Zobrazeno 1 - 10
of 336
pro vyhledávání: '"Jacob Schaefer"'
Autor:
Hao Yang, Daryl Staveness, Steven M. Ryckbosch, Alison D. Axtman, Brian A. Loy, Alexander B. Barnes, Vijay S. Pande, Jacob Schaefer, Paul A. Wender, Lynette Cegelski
Publikováno v:
ACS Central Science, Vol 4, Iss 1, Pp 89-96 (2018)
Bryostatin 1 (henceforth bryostatin) is in clinical trials for the treatment of Alzheimer’s disease and for HIV/AIDS eradication. It is also a preclinical lead for cancer immunotherapy and other therapeutic indications. Yet nothing is known about t
Externí odkaz:
https://doaj.org/article/0c4021d3b7b3445188b8df92455c1628
Publikováno v:
ZooKeys, Vol 227, Iss 0, Pp 49-62 (2012)
A new species of Profundulus, P. kreiseri (Cyprinodontiformes: Profundulidae), is described from the Chamelecón and Ulúa Rivers in the northwestern Honduran highlands. Based on a phylogenetic analysis using cytochrome b and the presence of synapomo
Externí odkaz:
https://doaj.org/article/7b277d8156464351a8f7ef4811399b00
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0118742 (2015)
Assessing the impacts of the Deepwater Horizon oil spill with a dependable baseline comparison can provide reliable insight into environmental stressors on organisms that were potentially affected by the spill. Fluctuating asymmetry (small, non-rando
Externí odkaz:
https://doaj.org/article/625c4acf28cc41c6936da3347bd13f0e
Publikováno v:
Abstracts of the 27th Annual Meeting of the GCMAS.
Publikováno v:
The Journal of chemical physics. 157(4)
Recent progress in establishing local order in polycarbonate-like glasses using rotational echo double resonance and centerband-only detection of exchange solid-state nuclear magnetic resonance (NMR) has stimulated a renewed attempt to connect molecu
Sex differences in brain tumor glutamine metabolism reveal sex-specific vulnerabilities to treatment
Autor:
Jasmin Sponagel, Jill K. Jones, Cheryl Frankfater, Shanshan Zhang, Olivia Tung, Kevin Cho, Kelsey L. Tinkum, Hannah Gass, Elena Nunez, Douglas R. Spitz, Prakash Chinnaiyan, Jacob Schaefer, Gary J. Patti, Maya S. Graham, Audrey Mauguen, Milan Grkovski, Mark P. Dunphy, Simone Krebs, Jingqin Luo, Joshua B. Rubin, Joseph E. Ippolito
Publikováno v:
Med (New York, N.Y.). 3(11)
Brain cancer incidence and mortality rates are greater in males. Understanding the molecular mechanisms that underlie those sex differences could improve treatment strategies. Although sex differences in normal metabolism are well described, it is cu
Sex Differences in Brain Tumor Glutamine Metabolism Reveal Sex-Specific Vulnerabilities to Treatment
Autor:
Prakash Chinnaiyan, Jacob Schaefer, Kevin Cho, Jones Jk, Tung O, Cheryl Frankfater, Tinkum Kl, Nunez E, Audrey Mauguen, Josh Rubin, Jasmin Sponagel, Joseph E. Ippolito, Sisi Zhang, Krebs S, Maya S. Graham, Milan Grkovski, Gary J. Patti, Douglas R. Spitz, Jingqin Luo, Mark Dunphy, Gass H
SummarySex differences in normal metabolism are well described, but whether they persist in cancerous tissue is unknown. We assessed metabolite abundance in glioblastoma surgical specimens and found that male glioblastomas are enriched for amino acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40185f9b62367f06751a2c314053d3d1
https://doi.org/10.1101/2021.09.29.461531
https://doi.org/10.1101/2021.09.29.461531
Autor:
Jacob Schaefer
Publikováno v:
ACS Symposium Series ISBN: 9780841237100
ACS Symposium Series
ACS Symposium Series
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7a42e2d2c2e373a667327576d497c44
https://doi.org/10.1021/bk-2020-1349.ch005
https://doi.org/10.1021/bk-2020-1349.ch005
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1860:749-756
Staphylococcus aureus biofilms pose a serious clinical threat as reservoirs for persistent infections. Despite this clinical significance, the composition and mechanism of formation of S. aureus biofilms are unknown. To address these problems, we use
Autor:
Vijay S. Pande, Brian Loy, Paul A. Wender, Alison D. Axtman, Alexander B. Barnes, Jacob Schaefer, Steven M. Ryckbosch, Lynette Cegelski, Daryl Staveness, Hao Yang
Publikováno v:
ACS Central Science
ACS Central Science, Vol 4, Iss 1, Pp 89-96 (2018)
ACS Central Science, Vol 4, Iss 1, Pp 89-96 (2018)
Bryostatin 1 (henceforth bryostatin) is in clinical trials for the treatment of Alzheimer’s disease and for HIV/AIDS eradication. It is also a preclinical lead for cancer immunotherapy and other therapeutic indications. Yet nothing is known about t