnarep.2017.11.001
Autor:
Kathleen Claes, Marshall Murdoch, Olivia Herd, A. Cairns, Anne Vral, Jacobus Slabbert, Flavia Zita Francies, Sarah Nietz, Ans Baeyens
Publikováno v:
International journal of radiation biology. 95(11)
Purpose: Based on clinical and molecular data, breast cancer is a heterogeneous disease. Breast cancers that have no expression of estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2) are defined as t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49aad1f2d27243579821f4260f697e07
https://pubmed.ncbi.nlm.nih.gov/31348739
https://pubmed.ncbi.nlm.nih.gov/31348739
Publikováno v:
The Breast Journal. 21:447-449
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7494d19ee4b57079133a53ea1b07e8e
https://doi.org/10.1111/tbj.12434
https://doi.org/10.1111/tbj.12434
Autor:
Julie Depuydt, Anne Vral, Bram Van Bockstaele, Jacobus Slabbert, Philip Beukes, Veerle Vandersickel
Publikováno v:
International Journal of Radiation Biology. 90:149-158
Purpose: To investigate both the formation of micronuclei (MN) and the induction and subsequent loss of phosphorylated histone H2AX foci (γH2AX foci) after in vitro exposure of human lymphocytes to either 60Co γ-rays or p(66)+ Be(40) neutrons.Mater
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76d16d7405af49e2efcd2cef5df620ab
https://doi.org/10.3109/09553002.2014.860252
https://doi.org/10.3109/09553002.2014.860252
Publikováno v:
Inorganic Chemistry Communications. 33:154-157
Preliminary experiments were conducted using the radiometal 67 Ga and a select series of thiosemicarbazones. A series of five monothiosemicarbazone ligands was synthesized via a Schiff-base condensation reaction. Radiolabelling studies were performed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbccf4f7eebbd1b28f5514df2a427f01
https://doi.org/10.1016/j.inoche.2013.04.025
https://doi.org/10.1016/j.inoche.2013.04.025
Autor:
Zwide Nxumalo, Jacobus Slabbert, Xanthene Muller, Ans Baeyens, Flavia Zita Francies, Trudy Smith, Anne Vral, Olivia Herd, Jeffrey Kotzen
Publikováno v:
MOLECULAR MEDICINE REPORTS
Molecular Medicine Reports
Molecular Medicine Reports
Cervical cancer is the second most common cancer amongst South African women and is the leading cause of cancer-associated mortality in this region. Several international studies on radiation-induced DNA damage in lymphocytes of cervical cancer patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fa0014378c372f5bada5fabc753ccab
https://biblio.ugent.be/publication/7166217/file/7166239
https://biblio.ugent.be/publication/7166217/file/7166239
Autor:
Tasha Wainstein, Ans Baeyens, Ilse Coene, Flavia Zita Francies, Anne Vral, Brecht Crombez, Bruce Poppe, A. Cairns, Jacobus Slabbert, K De Leeneer, T. Van Maerken, Kathleen Claes, Amanda Krause, Sarah Nietz, Robyn Kerr, H. Cubasch, Marshall Murdoch
Publikováno v:
BMC Cancer
Background Current knowledge of the aetiology of hereditary breast cancer in the four main South African population groups (black, coloured, Indian and white) is limited. Risk assessments in the black, coloured and Indian population groups are challe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ddab0007faf3d18bc75d7b6f845077a
https://doi.org/10.1186/s12885-015-1913-6
https://doi.org/10.1186/s12885-015-1913-6
Autor:
Ans Baeyens, Mike Morford, Marshall Murdoch, Jacobus Slabbert, Olivia Herd, A. Cairns, Dineshree Padiachy, Gary Katzman, Anne Vral, Flavia Zita Francies
Publikováno v:
Mutagenesis. 31(2)
The micronucleus assay (MN assay) is a well-established assay in genetic toxicology, biomonitoring of mutagen-exposed populations and chromosomal radiosensitivity testing. To evaluate the effect of storage time on the chromosomal radiosensitivity ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7f24a92c581a0a6f2441dd5d7488e74
https://pubmed.ncbi.nlm.nih.gov/26429940
https://pubmed.ncbi.nlm.nih.gov/26429940