Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jacob W, Bettencourt"'
Autor:
Louis Dagneaux, Afton K. Limberg, Aaron R. Owen, Jacob W. Bettencourt, Amel Dudakovic, Banu Bayram, Naomi M. Gades, Joaquin Sanchez-Sotelo, Daniel J. Berry, Andre van Wijnen, Mark E. Morrey, Matthew P. Abdel
Publikováno v:
Bone & Joint Research, Vol 12, Iss 1, Pp 58-71 (2023)
AimsAs has been shown in larger animal models, knee immobilization can lead to arthrofibrotic phenotypes. Our study included 168 C57BL/6J female mice, with 24 serving as controls, and 144 undergoing a knee procedure to induce a contracture without os
Externí odkaz:
https://doaj.org/article/de744dfec56c45fd9615de3aba6bd83c
Autor:
Afton K. Limberg, Christopher G. Salib, Meagan E. Tibbo, Juan S. Vargas-Hernandez, Jacob W. Bettencourt, Banu Bayram, Charlotte E. Berry, Amel Dudakovic, Brad Bolon, Andre J. van Wijnen, Mark E. Morrey, Joaquin Sanchez-Sotelo, Daniel J. Berry, Jodi M. Carter, Matthew P. Abdel
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Arthrofibrosis following total knee arthroplasty (TKA) is a debilitating condition typically diagnosed based on clinical findings. To gain insight into the histopathologic immune cell microenvironment of arthrofibrosis, we assessed the exten
Externí odkaz:
https://doaj.org/article/1c40645896924d1bb2bff3c1f5b012f5
Autor:
Harold I. Salmons, Christopher Gow, Afton K. Limberg, Jacob W. Bettencourt, Mason F. Carstens, Ashley N. Payne, Mark E. Morrey, Joaquin Sanchez-Sotelo, Daniel J. Berry, Amel Dudakovic, Matthew P. Abdel
Publikováno v:
Tissue Engineering Part C: Methods. 29:154-159
Autor:
Amel Dudakovic, Banu Bayram, Jacob W. Bettencourt, Afton K. Limberg, M. Lizeth Galvan, Margarita E. Carrasco, Britta Stans, Roman Thaler, Mark E. Morrey, Joaquin Sanchez‐Sotelo, Daniel J. Berry, Andre J. van Wijnen, Matthew P. Abdel
Publikováno v:
Journal of Cellular Biochemistry. 124:320-334
Autor:
Banu Bayram, Roman Thaler, Jacob W. Bettencourt, Afton K. Limberg, Kevin P. Sheehan, Aaron R. Owen, Daniel J. Berry, Mark E. Morrey, Joaquin Sanchez‐Sotelo, Andre J. Wijnen, Amel Dudakovic, Matthew P. Abdel
Publikováno v:
Journal of Cellular Biochemistry, 123(5), 878-892. Wiley-Liss Inc.
J Cell Biochem
J Cell Biochem
Arthrofibrosis is characterized by excessive extracellular matrix (ECM) deposition that results in restricted joint motion after total knee arthroplasties (TKAs). Currently, treatment options are limited. Therefore, an in vitro model of knee-related
Autor:
Jacob W, Bettencourt, Cody C, Wyles, Douglas R, Osmon, Arlen D, Hanssen, Daniel J, Berry, Matthew P, Abdel
Publikováno v:
The Bone & Joint Journal. :227-234
Aims Septic arthritis of the hip often leads to irreversible osteoarthritis (OA) and the requirement for total hip arthroplasty (THA). The aim of this study was to report the mid-term risk of any infection, periprosthetic joint infection (PJI), asept
Autor:
Banu Bayram, Aaron R. Owen, Amel Dudakovic, Louis Dagneaux, Travis W. Turner, Jacob W. Bettencourt, Afton K. Limberg, Meagan E. Tibbo, Mark E. Morrey, Joaquin Sanchez-Sotelo, Daniel J. Berry, Jean-Pierre A. Kocher, Andre J. van Wijnen, Matthew P. Abdel
Publikováno v:
Journal of Clinical Medicine, Vol 9, Iss 11, p 3690 (2020)
(1) Background: Arthrofibrosis is a common cause of patient debility and dissatisfaction after total knee arthroplasty (TKA). The diversity of molecular pathways involved in arthrofibrosis disease progression suggest that effective treatments for art
Externí odkaz:
https://doaj.org/article/90d1fb01becc4f92b155e5f892cc6a2b
Autor:
Jacob W. Bettencourt, Peter C. Amadio, Jonathan D. Barlow, Aaron R. Owen, Mark E. Morrey, Jean Pierre A. Kocher, Joaquin Sanchez-Sotelo, Andre J. van Wijnen, Louis Dagneaux, Daniel J. Berry, Matthew P. Abdel
Publikováno v:
J Arthroplasty
Background Pathologic fibrosis is characterized by dysregulation of gene expression with excessive extracellular matrix production. The genetic basis for solid organ fibrosis is well described in the literature. However, there is a paucity of evidenc
Autor:
Zhaolan Hu, Tuantuan V. Zhao, Tao Huang, Shozo Ohtsuki, Ke Jin, Isabel N. Goronzy, Bowen Wu, Matthew P. Abdel, Jacob W. Bettencourt, Gerald J. Berry, Jörg J. Goronzy, Cornelia M. Weyand
Publikováno v:
Nat Metab
Tissue macrophages (Mϕ) are essential effector cells in rheumatoid arthritis (RA), contributing to autoimmune tissue inflammation through diverse effector functions. Their arthritogenic potential depends on their proficiency to survive in the glucos
Autor:
Afton K. Limberg, Christopher G. Salib, Andre J. van Wijnen, Eric A. Lewallen, Banu Bayram, Matthew P. Abdel, Daniel J. Berry, William H. Trousdale, Joaquin Sanchez-Sotelo, Mark E. Morrey, Jacob W. Bettencourt, Roman Thaler, Christopher R. Paradise, Nicolas Reina
Publikováno v:
Genomics
Arthrofibrosis is an abnormal histopathologic response, is debilitating for patients, and poses a substantial unsolved clinical challenge. This study characterizes molecular biomarkers and regulatory pathways associated with arthrofibrosis by compari