Mycophenolate and azathioprine efficacy in interstitial lung disease: a systematic review and meta-analysis

Autor: Sally Singh, Mark Jones, Michael Kreuter, Maria Molina-Molina, Imre Noth, Andrew Wilson, Martin Brutsche, Naftali Kaminski, Gary M Hunninghake, Michael Keane, Nazia Chaudhuri, Ian Forrest, Bruno Crestani, Fernando J Martinez, Mohsen Sadatsafavi, Luca Richeldi, Antje Prasse, Fasihul Khan, Iain Stewart, Steve Jones, Gisli Jenkins, Gauri Saini, David Turner, Killian Hurley, Lucilla Piccari, Andrew Palmer, Joseph A Lasky, Simon Hart, Joyce Lee, Anthony Gordon, John Blaikley, Kirsty Hett, Helmut Prosch, Elisabeth Bendstrup, Christopher Huntley, Helen Parfrey, Huzaifa Adamali, Paul Beirne, Stephen Bianchi, George Chalmers, Sophie Fletcher, Peter George, Michael Gibbons, Mark Spears, Laura Fabbri, Felix Chua, Michael Henry, Cormac McCarthy, Sabrina Paganoni, Joseph Jacob, Mark Toshner, Bibek Gooptu, Andrew Briggs, Philip L Molyneaux, Athol Wells, Charlotte Summers, Leticia Kawano-Dourado, Ian Glaspole, Melanie Quintana, Christopher J Ryerson, Paolo Spagnolo, Francesco Bonella, Carisi Anne Polanczyk, Anjali Crawshaw, Laurence Pearmain, Avinash Anil Nair, Raphaël Borie, Alexandre Biasi Cavalcanti, Emanuela Falaschetti, Jonathan Chung, James Eaden, Kate Johnson, Shaney Barratt, Chris Ryerson, Juergen Behr, Andreas Guenther, Nik Hirani, Karin Storrer, Deepak Talwar, Claudia Ravaglia, Katerina Antoniou, Sara Freitas, Carlo Vancheri, Laura Price, Amanda Goodwin, Daniel Chambers, Gunnar Gudmundsson, Roger Lewis, Ingrid Cox, Anne Holland, Erica Farrand, Argyrios Tzouvelekis, Rui Rolo, Duncan Richards, Larissa Schwarzkopf, Sabina Guler, Devesh Dhasmana, Claudia Valenzuela, John S Kim, Louise Crowley, Lisa Watson, Amanda Bravery, Elisabetta Balestro, Wendy Adams, Francesco Lombardi, Ali Mojibian, Ana Etges, Ana Sousa Marcelino Boshoff, Anne Bergeron Anna-MariaHoffmann-Vold, Athina Trachalaki, Barbara Wendelberger, Bhavika Kaul Ben Hope-Gill, Bruno Baldi, Carlos Robalo, Chris Grainge, Christophe von Garnier, Conal Hayton, Dapeng Wang, Daphne Bablis, David Thicket, Deji Adegunsoye, Devaraj Anand, Dhruv Parek, Diane Griffiths, Eliana Santucci, Eliza Tsitoura, Emma Karlsen, Ena Gupta, Harold Collard, Hernan Fainberg, Iazsmin Bauer-Ventura, Irina Strambu, Jacobo Sellares, Janet Johnston, Jeff Swigris, Karina Negrelli, Katarzyna Lewandowska, Katrin Hostettler, Kerri Johannson, Liam Galvin, Lisa G. Spencer, Manuela Funke Chambour, Marlies Wijsenbeek-Lourens, Martina Vasakova, Milena Man Iuliu Hatieganu, Nick Weatherley, Ovidiu Fira Mladinescu Victor Babes, Peter Bryce, Pilar Rivera Ortega, Radu Crisan-Dabija, Rahul Maida, Sara Piciucchi, Shama Malik, Simone Dal Corso, Stefan Stanel

Publikováno v: BMJ Open Respiratory Research, Vol 11, Iss 1 (2024)

Objectives Mycophenolate mofetil (MMF) and azathioprine (AZA) are immunomodulatory treatments in interstitial lung disease (ILD). This systematic review aimed to evaluate the efficacy of MMF or AZA on pulmonary function in ILD.Design Population inclu

Externí odkaz: https://doaj.org/article/2ac47dada7d648a4a2a2a9b8b2f6ab10

Exploring the Interplay between Cellular Senescence, Immunity, and Fibrosing Interstitial Lung Diseases: Challenges and Opportunities

Autor: Fernanda Hernandez-Gonzalez, Federico Pietrocola, Paolo Cameli, Elena Bargagli, Sergio Prieto-González, Tamara Cruz, Nuria Mendoza, Mauricio Rojas, Manuel Serrano, Alvar Agustí, Rosa Faner, Jose A. Gómez-Puerta, Jacobo Sellares

Publikováno v: International Journal of Molecular Sciences, Vol 25, Iss 14, p 7554 (2024)

Fibrosing interstitial lung diseases (ILDs) are characterized by the gradual and irreversible accumulation of scar tissue in the lung parenchyma. The role of the immune response in the pathogenesis of pulmonary fibrosis remains unclear. In recent yea

Externí odkaz: https://doaj.org/article/42bc7d13f48f4e13a5a56decf37a6896

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SARS-CoV-2 T-cell response in COVID-19 convalescent patients with and without lung sequelae

Autor: Tamara Cruz, Núria Mendoza, Lídia Perea, Núria Albacar, Azucena Gonzalez, Fernanda Hernandez-Gonzalez, Manel Juan, Alvar Agustí, Jacobo Sellares, Oriol Sibila, Rosa Faner

Publikováno v: ERJ Open Research, Vol 8, Iss 1 (2022)

Externí odkaz: https://doaj.org/article/76d25db375bb49a99f201e5edf930317

Characteristics of lung cancer among patients with idiopathic pulmonary fibrosis and interstitial lung disease – analysis of institutional and population data

Autor: Joo Heung Yoon, Mehdi Nouraie, Xiaoping Chen, Richard H Zou, Jacobo Sellares, Kristen L Veraldi, Jared Chiarchiaro, Kathleen Lindell, David O Wilson, Naftali Kaminski, Timothy Burns, Humberto Trejo Bittar, Samuel Yousem, Kevin Gibson, Daniel J Kass

Publikováno v: Respiratory Research, Vol 19, Iss 1, Pp 1-10 (2018)

Abstract Background Lung Cancer is occasionally observed in patients with Idiopathic Pulmonary Fibrosis (IPF). We sought to describe the epidemiologic and clinical characteristics of lung cancer for patients with IPF and other interstitial lung disea

Externí odkaz: https://doaj.org/article/d9e31fe0e7ab4311a2b9beed83487a19