Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Jacobus J. Bosch"'
Autor:
Igor Radanovic, Naomi Klarenbeek, Robert Rissmann, Geert Jan Groeneveld, Emilie M. J. van Brummelen, Matthijs Moerland, Jacobus J. Bosch
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
AimTraditionally, early phase clinical trials in oncology have been performed in patients based on safety risk-benefit assessment. Therapeutic transition to immuno-oncology may open new opportunities for studies in healthy volunteers, which are condu
Externí odkaz:
https://doaj.org/article/05c5b23e725044ca9151f80660d82f26
Publikováno v:
Biology, Vol 12, Iss 5, p 738 (2023)
Uveal melanoma (UM) is a highly malignant tumor of the eye. Metastatic spread of UM occurs almost exclusively via blood vessels and is of tremendous interest, as half of the patients with uveal melanoma die of metastasis in the long run. The tumor mi
Externí odkaz:
https://doaj.org/article/60c568ad3be84fd9b45f858902ab352c
Autor:
Sebastian Schröder, Johannes Heck, Adrian Groh, Helge Frieling, Stefan Bleich, Kai G. Kahl, Jacobus J. Bosch, Benjamin Krichevsky, Martin Schulze-Westhoff
Publikováno v:
Brain Sciences, Vol 12, Iss 11, p 1424 (2022)
Apart from Alzheimer’s disease (AD), no biomarkers for the differential diagnosis of dementia have been established to date. Inflammatory processes contribute to the pathogenesis of dementia subtypes, e.g., AD or frontotemporal dementia (FTD). In t
Externí odkaz:
https://doaj.org/article/3ace2e96b11a4772a5c8a85842b5d4b5
Autor:
Ann-Katrin Menzner, Tanja Rottmar, Simon Voelkl, Jacobus J. Bosch, Dimitrios Mougiakakos, Andreas Mackensen, Yazid J. Resheq
Publikováno v:
Cancers, Vol 13, Iss 3, p 461 (2021)
Background and Aims: Induction of myeloid-derived suppressor cells (MDSC) is a critical step in immune cell evasion by different cancer types, including liver cancer. In the liver, hepatic stromal cells orchestrate induction of MDSCs, employing a mec
Externí odkaz:
https://doaj.org/article/718fe8de97384392ae83ac035c7a8623
Publikováno v:
Clinical & Experimental Ophthalmology.
Autor:
Jacobus J. Bosch, Andreas Mackensen, Ludwig M. Heindl, Bruce R. Ksander, Yazid J. Resheq, Barbara Bock, Jonas Sommer, Tanja Rottmar, Christian Buettner, Nasrin Refaian, Lukas John, Margarete M. Karg
Supplementary Figure from Midkine Promotes Metastasis and Therapeutic Resistance via mTOR/RPS6 in Uveal Melanoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ecba16dd55d3db99a9f40d6f105798f
https://doi.org/10.1158/1541-7786.22528151.v1
https://doi.org/10.1158/1541-7786.22528151.v1
Autor:
Jacobus J. Bosch, Andreas Mackensen, Ludwig M. Heindl, Bruce R. Ksander, Yazid J. Resheq, Barbara Bock, Jonas Sommer, Tanja Rottmar, Christian Buettner, Nasrin Refaian, Lukas John, Margarete M. Karg
Uveal melanoma is a rare form of melanoma that originates in the eye, exerts widespread therapeutic resistance, and displays an inherent propensity for hepatic metastases. Because metastatic disease is characterized by poor survival, there is an unme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::529f4cf8087ec86f8e4438a18161bb2f
https://doi.org/10.1158/1541-7786.c.6545630.v1
https://doi.org/10.1158/1541-7786.c.6545630.v1
Autor:
Dominique G. Stuijt, Vasileios Exadaktylos, Adriaan D. Bins, Jacobus J. Bosch, Martijn G.H. van Oijen
Publikováno v:
JCO Clinical Cancer Informatics, 6. American Society of Clinical Oncology
JCO clinical cancer informatics, 6. American Society of Clinical Oncology
Stuijt, D G, Exadaktylos, V, Bins, A D, Bosch, J J & van Oijen, M G H 2022, ' Potential Role of Smartphone-Based Passive Sensing in Remote Monitoring of Patients With Cancer ', JCO clinical cancer informatics, vol. 6, pp. e2200079 . https://doi.org/10.1200/CCI.22.00079
JCO clinical cancer informatics, 6. American Society of Clinical Oncology
Stuijt, D G, Exadaktylos, V, Bins, A D, Bosch, J J & van Oijen, M G H 2022, ' Potential Role of Smartphone-Based Passive Sensing in Remote Monitoring of Patients With Cancer ', JCO clinical cancer informatics, vol. 6, pp. e2200079 . https://doi.org/10.1200/CCI.22.00079
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::783661edc77c84f603a7ac26dc922f36
https://pure.amc.nl/en/publications/potential-role-of-smartphonebased-passive-sensing-in-remote-monitoring-of-patients-with-cancer(cd27f4a4-c034-4a85-bede-2e2f0890374e).html
https://pure.amc.nl/en/publications/potential-role-of-smartphonebased-passive-sensing-in-remote-monitoring-of-patients-with-cancer(cd27f4a4-c034-4a85-bede-2e2f0890374e).html
Autor:
Johannes Heck, Ann-Kathrin Rath, Katrin Wons, Carsten Schumacher, Anna Kutschenko, Nina Noltemeyer, Sarana Ulaganathan, Luca J. Voßiek, Hemme Hijma, Jeroen van Smeden, Christoph Schröder, Dirk O. Stichtenoth, Heiner Wedemeyer, Christoph Schindler, Jacobus J. Bosch
Publikováno v:
European journal of clinical pharmacologyReference. 78(11)
Purpose In the wake of the coronavirus disease 2019 (COVID-19) pandemic, support in clinical trials by students of human medicine and related disciplines has become of even greater importance than in pre-pandemic times. Documentation in clinical tria
Autor:
Thomas Clahsen, Karina Hadrian, Maria Notara, Simona L. Schlereth, Antonia Howaldt, Verena Prokosch, Thomas Volatier, Deniz Hos, Falk Schroedl, Alexandra Kaser-Eichberger, Ludwig M. Heindl, Philipp Steven, Jacobus J. Bosch, Alexander Steinkasserer, Alexander C. Rokohl, Hanhan Liu, Mert Mestanoglu, Hamid Kashkar, Björn Schumacher, Friedemann Kiefer, Stefan Schulte-Merker, Mario Matthaei, Yanhong Hou, Sonja Fassbender, Jonathan Jantsch, Wei Zhang, Philip Enders, Björn Bachmann, Felix Bock, Claus Cursiefen
Publikováno v:
Progress in Retinal and Eye Research. :101157