Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jacobus C. A. Van Meel"'
Autor:
Jacobus C. A. Van Meel, Kandace M. Matzek, Horst Lehmann, Michael Entzeroth, Volker Gladigau, Thomas Ebner, Jochen Schmid, Wolfgang Wienen, Ulrich Busch, Joachim Stangier, Joan Kempthorne-Rawson, Norbert Hauel
Publikováno v:
Cardiovascular Drug Reviews. 18:127-154
Telmisartan is a potent, long-lasting, nonpeptide antagonist of the angiotensin II type-1 (AT 1 ) receptor that is indicated for the treatment of essential hypertension. It selectively and insurmountably inhibits stimulation of the AT 1 receptor by a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32555483ecd44fe24096f459659a4a87
https://doi.org/10.1111/j.1527-3466.2000.tb00039.x
https://doi.org/10.1111/j.1527-3466.2000.tb00039.x
Autor:
Norbert Hauel, Wolfgang Wienen, Jacobus C. A. Van Meel, Berthold Narr, Kai M. Hasselbach, Uwe Ries, Helmut Wittneben, Gerhard Mihm, Michael Entzeroth
Publikováno v:
Journal of Medicinal Chemistry. 36:4040-4051
Starting from the recently reported nonpeptidic angiotensin II (AII) receptor antagonists DuP753 (1) and Exp 7711 (2), we have designed and investigated novel substituted benzimidazoles. Systemic variation of several substituents at the benzimidazole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6ead8ec4cc65146e06e80b97c72a90a
https://doi.org/10.1021/jm00077a007
https://doi.org/10.1021/jm00077a007