Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jacob W Fleming"'
Autor:
Alec ST Smith, Shawn M Luttrell, Jean-Baptiste Dupont, Kevin Gray, Daniel Lih, Jacob W Fleming, Nathan J Cunningham, Sofia Jepson, Jennifer Hesson, Julie Mathieu, Lisa Maves, Bonnie J Berry, Elliot C Fisher, Nathan J Sniadecki, Nicholas A Geisse, David L Mack
Publikováno v:
Journal of Tissue Engineering, Vol 13 (2022)
Engineered muscle tissues represent powerful tools for examining tissue level contractile properties of skeletal muscle. However, limitations in the throughput associated with standard analysis methods limit their utility for longitudinal study, high
Externí odkaz:
https://doaj.org/article/565ad4a21c544b2c9f25e7a2e203b886
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Investigations of the human neuromuscular junction (NMJ) have predominately utilised experimental animals, model organisms, or monolayer cell cultures that fail to represent the physiological complexity of the synapse. Consequently, there re
Externí odkaz:
https://doaj.org/article/4e4e49a1611143bc96fb271b7731c6bd
Autor:
Andrew J. Capel, Rowan P. Rimington, Jacob W. Fleming, Darren J. Player, Luke A. Baker, Mark C. Turner, Julia M. Jones, Neil R. W. Martin, Richard A. Ferguson, Vivek C. Mudera, Mark P. Lewis
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 7 (2019)
Tissue engineered skeletal muscle allows investigation of the cellular and molecular mechanisms that regulate skeletal muscle pathology. The fabricated model must resemble characteristics of in vivo tissue and incorporate cost-effective and high cont
Externí odkaz:
https://doaj.org/article/c9f92cc68de04d449665ecde0d79a6de
Autor:
Andrew J. Capel, Kathryn W. Aguilar‐Agon, Neil R.W. Martin, Darren J. Player, Jacob W. Fleming, Mark P. Lewis
Publikováno v:
Journal of Muscle Research and Cell Motility
Skeletal muscle atrophy as a consequence of acute and chronic illness, immobilisation, muscular dystrophies and aging, leads to severe muscle weakness, inactivity and increased mortality. Mechanical loading is thought to be the primary driver for ske
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9456ec5d519f173c5c3bd829f77f7dd5
http://europepmc.org/articles/PMC8332579
http://europepmc.org/articles/PMC8332579
Autor:
Chris Molloy, Jacob E Mandel, David P. Duncan, Geogy Vatakencherry, Muhammad Noor, N. Gutta, Jacob W. Fleming, Mina S. Makary
Publikováno v:
Journal of Vascular and Interventional Radiology. 31:176-178
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a815f3469bd1315d6b21553929787b
https://doi.org/10.1016/j.jvir.2019.09.008
https://doi.org/10.1016/j.jvir.2019.09.008
Autor:
Rowan P. Rimington, Mark C. Turner, Leanne Hodson, Andrew J. Capel, Neil R.W. Martin, Jacob W. Fleming, Mark P. Lewis
Publikováno v:
Journal of cellular physiologyREFERENCES. 236(10)
Fatty acids (FA) exert physiological and pathophysiological effects leading to changes in skeletal muscle metabolism and function, however, in vitro models to investigate these changes are limited. These experiments sought to establish the effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99412ddb37d411d833e16bf661a6b4cb
https://pubmed.ncbi.nlm.nih.gov/33738797
https://pubmed.ncbi.nlm.nih.gov/33738797
Autor:
Steven D. R. Christie, Jacob W. Fleming, H.C. Hemaka Bandulasena, Richard J. Bibb, Andrew J. Capel, Kerry F Chaplin, Rowan P. Rimington, Mark P. Lewis
Publikováno v:
ACS biomaterials scienceengineering. 5(10)
Bioengineered skeletal muscle tissues benefit from dynamic culture environments which facilitate the appropriate provision of nutrients and removal of cellular waste products. Biologically compatible perfusion systems hold the potential to enhance th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ad0cf2acbb2a27bd3e3b061ba60e669
https://pubmed.ncbi.nlm.nih.gov/33464072
https://pubmed.ncbi.nlm.nih.gov/33464072
Autor:
Andrew J. Capel, Owen G Davies, Rowan P. Rimington, Nicolette C. Bishop, Amber N. Leonard, Jacob W. Fleming, Mark P. Lewis, Patrick C. Wheeler
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-16 (2020)
BMC Biology
BMC Biology
BackgroundSkeletal muscle (SkM) regenerates following injury, replacing damaged tissue with high fidelity. However, in serious injuries, non-regenerative defects leave patients with loss of function, increased re-injury risk and often chronic pain. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11d01866a47d2807577db8bed253159a
https://doi.org/10.1186/s12915-020-00884-3
https://doi.org/10.1186/s12915-020-00884-3
Autor:
Andrew J. Capel, Rowan P. Rimington, Patrick C. Wheeler, Jacob W. Fleming, Mark P. Lewis, Owen G Davies
Skeletal muscle (SkM) regenerates following injury, replacing damaged tissue with high fidelity. However, in serious injuries non-regenerative defects leave patients with loss of function, increased re-injury risk and often chronic pain. Progress in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::002179691a08c1d293e59ebfc1349546
https://doi.org/10.1101/2020.05.04.076828
https://doi.org/10.1101/2020.05.04.076828
Autor:
Mark C. Turner, Jacob W. Fleming, Rowan P. Rimington, Neil R.W. Martin, Andrew J. Capel, Mark P. Lewis, Leanne Hodson
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4aedc5bc1cd8cd1bf67860d285598434
https://doi.org/10.1530/endoabs.65.oc1.3
https://doi.org/10.1530/endoabs.65.oc1.3