Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Jacob W. Myerson"'
Autor:
Laura T. Ferguson, Xiaonan Ma, Jacob W. Myerson, Jichuan Wu, Patrick M. Glassman, Marco E. Zamora, Elizabeth D. Hood, Michael Zaleski, Mengwen Shen, Eno-Obong Essien, Vladimir V. Shuvaev, Jacob S. Brenner
Publikováno v:
Advanced NanoBiomed Research, Vol 3, Iss 3, Pp n/a-n/a (2023)
Diseases of the pulmonary alveolus, such as pulmonary fibrosis, are leading causes of morbidity and mortality, but exceedingly few drugs are developed for them. A major reason for this gap is that after inhalation, drugs are quickly whisked away from
Externí odkaz:
https://doaj.org/article/eb489d494be74c0a89082fbe3a8a2bcc
Autor:
Kathryn M. Rubey, Alexander R. Mukhitov, Jia Nong, Jichuan Wu, Vera P. Krymskaya, Jacob W. Myerson, G. Scott Worthen, Jacob S. Brenner
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Despite the power of antibiotics, bacterial infections remain a major killer, due to antibiotic resistance and hosts with dysregulated immune systems. We and others have been developing drug-loaded nanoparticles that home to the sites of infection an
Externí odkaz:
https://doaj.org/article/e813c9186b2f4af98701330fc592cef8
Autor:
Livia P. Mendes, Kobra Rostamizadeh, Kandace Gollomp, Jacob W. Myerson, Oscar A. Marcos-Contreras, Marco Zamora, Ed Luther, Jacob S. Brenner, Nina Filipczak, Xiang Li, Vladimir P. Torchilin
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
Neutrophils can release DNA and granular cytoplasmic proteins that form smooth filaments of stacked nucleosomes (NS). These structures, called neutrophil extracellular traps (NETs), are involved in multiple pathological processes, and NET formation a
Externí odkaz:
https://doaj.org/article/8d2f118ff53140ff9423e891e3e3516f
Autor:
Jacob S. Brenner, Daniel C. Pan, Jacob W. Myerson, Oscar A. Marcos-Contreras, Carlos H. Villa, Priyal Patel, Hugh Hekierski, Shampa Chatterjee, Jian-Qin Tao, Hamideh Parhiz, Kartik Bhamidipati, Thomas G. Uhler, Elizabeth D. Hood, Raisa Yu. Kiseleva, Vladimir S. Shuvaev, Tea Shuvaeva, Makan Khoshnejad, Ian Johnston, Jason V. Gregory, Joerg Lahann, Tao Wang, Edward Cantu, William M. Armstead, Samir Mitragotri, Vladimir Muzykantov
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Unwanted uptake in the liver and limited accumulation in target organs is a major obstacle to targeted drug delivery. Here, the authors report on the hitchhiking of nanocarriers on red blood cells and the targeted upstream delivery to different targe
Externí odkaz:
https://doaj.org/article/362e0eed733347a8aa0df110774ccc31
Autor:
Sahily Reyes-Esteves, Jia Nong, Patrick M. Glassman, Serena Omo-Lamai, Sarah Ohashi, Jacob W. Myerson, Marco E. Zamora, Xiaonan Ma, Scott E. Kasner, Lauren Sansing, Vladimir R. Muzykantov, Oscar A. Marcos-Contreras, Jacob S. Brenner
Publikováno v:
Journal of Controlled Release. 356:185-195
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abe5fcd7fc52d1f9d756745d910ff08c
https://doi.org/10.1016/j.jconrel.2023.02.037
https://doi.org/10.1016/j.jconrel.2023.02.037
Autor:
Patrick M. Glassman, Carlos H. Villa, Oscar A. Marcos-Contreras, Elizabeth D. Hood, Landis R. Walsh, Colin F. Greineder, Jacob W. Myerson, Tea Shuvaeva, Laura Puentes, Jacob S. Brenner, Don L. Siegel, Vladimir R. Muzykantov
Publikováno v:
Bioconjugate Chemistry. 33:1286-1294
Engineering drug delivery systems for prolonged pharmacokinetics (PK) has been an ongoing pursuit for nearly 50 years. The gold standard for PK enhancement is the coating of nanoparticles with polymers, namely polyethylene glycol (PEGylation), which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::737d26eb53b8ea6c87a08ea2e73fb890
https://doi.org/10.1021/acs.bioconjchem.2c00196
https://doi.org/10.1021/acs.bioconjchem.2c00196
Autor:
Hamideh Parhiz, Jacob S. Brenner, Priyal N. Patel, Tyler E. Papp, Hamna Shahnawaz, Qin Li, Ruiqi Shi, Marco E. Zamora, Amir Yadegari, Oscar A. Marcos-Contreras, Ambika Natesan, Norbert Pardi, Vladimir V. Shuvaev, Raisa Kiseleva, Jacob W. Myerson, Thomas Uhler, Rachel S. Riley, Xuexiang Han, Michael J. Mitchell, Kieu Lam, James Heyes, Drew Weissman, Vladimir R. Muzykantov
Publikováno v:
Journal of Controlled Release
Current nucleoside-modified RNA lipid nanoparticle (modmRNA-LNP) technology has successfully paved the way for the highest clinical efficacy data from next-generation vaccinations against SARS-CoV-2 during the COVID-19 pandemic. However, such modmRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b3bb75c1bfa179ab971c5c700797c73
https://doi.org/10.1016/j.jconrel.2021.12.027
https://doi.org/10.1016/j.jconrel.2021.12.027
Autor:
Briana Macedo, Manthan Patel, Michael H. Zaleski, Parth Mody, Xiaonan Ma, Patrick Mei, Jacob W. Myerson, Jacob S. Brenner, Patrick M. Glassman
Publikováno v:
International Journal of Pharmaceutics. 639:122951
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a440c902f83d02b424255ca7fcece4b
https://doi.org/10.1016/j.ijpharm.2023.122951
https://doi.org/10.1016/j.ijpharm.2023.122951
Autor:
Laura T. Ferguson, Elizabeth D. Hood, Tea Shuvaeva, Vladimir V. Shuvaev, Maria C. Basil, Zhicheng Wang, Jia Nong, Xiaonan Ma, Jichuan Wu, Jacob W. Myerson, Oscar A. Marcos-Contreras, Jeremy Katzen, Justine M. Carl, Edward E. Morrisey, Edward Cantu, Carlos H. Villa, Samir Mitragotri, Vladimir R. Muzykantov, Jacob S. Brenner
Publikováno v:
ACS Nano
A long-standing goal of nanomedicine is to improve a drug’s benefit by loading it into a nanocarrier that homes solely to a specific target cell and organ. Unfortunately, nanocarriers usually end up with only a small percentage of the injected dose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27890969e38ca28d17e3ff872c3569de
https://europepmc.org/articles/PMC9339245/
https://europepmc.org/articles/PMC9339245/
Autor:
Weihang Ji, Libin Zhang, Sheiliza Carmali, Richard R. Koepsel, Jill D. Andersen, Alan J. Russell, Vladimir R. Muzykantov, Paige N. Smith, Jacob W. Myerson, Stefanie L. Baker
Publikováno v:
Acta Biomaterialia. 101:422-435
The global and economic success of immunoglobulin-based therapeutics in treating a wide range of diseases has heightened the need to further enhance their efficacy and lifetime while diminishing deleterious side effects. The three most ubiquitous cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9603a2e3bcde91afdc54f9fed9abeb60
https://doi.org/10.1016/j.actbio.2019.10.027
https://doi.org/10.1016/j.actbio.2019.10.027