Zobrazeno 1 - 10
of 1 102
pro vyhledávání: '"Jacobs-Lorena"'
Autor:
Marcelo Jacobs-Lorena, Sung-Jae Cha
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
Malaria is among the deadliest infectious diseases. Over 200 million annual clinical malaria cases are reported and more than half a million people, mostly children, die every year. The most advanced RTS,S/AS01 vaccine based on the P. falciparum circ
Externí odkaz:
https://doaj.org/article/e30304767ca24b1eb265a1f99fc7412a
MosAIC: An annotated collection of mosquito-associated bacteria with high-quality genome assemblies.
Autor:
Aidan Foo, Laura E Brettell, Holly L Nichols, UW-Madison Capstone in Microbiology Students, Miguel Medina Muñoz, Jessica A Lysne, Vishaal Dhokiya, Ananya F Hoque, Doug E Brackney, Eric P Caragata, Michael L Hutchinson, Marcelo Jacobs-Lorena, David J Lampe, Edwige Martin, Claire Valiente Moro, Michael Povelones, Sarah M Short, Blaire Steven, Jiannong Xu, Timothy D Paustian, Michelle R Rondon, Grant L Hughes, Kerri L Coon, Eva Heinz
Publikováno v:
PLoS Biology, Vol 22, Iss 11, p e3002897 (2024)
Mosquitoes transmit medically important human pathogens, including viruses like dengue virus and parasites such as Plasmodium spp., the causative agent of malaria. Mosquito microbiomes are critically important for the ability of mosquitoes to transmi
Externí odkaz:
https://doaj.org/article/dccd4b51fe7e44d1a2e4dec591992ea9
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
IntroductionLeishmaniasis comprises a complex group of diseases caused by protozoan parasites from the Leishmania genus, presenting a significant threat to human health. Infection starts by the release into the skin of metacyclic promastigote (MP) fo
Externí odkaz:
https://doaj.org/article/78acb6cea7c8431aa3719f91dcfa4eb7
Autor:
Sung-Jae Cha, Joel Vega-Rodriguez, Dingyin Tao, Heather M. Kudyba, Kelly Hanner, Marcelo Jacobs-Lorena
Publikováno v:
mBio, Vol 15, Iss 2 (2024)
ABSTRACT Plasmodium fertilization, an essential step for the development of the malaria parasite in the mosquito, is a prime target for blocking pathogen transmission. Using phage peptide display screening, we identified MG1, a peptide that binds to
Externí odkaz:
https://doaj.org/article/db04b044c8dc4d22bde02b008c644950
Akademický článek
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Akademický článek
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Publikováno v:
Malaria Journal, Vol 9, Iss 1, p 194 (2010)
Abstract Background Ookinete is the form of the malaria parasite that invades the mosquito midgut epithelium to initiate sporogony. Differentiation of ingested gametocytes into ookinetes in the mosquito midgut lumen and subsequent interaction with th
Externí odkaz:
https://doaj.org/article/e15eab80d35e4e8bafb8c1cbf4a49f03
Autor:
Tales V. Pascini, Yeong Je Jeong, Wei Huang, Zarna R. Pala, Juliana M. Sá, Michael B. Wells, Christopher Kizito, Brendan Sweeney, Thiago L. Alves e Silva, Deborah J. Andrew, Marcelo Jacobs-Lorena, Joel Vega-Rodríguez
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Plasmodium gametes and sporozoites activate surface-bound plasminogen to plasmin that degrades extracellular matrix barriers, therewith facilitating parasite motility in mosquitoes and mammalian hosts. To control malaria transmission, Pascini et al.
Externí odkaz:
https://doaj.org/article/6637f4de56264305b96cb1a12269a4bd
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
After transmission of Plasmodium sporozoites from infected mosquitoes, parasites first infect hepatocytes. Here, Cha et al. identify a sporozoite ligand (phospholipid scramblase) and the hepatocytic receptor (carbamoyl-phosphate synthetase 1) as rele
Externí odkaz:
https://doaj.org/article/d8ed248f9c5e47a38f04d306b2a1b9da
Autor:
Cha, Sung-Jae, Jacobs-Lorena, Marcelo
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2020 Feb . 117(8), 3898-3900.
Externí odkaz:
https://www.jstor.org/stable/26929033