Zobrazeno 1 - 10
of 312
pro vyhledávání: '"Jacob Tfelt‐Hansen"'
Autor:
Mie Rath Refn, Mikkel Meyer Andersen, Marie-Louise Kampmann, Jacob Tfelt-Hansen, Erik Sørensen, Margit Hørup Larsen, Niels Morling, Claus Børsting, Vania Pereira
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract DNA methylation, a pivotal epigenetic modification, plays a crucial role in regulating gene expression and is known to undergo dynamic changes with age. The present study investigated epigenome-wide methylation profiles in 64 individuals ove
Externí odkaz:
https://doaj.org/article/143c3d298673469aa0adeb44daf008e8
Autor:
Mikkel Eriksen Dupont, Stine Bøttcher Jacobsen, Steffan Noe Niikanoff Christiansen, Jacob Tfelt-Hansen, Morten Holdgaard Smerup, Jeppe Dyrberg Andersen, Niels Morling
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Untreated fresh cardiac tissue is the optimal tissue material for investigating DNA methylation patterns of cardiac biology and diseases. However, fresh tissue is difficult to obtain. Therefore, tissue stored as frozen or formalin-fixed, par
Externí odkaz:
https://doaj.org/article/8e82ee68189f4169ad2396f415d01eb0
Autor:
Nunu Laura Timotheussen Lund, Anja Sofie Petersen, Rolf Fronczek, Jacob Tfelt-Hansen, Andrea Carmine Belin, Tore Meisingset, Erling Tronvik, Anna Steinberg, Charly Gaul, Rigmor Højland Jensen
Publikováno v:
The Journal of Headache and Pain, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Aim Treatment for cluster headache is currently based on a trial-and-error approach. The available preventive treatment is unspecific and based on few and small studies not adhering to modern standards. Therefore, the authors collaborated to
Externí odkaz:
https://doaj.org/article/6cc9183bf3c34d3f9e1200835e3d2942
Autor:
Paulina Pruszkowska-Przybylska, Mikkel Eriksen Dupont, Stine Bøttcher Jacobsen, Morten Smerup, Jacob Tfelt-Hansen, Niels Morling, Jeppe Dyrberg Andersen
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0299557 (2024)
The continued development in methylome analysis has enabled a more precise assessment of DNA methylation, but treatment of target tissue prior to analysis may affect DNA analysis. Prediction of age based on methylation levels in the genome (DNAmAge)
Externí odkaz:
https://doaj.org/article/6cf5d5cdb18e411c97a71a06bb6e02ca
Autor:
Mikkel E. Dupont, Steffan N. Christiansen, Stine B. Jacobsen, Marie-Louise Kampmann, Kristine B. Olsen, Jacob Tfelt-Hansen, Jytte Banner, Niels Morling, Jeppe D. Andersen
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Archived formalin-fixed and paraffin-embedded (FFPE) heart tissue from autopsied individuals represents an important resource for investigating the DNA methylation of heart tissue of deceased individuals. The DNA quality of FFPE tissue from
Externí odkaz:
https://doaj.org/article/5b83f3aed0224b26aa7f0179883e2bc8
Autor:
Steffan Noe Christiansen, Jeppe Dyrberg Andersen, Marie-Louise Kampmann, Jing Liu, Mikkel Meyer Andersen, Jacob Tfelt-Hansen, Niels Morling
Publikováno v:
Epigenetics, Vol 17, Iss 12, Pp 1636-1645 (2022)
The Infinium MethylationEPIC BeadChip (EPIC) is a reliable method for measuring the DNA methylation of more than 850,000 CpG positions. In clinical and forensic settings, it is critical to be able to work with low DNA amounts without risking reduced
Externí odkaz:
https://doaj.org/article/924f15373a08427dbd28fa99f965e87b
Autor:
Arthur A. M. Wilde, Christopher Semsarian, Manlio F. Márquez, Alireza Sepehri Shamloo, Michael J. Ackerman, Euan A. Ashley, Back Sternick Eduardo, Héctor Barajas‐Martinez, Elijah R. Behr, Connie R. Bezzina, Jeroen Breckpot, Philippe Charron, Priya Chockalingam, Lia Crotti, Michael H. Gollob, Steven Lubitz, Naomasa Makita, Seiko Ohno, Martín Ortiz‐Genga, Luciana Sacilotto, Eric Schulze‐Bahr, Wataru Shimizu, Nona Sotoodehnia, Rafik Tadros, James S. Ware, David S. Winlaw, Elizabeth S. Kaufman, Takeshi Aiba, Andreas Bollmann, Jong‐Il Choi, Aarti Dalal, Francisco Darrieux, John Giudicessi, Mariana Guerchicoff, Kui Hong, Andrew D. Krahn, Ciorsti Mac Intyre, Judith A. Mackall, Lluís Mont, Carlo Napolitano, Pablo Ochoa Juan, Petr Peichl, Alexandre C. Pereira, Peter J. Schwartz, Jon Skinner, Christoph Stellbrink, Jacob Tfelt‐Hansen, Thomas Deneke
Publikováno v:
Journal of Arrhythmia, Vol 38, Iss 4, Pp 491-553 (2022)
Externí odkaz:
https://doaj.org/article/065b869d10df4d35a27b0f57e20fcc2b
Autor:
Camilla H. B. Jespersen, Johanna Krøll, Priya Bhardwaj, Carl Johann Hansen, Jesper Svane, Bo G. Winkel, Christian Jøns, Peter Karl Jacobsen, Jens Haarbo, Jens Cosedis Nielsen, Jens Brock Johansen, Berit T. Philbert, Sam Riahi, Christian Torp‐Pedersen, Lars Køber, Jacob Tfelt‐Hansen, Peter E. Weeke
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 7 (2023)
Background Patients with Brugada syndrome (BrS) are recommended to avoid drugs that may increase their risk of arrhythmic events. We examined treatment with such drugs in patients with BrS after their diagnosis. Methods and Results All Danish patient
Externí odkaz:
https://doaj.org/article/f0aa4ea3d9cc40a5b070cda0eb5ee8be
Autor:
Julie Terp Holm, Niels Kjær Stampe, Priya Bhardwaj, Reza Jabbari, Finn Gustafsson, Niels Risum, Jacob Tfelt-Hansen, Bo Gregers Winkel
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 45, Iss , Pp 101188- (2023)
Aims: Cardiac arrest (CA) survivors with left/right bundle branch block (LBBB/RBBB) and no ischemic heart disease (IHD) have not been previously characterized. The aim of this study was to describe heart failure, implantable cardioverter defibrillato
Externí odkaz:
https://doaj.org/article/c1a12d81c28c49948c87e6ee7d828ec6
Autor:
Stine Bøttcher Jacobsen, Jacob Tfelt-Hansen, Morten Holdgaard Smerup, Jeppe Dyrberg Andersen, Niels Morling
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0283159 (2023)
The use of fresh tissue for molecular studies is preferred but often impossible. Instead, frozen or formalin-fixed, paraffin-embedded (FFPE) tissues are widely used and constitute valuable resources for retrospective studies. We assessed the utility
Externí odkaz:
https://doaj.org/article/a305a047e0904639aefa532a2e2fdc39