Výsledky vyhledávání - "Jacoba Flier"

The Neuroprotective Antioxidant α-lipoic Acid Induces Detoxication Enzymes in Cultured Astroglial Cells

Autor: Cornelis A. M. Jongenelen, Benjamin Drukarch, Freek L Van Muiswinkel, Jacoba Flier

Publikováno v: Free Radical Research. 36:695-699

alpha-Lipoic acid (LA), an antioxidant with broad neuroprotective capacity, is thought to act by scavenging reactive oxygen species and stimulation of glutathione synthesis. LA shows structural resemblance to dithiolethiones, like anethole dithioleth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41584b0eefd2c29f021aa23acbfdd678
https://doi.org/10.1080/10715760290029155

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Differential expression of CXCR3 targeting chemokines CXCL10, CXCL9, and CXCL11 in different types of skin inflammation

Autor: Cees Nieboer, Jacoba Flier, Peter J. van Beek, T.J. Stoof, Rein Willemze, D.M. Boorsma, Cornelis P. Tensen

Publikováno v: The Journal of Pathology. 194:398-405

Recruitment of activated T-cells to the skin is a common feature in a wide variety of inflammatory skin diseases. As CXCR3 activating chemokines CXCL10 (IP-10), CXCL9 (Mig), and CXCL11 (IP-9/I-TAC) specifically attract activated T-cells, this study a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d80a5a80d1cfcc232f3b253b3e1e8545
https://doi.org/10.1002/1096-9896(200108)194:4<397::aid-path899>3.0.co

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The antipsoriatic drug dimethylfumarate strongly suppresses chemokine production in human keratinocytes and peripheral blood mononuclear cells

Autor: D.M. Boorsma, Cornelis P. Tensen, Cees Nieboer, S. Sampat, T.J. Stoof, Jacoba Flier

Publikováno v: British Journal of Dermatology. 144:1114-1120

BACKGROUND The effectiveness of systemic treatment of psoriasis with fumaric acid esters has been proven, but their mode of action at the cellular and molecular level has not yet been fully elucidated. OBJECTIVES To study the effect of dimethylfumara

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d93b4b351b574504067c9879c3f53a4
https://doi.org/10.1046/j.1365-2133.2001.04220.x

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The CXCR3 Activating Chemokines IP-10, Mig, and IP-9 are Expressed in Allergic but not in Irritant Patch Test Reactions

Autor: Rein Willemze, Jacoba Flier, D.M. Boorsma, Peter J. van Beek, Rik J. Scheper, Cornelis P. Tensen, Derk P. Bruynzeel, T.J. Stoof

Publikováno v: Journal of Investigative Dermatology. 113(4):574-578

Differentiation between allergic and irritant contact dermatitis reactions is difficult, as both inflammatory diseases are clinically, histologically, and immunohistologically very similar. Previous studies in mice revealed that the chemokine IP-10 i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6196d937013d602a354ecc58e870eac5

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IP-10 mRNA EXPRESSION IN CULTURED KERATINOCYTES IS SUPPRESSED BY INHIBITION OF PROTEIN KINASE-C AND TYROSINE KINASE AND ELEVATION OF cAMP

Autor: Edward N van den Brink, Rein Willemze, Jacoba Flier, D.M. Boorsma, Shakun Sampat, Hugo L Walg, Cornelis P. Tensen, T.J. Stoof

Publikováno v: Cytokine. 11:469-475

IFN-gamma-inducible protein-10 (IP-10) is a chemokine, which plays an important role in mediating inflammation by attracting activated T cells, and it has been demonstrated in inflammatory skin diseases and cutaneous T cell lymphomas. Keratinocytes c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31bc4b6d51e8ae0cc6a62cbeef741a8a
https://doi.org/10.1006/cyto.1998.0463

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Genomic organization, sequence and transcriptional regulation of the human CXCL 11 gene

Autor: D.M. Boorsma, Cornelis P. Tensen, Jacoba Flier, Sharita S. Rampersad, Rein Willemze, Shakun C. Sampat-Sardjoepersad, Rik J. Scheper

Publikováno v: Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1446:167-172

CXCL 11, encoded by the cDNA sequences designated β-R1, H-174, or I-TAC, is a CXC chemokine ligand for CXCR3 and assumed to be involved in inflammatory diseases characterized by the presence of activated T-cells. We here describe the genomic organiz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::28798fbfe731e99e106c7a66433c6737
https://doi.org/10.1016/s0167-4781(99)00084-6

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Increased CCL27-CCR10 expression in allergic contact dermatitis: implications for local skin memory

Autor: Heleen Moed, Maureen J. Jonker, Rik J. Scheper, Susan Gibbs, Derk P. Bruynzeel, Thomas Rustemeyer, D.M. Boorsma, Cornelis P. Tensen, Jacoba Flier, T.J. Stoof, B. Mary E. von Blomberg

Publikováno v: Journal of Pathology, 204(1), 39-46. John Wiley and Sons Ltd
Moed, H, Boorsma, D M, Tensen, C P, Flier, J, Jonker, M J, Stoof, T J, von Blomberg-van der Flier, B M E, Bruynzeel, D P, Scheper, R J, Rustemeyer, T & Gibbs, S 2004, ' Increased CCL27-CCR10 expression in allergic contact dermatitis: implications for local skin memory. ', Journal of Pathology, vol. 204, no. 1, pp. 39-46 . https://doi.org/10.1002/path.1619

Allergic contact dermatitis (ACD) is a T-cell-mediated disease in which expression of a distinct repertoire of chemokines results in the recruitment of effector T cells into the skin. While it is becoming clear which chemokines and receptors determin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba59597599f5782708475a630cb1fe77
https://research.vumc.nl/en/publications/4550df38-7f7e-406a-bcad-c4954a834b24

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