Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Jacobus P, Slabbert"'
Publikováno v:
Mathematical Medicine and Biology: A Journal of the IMA. 38:132-135
Autor:
Maryna de Kock, Jacobus P. Slabbert, Monique Engelbrecht, Charnay Cunningham, Xanthene Miles, Charlot Vandevoorde
Publikováno v:
Frontiers in Public Health
Frontiers in Public Health, Vol 9 (2021)
Frontiers in Public Health, Vol 9 (2021)
The number of proton therapy facilities and the clinical usage of high energy proton beams for cancer treatment has substantially increased over the last decade. This is mainly due to the superior dose distribution of proton beams resulting in a redu
Estimating the Relative Biological Effectiveness of Auger Electron Emitter 123I in Human Lymphocytes
Autor:
Daniel D. Rossouw, Charlot Vandevoorde, Richard T. Newman, Shankari Nair, Hein Fourie, P. Beukes, Jacobus P. Slabbert, Xanthene Miles, Jan Rijn Zeevaart
Publikováno v:
Frontiers in Physics, Vol 8 (2020)
Auger electron emitters are considered to be a promising strategy for targeted radionuclide therapy of metastatic diseases, given their high linear energy transfer (LET) and short range in tissue which could potentially limit normal tissue toxicity.
Corrigendum to: A proposed fractional-order Gompertz model and its application to tumour growth data
Publikováno v:
Mathematical Medicine and Biology: A Journal of the IMA. 35:273-277
Autor:
Emanuel Bahn, Michelle van Heerden, W. Shaw, K.N. Sachse, John Gueulette, Markus Alber, Jacobus P. Slabbert
Publikováno v:
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 150
Background and purpose Plasticity of the intestinal stem cell compartment in response to radiation injury is regulated by a stem cell niche. We present here the first experimental observations of a dose-volume effect of the intestinal stem cell niche
Autor:
Susanna Guatelli, Lachlan Chartier, S. Chiriotti, Charlot Vandevoorde, Dale A. Prokopovich, J.E. Symons, David Bolst, Emily Debrot, Jacobus P. Slabbert, M. De Saint-Hubert, E de Kock, Filip Vanhavere, Anatoly B. Rosenfeld, Jaime Nieto-Camero, P. Beukes, Linh T. Tran, Alessio Parisi
Publikováno v:
Physics in medicine and biology. 63(23)
With more patients receiving external beam radiation therapy with protons, it becomes increasingly important to refine the clinical understanding of the relative biological effectiveness (RBE) for dose delivered during treatment. Treatment planning s
Autor:
Emanuel Bahn, W. Shaw, Jacobus P. Slabbert, John Gueulette, Jürgen Debus, Michelle van Heerden, Markus Alber
Publikováno v:
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 129(3)
Background and purpose The high plasticity of the intestinal epithelium is maintained by a resilient reserve stem cell population, whose extent and biology are a matter of ongoing debate. The in vivo clonogenic assay (IVCA), presents a well establish
Autor:
J.E. Symons, Filip Vanhavere, Charlot Vandevoorde, S. Chiriotti, Alessio Parisi, M. De Saint-Hubert, E de Kock, P. Beukes, Jacobus P. Slabbert
Publikováno v:
Radiation protection dosimetry. 182(2)
Measurements of the dose equivalent at different distances from the isocenter of the proton therapy center at iThemba LABS were previously performed with a tissue-equivalent proportional counter (TEPC). These measurements showed that the scattered ra
Publikováno v:
International Journal of Particle Therapy. 2:37-43
Purpose: Currently, it is unclear if the variation in proton relative biological effectiveness (RBE) at different positions in the spread-out Bragg peak (SOBP) should be taken into account for medical applications. To date, the majority of studies ha
Autor:
Jacobus P. Slabbert, Anne Vral
Publikováno v:
Advanced Materials Research. 1084:559-566
When a cancer type proves to be radioresistant to treatment with X-rays, the use of neutrons may constitute therapeutic gain provided the cells are relatively sensitive to high-LET radiation. In this work studies with different tumor cell types are r