Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jacob Sweezey-Munroe"'
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
IntroductionAberrant cleavage of the transmembrane protein, amyloid-beta precursor protein (ABPP), results in the overproduction of amyloid-beta (AB) peptides which can form senile plaques in the brain. These plaques can get lodged within synapses an
Externí odkaz:
https://doaj.org/article/af43d2e9c1c04d71b2c797992f345062
Autor:
Bianca M. Marcella, Mia S. Geromella, Ahmad Mohammad, Jacob Sweezey-Munroe, Rebecca E. K. MacPherson, Val A. Fajardo
Publikováno v:
Muscles. 1:152-161
The sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA) actively transports Ca2+ into the sarcoplasmic reticulum to facilitate cardiac muscle relaxation. Phospholamban (PLN) allosterically inhibits SERCA, and an imbalance of SERCA2a, dominant cardiac is