Zobrazeno 1 - 10 of 23 pro vyhledávání: '"Jacob T. Minang"'
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Influenza Antigens NP and M2 Confer Cross Protection to BALB/c Mice against Lethal Challenge with H1N1, Pandemic H1N1 or H5N1 Influenza A Viruses
Autor: Thomas E Hickey, Sonja Leyrer, Hanné Andersen, Nathan D. Grubaugh, Nutan Mytle, Jon R Inglefield, Andrea M. Harris, Michael J. Lacy, Hang Lu, Tina Guina, Jacob T. Minang, Mario H. Skiadopoulos, Zhidong Ma
Publikováno v: Viruses
Volume 13
Issue 9
Viruses, Vol 13, Iss 1708, p 1708 (2021)
Influenza hemagglutinin (HA) is considered a major protective antigen of seasonal influenza vaccine but antigenic drift of HA necessitates annual immunizations using new circulating HA versions. Low variation found within conserved non-HA influenza v
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f6dd00762e01096e14f5c801c2ec946
http://europepmc.org/articles/PMC8473317
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3
Akademický článek
Transduction of SIV-specific TCR genes into rhesus macaque CD8+ T cells conveys the ability to suppress SIV replication.
Autor: Eugene V Barsov, Matthew T Trivett, Jacob T Minang, Haosi Sun, Claes Ohlen, David E Ott
Publikováno v: PLoS ONE, Vol 6, Iss 8, p e23703 (2011)
The SIV/rhesus macaque model for HIV/AIDS is a powerful system for examining the contribution of T cells in the control of AIDS viruses. To better our understanding of CD8(+) T-cell control of SIV replication in CD4(+) T cells, we asked whether TCRs
Externí odkaz: https://doaj.org/article/4a1cc3fc6c7d41ebb2e59eaaa0004694
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4
Correction: Transduction of SIV-Specific TCR Genes into Rhesus Macaque CD8+ T Cells Conveys the Ability to Suppress SIV Replication
Autor: David E. Ott, Claes Ohlen, Jacob T. Minang, Matthew T. Trivett, Haosi Sun, Eugene V. Barsov
Publikováno v: PLoS ONE
PLoS ONE, Vol 13, Iss 3, p e0195246 (2018)
The SIV/rhesus macaque model for HIV/AIDS is a powerful system for examining the contribution of T cells in the control of AIDS viruses. To better our understanding of CD8(+) T-cell control of SIV replication in CD4(+) T cells, we asked whether TCRs
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7f5c91709629ab768e57922fac940c3
http://europepmc.org/articles/PMC5874069
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5
TCR triggering transcriptionally downregulates CCR5 expression on rhesus macaque CD4+ T-cells with no measurable effect on susceptibility to SIV infection
Autor: David E. Ott, Eugene V. Barsov, Gregory Q. Del Prete, Jacob T. Minang, Claes Ohlen, Michael Piatak, James A. Thomas, Matthew T. Trivett, Charles M. Trubey, Robert J. Gorelick
Publikováno v: Virology. 409(1):132-140
Studies using transformed human cell lines suggest that most SIV strains use CCR5 as co-receptor. Our analysis of primary rhesus macaque CD4 + T-cell clones revealed marked differences in susceptibility to SIV mac 239 infection. We investigated wheth
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e696fdd883a7667272ae2018b96a709
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6
Trafficking, Persistence, and Activation State of Adoptively Transferred Allogeneic and Autologous Simian Immunodeficiency Virus-Specific CD8+ T Cell Clones during Acute and Chronic Infection of Rhesus Macaques
Autor: Michael Piatak, Jeffrey D. Lifson, Diane L. Bolton, Yuan Li, Matthew T. Trivett, Mario Roederer, Jennifer J. Tuscher, David H. O’Connor, Claes Ohlen, Kaimei Song, Jacob T. Minang
Publikováno v: The Journal of Immunology. 184:303-314
Despite multiple lines of evidence suggesting their involvement, the precise role of CD8+ T cells in controlling HIV replication remains unclear. To determine whether CD8+ T cells can limit retroviral replication in the absence of other immune respon
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::994a70c64e680c24369b4d8031497a47
https://doi.org/10.4049/jimmunol.0902413
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Nef-mediated MHC class I down-regulation unmasks clonal differences in virus suppression by SIV-specific CD8+ T cells independent of IFN-γ and CD107a responses
Autor: Michael Piatak, Lori V. Coren, Matthew T. Trivett, Jacob T. Minang, Eugene V. Barsov, Claes Ohlen, David E. Ott
Publikováno v: Virology. 391(1):130-139
CD8 + T lymphocytes (CTL) play a role in controlling HIV/SIV infection. CTL antiviral activity is dependent on recognition of antigenic peptides associated with MHC class I molecules on infected target cells, and CTL activation can be impaired by Nef
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79fb9479a8dcda95348a012086e89f7f
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8
Is the variability of nickel patch test reactivity over time associated with fluctuations in the systemic T-cell reactivity to nickel?
Autor: Magnus Bruze, Khosro Masjedi, Niklas Ahlborg, Jacob T. Minang, Monica Hindsén
Publikováno v: British Journal of Dermatology. 161:102-109
Background Patch test reactivity to nickel varies over time. To what extent this variation is associated with fluctuations in the T-cell reactivity to nickel is not known. Objectives Our aim was to investigate the relationship between variation over
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6ec9ffd682b9bd3fcc987c2fa42e50b
https://doi.org/10.1111/j.1365-2133.2009.09182.x
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Efficient inhibition of SIV replication in rhesus CD4+ T-cell clones by autologous immortalized SIV-specific CD8+ T-cell clones
Autor: Michael Piatak, David E. Ott, Jacob T. Minang, Claes Ohlen, Fang Yuan, Matthew T. Trivett, Eugene V. Barsov, Jeffrey D. Lifson
Publikováno v: Virology. 372:430-441
CD8(+) cytotoxic T lymphocyte (CTL) responses play an important role in controlling the replication of primate lentiviruses. Induction of these responses is a key objective for most current AIDS vaccine approaches. Despite a variety of approaches for
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09fab2abba2b98b56838254f1d70f330
https://doi.org/10.1016/j.virol.2007.11.013
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