Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jacobsen Thomas Amos"'
Autor:
Karin Sandager-Nielsen, Janus Schreiber Larsen, Dipak Vasantrao Amrutkar, Jacobsen Thomas Amos, Tino Dyhring
Publikováno v:
The Cerebellum. 19:265-274
Essential tremor (ET) is among the most prevalent neurological disorders and the most common cause of abnormal tremors. It is characterized by postural and action tremors ranging from 4 to 12 Hz. The treatments of choice for ET are propranolol and pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e47f6f623db1daf180edba3e0128d2d5
https://doi.org/10.1007/s12311-020-01106-w
https://doi.org/10.1007/s12311-020-01106-w
Autor:
Dorte Strøbæk, David R. Brown, Jacobsen Thomas Amos, Jessica Boddum, Dipak Vasantrao Amrutkar, Dean Carson, Palle Christophersen
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40292e4a0ce501ad910f8835679774cd
https://doi.org/10.1096/fasebj.2021.35.s1.05029
https://doi.org/10.1096/fasebj.2021.35.s1.05029
Autor:
Nils Brünner, Nicklas L. Roest, Jan Stenvang, Tore Bjerregaard Stage, Troels K Bergmann, Jacobsen Thomas Amos, Peter M. Vestlev, Palle Christophersen
Publikováno v:
Bergmann, T K, Stage, T B, Stenvang, J, Christophersen, P, Jacobsen, T A, Roest, N L, Vestlev, P M & Brunner, N 2020, ' Four phase 1 trials to evaluate the safety and pharmacokinetic profile of single and repeated dosing of SCO-101 in adult male and female volunteers ', Basic & Clinical Pharmacology & Toxicology, vol. 127, no. 4, pp. 329-337 . https://doi.org/10.1111/bcpt.13466
Bergmann, T K, Stage, T B, Stenvang, J, Christophersen, P, Jacobsen, T A, Roest, N L, Vestlev, P M & Brünner, N 2020, ' Four phase 1 trials to evaluate the safety and pharmacokinetic profile of single and repeated dosing of SCO-101 in adult male and female volunteers ', Basic & Clinical pharmacology & Toxicology, vol. 127, no. 4, pp. 329-337 . https://doi.org/10.1111/bcpt.13466
Basic & Clinical Pharmacology & Toxicology
Bergmann, T K, Stage, T B, Stenvang, J, Christophersen, P, Jacobsen, T A, Roest, N L, Vestlev, P M & Brünner, N 2020, ' Four phase 1 trials to evaluate the safety and pharmacokinetic profile of single and repeated dosing of SCO-101 in adult male and female volunteers ', Basic & Clinical pharmacology & Toxicology, vol. 127, no. 4, pp. 329-337 . https://doi.org/10.1111/bcpt.13466
Basic & Clinical Pharmacology & Toxicology
SCO-101 (Endovion) was discontinued 20 years ago as a new drug under development against sickle cell anaemia. Data from the phase 1 studies remained unpublished. New data indicate that SCO-101 might be efficacious as add-on therapy in cancer. Thus, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d41e0ff90bbb6f0ce3d727ddfe4da66
https://curis.ku.dk/portal/da/publications/four-phase-1-trials-to-evaluate-the-safety-and-pharmacokinetic-profile-of-single-and-repeated-dosing-of-sco101-in-adult-male-and-female-volunteers(e206d00c-8caf-49b6-af12-0b981d1cf13d).html
https://curis.ku.dk/portal/da/publications/four-phase-1-trials-to-evaluate-the-safety-and-pharmacokinetic-profile-of-single-and-repeated-dosing-of-sco101-in-adult-male-and-female-volunteers(e206d00c-8caf-49b6-af12-0b981d1cf13d).html
Autor:
Palle Christophersen, Jacobsen Thomas Amos, Dan Peters, Altair Brito dos Santos, Philip K. Ahring, Jessica Klein, Karin Sandager-Nielsen, Marloes van Hout, Kristi A. Kohlmeier, Anders A. Jensen, Siganya Thaneshwaran, Tino Dyhring, Dipak Vasantrao Amrutkar
Publikováno v:
Biochemical Pharmacology. 174:113786
Neuronal nicotinic acetylcholine receptors (nAChRs) are crucial mediators of central presynaptic, postsynaptic, and extrasynaptic signaling, and they are implicated in a range of CNS disorders. The numerous nAChR subtypes are differentially expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::869843e3bb718d143298dc648d94624c
https://doi.org/10.1016/j.bcp.2019.113786
https://doi.org/10.1016/j.bcp.2019.113786
Autor:
Jacobsen Thomas Amos, Martin S. Jørgensen, Patrik Rydberg, Anne-Marie Jacobsen, Kim G. Madsen, Lars Olsen
Publikováno v:
Angewandte Chemie. 125:1027-1031
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9141229c4f9a3b2fe4e9e41eb80f9669
https://doi.org/10.1002/ange.201206207
https://doi.org/10.1002/ange.201206207
Autor:
Marco Persico, Kim G. Madsen, Jacobsen Thomas Amos, Giuseppe Campiani, Jørgen Scheel-Krüger, Caterina Fattorusso, Sandra Gemma, Francesco Trotta, Vinod Kumar, Karin Sandager-Nielsen, Isabella Fiorini, Nausicaa Orteca, Stefania Butini, Egeria Guarino, Silvia Franceschini, Giuseppe Borrelli, Ettore Novellino
As a continuation of our efforts to develop innovative ligands for D(3), 5-HT(1A), and 5-HT(2A) receptors with low propensity to block hERG channels, we propose a series bishetero(homo)arylpiperazines 5a-m as novel and potent multifunctional ligands
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f094d43fed01475204cbbff0a468789e
http://hdl.handle.net/11588/374361
http://hdl.handle.net/11588/374361
Akademický článek
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Autor:
Barfod, Rasmus, Eriksen, Jette, Golding, Bernard T., Hammershøi, Anders, Jacobsen, Thomas Amos, Langkilde, Annette, Larsen, Sine, Mønsted, Ole, Sargeson, Alan M., SørensenPresent address: Center for Fundamental Research: Metal Structures in Four Dimensions, Henning Osholm, Mater
Publikováno v:
Dalton Transactions; 2005, Vol. 2005 Issue: 3 p491-500, 10p