Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Jacobsen epoxidation"'
Publikováno v:
Pharmaceutical Fronts, Vol 03, Iss 03, Pp e113-e118 (2021)
Abstract This study reported an asymmetric synthesis of 1,2-limonene epoxides. The absolute stereochemistry was controlled by a Jacobsen epoxidation of cis-1,2-limonene epoxide (with diastereomeric excess of 98%) and trans-1,2-limonene epoxide (with
Externí odkaz:
https://doaj.org/article/e077b38b0bb142febb61e3030459d19f
Autor:
Mark Lautens, Egor M. Larin
Publikováno v:
Synfacts. 2019:0517
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f04fb17983c264e1b13153864f24081
https://doi.org/10.1055/s-0037-1611489
https://doi.org/10.1055/s-0037-1611489
Publikováno v:
Chemistry - A European Journal. 19:4532-4537
A concise and largely catalysis-based approach to the potent algal toxin polycavernoside A (1) is described that intercepts a late-stage intermediate of a previous total synthesis; from there on, this challenging target can be reached in a small numb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9c64cb99e08c0327a42dc3f6ee6f847
https://doi.org/10.1002/chem.201204551
https://doi.org/10.1002/chem.201204551
Autor:
Kiwan Jang, Gautam Dupati, Li-Juan Meng, B.V.D. Vijaykumar, Zhu-Bo Li, Hua Zuo, Dong-Soo Shin
Publikováno v:
Tetrahedron: Asymmetry. 23:1029-1037
With the aim of discovering new molecules with potassium channel activating properties, we have designed and synthesized derivatives with structural similarity to cromakalim, an important molecule which shows specific affinity toward potassium channe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::352d5eae50672cbc42d935c8e2d0a869
https://doi.org/10.1016/j.tetasy.2012.07.002
https://doi.org/10.1016/j.tetasy.2012.07.002
Autor:
S. S. Mandal, J. S. Yadav
Publikováno v:
Synlett. 2011:2803-2806
The enantioselective synthesis of bioactive butenolides isocladospolide B, cladospolide B, and cladospolide-C has been achieved from (S)-propylene oxide. Of the three stereogenic centers, the C-4/C-5 vic-diol was obtained using diastereo- and enantio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1fd979ee5ec2da741aafa08494daaef
https://doi.org/10.1055/s-0031-1289868
https://doi.org/10.1055/s-0031-1289868
Publikováno v:
Organic Letters. 11:4592-4595
It is proposed that facial selectivity in the Jacobsen epoxidation is determined by electrostatic and steric factors with a two-step pathway involving a carbocationic intermediate.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b274fbc30cc8ba25b4021619163cc48f
https://doi.org/10.1021/ol901859d
https://doi.org/10.1021/ol901859d
Autor:
Adrian Hall, Robert Haigh, Michael P. Coogan, Robert Leyshon Jenkins, Nicholas C. O. Tomkinson, C. Jones, Lisa D. Harris, David E. Hibbs
Publikováno v:
Tetrahedron. 59:7389-7395
A new approach to the rational design of Lewis acids based on face-face π-π interactions is described. The synthesis of two novel diols (-)(1R,3R)-2,2-dimethyl-1,2,3,4-tetrahydronaphthalene-1,3-diol (I) and (-)(1S,3R)-trans-2,2-dimethyl-1,2,3,4-tet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3101ecb1472b88ed1dcb77fe5bc8d6bf
https://doi.org/10.1016/s0040-4020(03)01127-x
https://doi.org/10.1016/s0040-4020(03)01127-x
Publikováno v:
Reactive and Functional Polymers. 53:103-112
Herein we report preliminary results on enantioselective epoxidations of styrene using molecular imprint polymers incorporating an analog of the Jacobsen epoxidation catalyst. We have synthesized molecular imprint polymers (MIPs) containing the pre-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c85253c507c0c9739ce06b8b610a7bda
https://doi.org/10.1016/s1381-5148(02)00166-9
https://doi.org/10.1016/s1381-5148(02)00166-9
Publikováno v:
Organic Letters. 4:3571-3574
[reaction: see text] Two methods have been developed for the synthesis of epoxide 36. The first uses (+)-pulegone 25 as an enantiopure starting material and introduces the requisite intricacy of target 22 in 12 operations. The second method employs a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c66fc79f4aaffd9693ce02bb8aae8e91
https://doi.org/10.1021/ol026377m
https://doi.org/10.1021/ol026377m
Autor:
Tien Nguyen
Publikováno v:
C&EN Global Enterprise. 95:9-9
Ketamine is a drug that has been administered as an anesthetic for more than 50 years. A decade ago, scientists found that a small dose of ketamine can also serve as a fast-acting antidepressant. Then last year, researchers discovered that ketamine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67047362e0342f11ce811e1dd83eeddb
https://doi.org/10.1021/cen-09538-scicon5
https://doi.org/10.1021/cen-09538-scicon5