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Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 80:1095-1109
Acute Promyelocytic Leukemia (APL) results from a reciprocal translocation that fuses the gene for the PML tumor suppressor to that encoding the retinoic acid receptor alpha (RARα). The resulting PML-RARα oncogene product interferes with multiple r