Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jacobus P. Ungerer"'
Autor:
Huika Li, Thy Pham, Brett C. McWhinney, Jacobus P. Ungerer, Carel J. Pretorius, Derek J. Richard, Robin H. Mortimer, Michael C. d’Emden, Kerry Richard
Publikováno v:
International Journal of Endocrinology, Vol 2016 (2016)
Sex Hormone Binding Globulin (SHBG) is the major serum carrier of sex hormones. However, growing evidence suggests that SHBG is internalised and plays a role in regulating intracellular hormone action. This study was to determine whether SHBG plays a
Externí odkaz:
https://doaj.org/article/c8bf8e00bb8a4be9ab992d0d6eb6db6f
Autor:
Xiangju Wang, Chang Seong Kim, Benjamin C. Adams, Ray Wilkinson, Michelle M. Hill, Alok K. Shah, Ahmed Mohamed, Mriga Dutt, Monica S.Y. Ng, Jacobus P.J. Ungerer, Helen G. Healy, Andrew J. Kassianos
Publikováno v:
Redox Biology, Vol 70, Iss , Pp 103042- (2024)
Hypoxia is the key pathobiological trigger of tubular oxidative stress and cell death that drives the transition of acute kidney injury (AKI) to chronic kidney disease (CKD). The mitochondrial-rich proximal tubular epithelial cells (PTEC) are uniquel
Externí odkaz:
https://doaj.org/article/898c2efbe8a34d2eb160c44c13860921
Autor:
Tim Chang, Vesa Cheng, Matthew Rawlins, Prithviraj Thyagarajan, John Dyer, Brett C. McWhinney, Jacobus P.J. Ungerer, Jason A. Roberts
Publikováno v:
European Medical Journal Nephrology, Vol 8, Iss 1, Pp 54-58 (2020)
Prolonged intermittent renal replacement therapy (PIRRT) is emerging as an alternative to continuous renal replacement therapy as renal support for the critically ill. Unfortunately, dosing data are lacking for many antibiotics, including ceftriaxone
Externí odkaz:
https://doaj.org/article/10c724a48d834804a72dffd2fcf07f02
Autor:
Jessica H. Xu, Vesa Cheng, Matthew Rawlins, Joanne Lennon, David Morgan, Brett C. McWhinney, Jacobus P.J. Ungerer, Alice Wilce, John Dyer, Jason A. Roberts
Publikováno v:
European Medical Journal Nephrology, Vol 8, Iss 1, Pp 78-83 (2020)
Prolonged intermittent renal replacement therapy (PIRRT) is an emerging form of renal replacement therapy in critically ill patients, but dosing data for antibiotics such as amoxicillin and cefepime are scarce and limited. This case report describes
Externí odkaz:
https://doaj.org/article/7b43b9d108d84026890972b23644509e
Autor:
Craig, McDonald, Menino O, Cotta, Peter J, Little, Brett, McWhinney, Jacobus P, Ungerer, Jeffrey, Lipman, Jason A, Roberts
Publikováno v:
Minerva anestesiologica. 82(9)
β-lactam antibiotics may necessitate higher than licensed drug doses to achieve therapeutic exposures in critically ill patients. Therapeutic drug monitoring can be used to guide dosing so as to maximise therapeutic effect whilst reducing the likeli
Autor:
Katherine A, Barraclough, Nicole M, Isbel, David W, Johnson, Carmel M, Hawley, Katie J, Lee, Brett C, McWhinney, Jacobus P, Ungerer, Scott B, Campbell, Diana R, Leary, Christine E, Staatz
Publikováno v:
Nephrology (Carlton, Vic.). 17(3)
The aim of this study was to develop a limited sampling strategy (LSS) for the simultaneous estimation of exposure to tacrolimus, mycophenolic acid and unbound prednisolone in adult kidney transplant recipients.Tacrolimus, mycophenolic acid and unbou
Autor:
Andrew A, Udy, Julie M, Varghese, Mahdi, Altukroni, Scott, Briscoe, Brett C, McWhinney, Jacobus P, Ungerer, Jeffrey, Lipman, Jason A, Roberts
Publikováno v:
Chest. 142(1)
β-Lactams are routinely used as empirical therapy in critical illness, with extended concentrations above the minimum inhibitory concentration (MIC) of the infecting organism required for effective treatment. Changes in renal function in this settin