Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jacob W Gauer"'
Autor:
Michael E Fealey, Jacob W Gauer, Sarah C Kempka, Katie Miller, Kamakshi Nayak, R Bryan Sutton, Anne Hinderliter
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46748 (2012)
Synaptotagmin I (Syt I) is a vesicle-localized protein implicated in sensing the calcium influx that triggers fast synchronous release of neurotransmitter. How Syt I utilizes its two C2 domains to integrate signals and mediate neurotransmission has c
Externí odkaz:
https://doaj.org/article/636971064df94cd5aafbb4edaf9752e4
Autor:
Anne Hinderliter, Samantha R. Jaworski, Anne M. Rice, Anika Rannikko, Barry R. Lentz, Kristofer J. Knutson, Jacob W. Gauer
Publikováno v:
Biophysical Journal. 104(11):2437-2447
Isothermal titration calorimetry was used to characterize the binding of calcium ion (Ca2+) and phospholipid to the peripheral membrane-binding protein annexin a5. The phospholipid was a binary mixture of a neutral and an acidic phospholipid, specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d71aaea141fcc0af5689cc603ac4c83f
Autor:
Meghan Hoffman, Brittney Slavik, Kelsey Pautz, Tyson Sievers, Katie Abata, Jessica Malone, Tyler Fadness, Jami L. Sloan, Andrew Tuthill, Becca Bartley, Derek Ecklund, Aaron Kuefler, Ryan Galloway, Stephanie Keller, Barite Tusa, Jacob W. Gauer, Brendan Kiefer, Kendelle Olson, Amy Ward, Shannon Detienne, Victoria Caskey, Anne Hildebrandt, Cody Rengo, Sean Mitchell, Po Nien Lu, Joshua Fulton, Peter Timinski, Benjamin Christianson, Nathan M. Lewis, Michael Flatten, David Hasbargen, Cassandra L. Dillon, Shayna Olsen, Pamela Nelson, Michael Hagler, Nicholas Taurinskas, Patrick Tandberg, Michelle Nemec, Matthew Joyal, Emily Stromquist, Jaclyn Hillesheim, Raymond Erickson, Mark Thiele, Eric Bachelder, Nadejda Bozadjieva, Candice Smrekar, Andrea Hammer, Jacob King, Jennifer O. Liang, Chelsey Mickolichek, Kelsey Pieper, Bradley Uher, Nicholas Fetter, Rami Jubran, Michelle Remackel, Alex J. Larson, Derek Kent, David Eckwright, Sonja Iverson, Jonathan Hovey, Luke D. Wilson, Brandon Heckmann, Jaime Sekenski, Michael E. Fealey, Nathan Young
Publikováno v:
Zebrafish. 8(4)
As part of an upper level undergraduate developmental biology course at the University of Minnesota Duluth, we developed a unit in which students carried out original research as part of a cooperative class project. Students had the opportunity to ga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff48640c8f9bd49cbe61eb3b7a1159e6
https://pubmed.ncbi.nlm.nih.gov/22181662
https://pubmed.ncbi.nlm.nih.gov/22181662
Autor:
Katie Miller, Jacob W. Gauer, R. Bryan Sutton, Anne Hinderliter, Greg Gillispie, Sarah C. Kempka
Publikováno v:
Biophysical Journal. 100(3)
Synaptotagmin I is a calcium ion sensor involved in neurotransmitter release. When a neuron is stimulated by an action potential, an influx of calcium ion occurs causing the synaptic vesicle to fuse with the membrane, releasing the neurotransmitter i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af6d0394bada06f380366fd24afdd559
Autor:
R. Bryan Sutton, Anne Hinderliter, Jacob W. Gauer, Troy Hendrickson, Ryan Mahling, K. Jean Lohese, Michael E. Fealey
Publikováno v:
Biophysical Journal. 106(2):528a-529a
Synaptotagmin I is a protein involved in the final steps of neurotransmitter release assisting in the fusion of vesicles with the plasma membrane of nerve cells. The synaptotagmin protein consists of a single transmembrane region connected to two C2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91ef3f2da2510646063c3e88c4a162c2
Publikováno v:
Biophysical Journal. 98(3)
Exocytosis of neurotransmitters is triggered by the initial influx of Ca2+. Synaptotagmin I is known to bind Ca2+ and the phospholipid membrane to modulate this process. The exact mechanism for this information transduction, however, is not well know
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa41c8811ac5368f2c40a08201510feb
Autor:
Jacob W. Gauer, Anne Hinderliter, Erin D. Sheets, Kanika Vats, Andrew Houghton, Jesse Murphy, Kristofer J. Knutson
Publikováno v:
Biophysical Journal. 96(3)
Protein-membrane interactions are a vital mechanism of propagating signals both across the membrane and between cells. One method of signal propagation is the formation of lipid microdomains that allow the preferential clustering of specific lipid ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e95f7becc8a6d61795f06668434a01
Publikováno v:
Biophysical Journal. 100(3):510a-511a
Thermodynamic parameters capture the overall contribution to a system's energetics. In the case of binding proteins, such as Synaptotagmin I, ascertaining the overall magnitude of the interactions within the protein is the first step toward addressin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::676adc9e49dba2acd30a1a86f81e1784
Publikováno v:
Biophysical Journal. 104:102a
Through regular use the plasma membrane or, sarcolemma, of myocytes undergoes a number of physical disruptions which in order for the cell to survive must be effectively and rapidly repaired. Currently, it is believed that small lesions in the cellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bd0879d9f781d15f8020c8fb9aad709
https://doi.org/10.1016/j.bpj.2012.11.599
https://doi.org/10.1016/j.bpj.2012.11.599
Autor:
Sarah C. Kempka, R. Bryan Sutton, Anne Hinderliter, Jacob W. Gauer, Kamakshi Nayak, Katie Miller, Michael E. Fealey
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46748 (2012)
PLoS ONE
PLoS ONE
Synaptotagmin I (Syt I) is a vesicle-localized protein implicated in sensing the calcium influx that triggers fast synchronous release of neurotransmitter. How Syt I utilizes its two C2 domains to integrate signals and mediate neurotransmission has c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef3096b152d7390b8eafc9cd5f999b80
https://doi.org/10.1371/journal.pone.0046748
https://doi.org/10.1371/journal.pone.0046748