Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Jacob S. Heng"'
Publikováno v:
International Journal of Retina and Vitreous, Vol 8, Iss 1, Pp 1-9 (2022)
Abstract Background The purpose of this study was to evaluate visual acuity after cataract surgery in eyes with Macular Telangiectasia (MacTel) Type 2. Methods Single-center retrospective cohort study of patients with MacTel Type 2 who underwent cata
Externí odkaz:
https://doaj.org/article/5d4bb30dd6cb466da63f90336cdb52a6
Publikováno v:
American Journal of Ophthalmology Case Reports, Vol 27, Iss , Pp 101607- (2022)
Purpose: To describe a case of local recurrence of uveal melanoma with concomitant brain metastases after secondary enucleation. Observations: A 73 year-old patient presented with dizziness and gait instability. MRI of the orbits and brain showed an
Externí odkaz:
https://doaj.org/article/bcf5286f66fa4c17a688ec54e79449e8
Autor:
Karl J. Wahlin, Jie Cheng, Shawna L. Jurlina, Melissa K. Jones, Nicholas R. Dash, Anna Ogata, Nawal Kibria, Sunayan Ray, Kiara C. Eldred, Catherine Kim, Jacob S. Heng, Jenny Phillips, Robert J. Johnston, David M. Gamm, Cynthia Berlinicke, Donald J. Zack
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Human pluripotent stem cells (PSCs) represent a powerful tool to investigate human eye development and disease. When grown in 3D, they can self-assemble into laminar organized retinas; however, variation in the size, shape and composition of individu
Externí odkaz:
https://doaj.org/article/9163c7a815ae44529b224062f12f13fe
Publikováno v:
Case Reports in Surgery, Vol 2015 (2015)
Filiform polyposis represents a rare but recognised manifestation on the varied spectrum of histopathology in colonic tuberculosis. We report a case of filiform polyposis secondary to colonic tuberculosis presenting as colo-colonic intussusception di
Externí odkaz:
https://doaj.org/article/8380b7d9b79b452bb2ac9f9e1203e3d0
Autor:
Rahul M. Dhodapkar, Jane Z. Spadaro, Jacob S. Heng, John H. Sinard, Yan Ho Lee, Larissa A. Habib, Renelle Pointdujour-Lim
Publikováno v:
Ophthalmic Plastic & Reconstructive Surgery.
Autor:
Jacob S Heng, Loyal A. Goff, Sean F. Hackett, Genevieve Stein-O’Brien, Briana L. Winer, John Williams, Jeremy Nathans
Publikováno v:
Proc Natl Acad Sci U S A
Autoimmune uveoretinitis is a significant cause of visual loss, and mouse models offer unique opportunities to study its disease mechanisms. Aire −/− mice fail to express self-antigens in the thymus, exhibit reduced central tolerance, and develop
Autor:
Loyal A. Goff, Jacob S Heng, Jeremy Nathans, Briana L. Winer, Amir Rattner, Hilary J. Vernon, Bryan W. Jones, Genevieve Stein-O’Brien
Publikováno v:
Proceedings of the National Academy of Sciences. 116:9103-9114
The mammalian CNS is capable of tolerating chronic hypoxia, but cell type-specific responses to this stress have not been systematically characterized. In the Norrin KO ( Ndp KO ) mouse, a model of familial exudative vitreoretinopathy (FEVR), develop
Autor:
Jacob S Heng, Jenna M Kim, D Kyle Jones, Kathleen M Stoessel, Sarah A Weiss, Mario Sznol, Harriet M Kluger, Scott D Walter, Niki A Silverstein, Renelle Pointdujour-Lim
Publikováno v:
BMJ Open Ophthalmology
ObjectiveTo demonstrate the spectrum of autoimmune retinopathy (AIR) associated with immunotherapy for advanced cutaneous melanoma.Methods and analysisRetrospective chart review on patients with advanced cutaneous melanoma who developed AIR after ini
Autor:
Alastair Lockwood, Jacob S Heng, Peng T. Khaw, Sahar Awwad, Steve Brocchini, Garima Sharma, Abeer Mohamed Ahmed
Publikováno v:
British Journal of Pharmacology. 174:4205-4223
The eye is a highly specialised organ that is subject to a huge range of pathology. Both local and systemic disease may affect different anatomical regions of the eye. The least invasive routes for ocular drug administration are topical (e.g. eyedrop
Autor:
Chongyuan Luo, Rosa Castanon, Amir Rattner, Joseph R. Nery, Jacob S Heng, Loyal A. Goff, Mark F Sabbagh, Jeremy Nathans, Joseph R. Ecker
Publikováno v:
eLife
eLife, Vol 7 (2018)
eLife, Vol 7 (2018)
Vascular endothelial cell (EC) function depends on appropriate organ-specific molecular and cellular specializations. To explore genomic mechanisms that control this specialization, we have analyzed and compared the transcriptome, accessible chromati