Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jacob R. Thorstensen"'
Autor:
Jacob R. Thorstensen
Publikováno v:
The Journal of Physiology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7eea073a74e5db4d6ee42a9ec2decdb3
https://doi.org/10.1113/jp284738
https://doi.org/10.1113/jp284738
Serotonin modulates corticospinal excitability, motoneurone firing rates and contractile strength via 5-HT2receptors. However, the effects of these receptors on cortical and motoneurone excitability during voluntary contractions have not been explore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa323d7bfe2d4ee8bb5259cd1d06c0f6
https://doi.org/10.1101/2023.04.26.538484
https://doi.org/10.1101/2023.04.26.538484
Autor:
Justin J. Kavanagh, Steven Morrison, Tyler Thomas Henderson, Murray G. Tucker, Jacob R Thorstensen
Publikováno v:
Journal of Neurophysiology. 127:27-37
Although there is evidence that 5-HT acts as an excitatory neuromodulator to enhance maximal force generation, it is largely unknown how 5-HT activity influences the ability to sustain a constant force during steady-state contractions. A total of 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07710a5cf6ddbdb4f0f4ebcb7e0f2972
https://doi.org/10.1152/jn.00403.2021
https://doi.org/10.1152/jn.00403.2021
Autor:
Tyler T. Henderson, Janet L. Taylor, Jacob R. Thorstensen, Murray G. Tucker, Justin J. Kavanagh
Publikováno v:
Journal of neurophysiology. 128(4)
Serotonin (5-HT) modulates motoneuron excitability during muscle contractions, where the release of 5-HT in the central nervous system (CNS) is linked to the intensity of physical activity. Although there is evidence that enhanced availability of 5-H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d8c2dd57abeebce539aa4937fe7a8a1
https://pubmed.ncbi.nlm.nih.gov/36001790
https://pubmed.ncbi.nlm.nih.gov/36001790
Publikováno v:
The Journal of Physiology. 598:2685-2701
KEY POINTS: During maximal effort contractions, intense serotonin release via the raphe-spinal pathway spills over from the somato-dendritic compartment to activate inhibitory 5-HT1A receptors on the axon initial segment of motoneurons to reduce moto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccd0cfeb19e7bbe07d11efc0ac0eebdc
https://doi.org/10.1113/jp279347
https://doi.org/10.1113/jp279347
Publikováno v:
The European journal of neuroscience. 56(1)
The intrinsic electrical properties of motoneurons strongly affect motoneuron excitability to fast-acting excitatory ionotropic inputs. Serotonin (5-HT) is a neurochemical that alters the intrinsic properties of motoneurons, whereby animal models and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c9b5ece27d09b93d46c880f0e91c68a2
https://pubmed.ncbi.nlm.nih.gov/35445439
https://pubmed.ncbi.nlm.nih.gov/35445439
Publikováno v:
Journal of neurophysiology. 125(4)
Animal models indicate that serotonin (5-HT) release onto motoneurons facilitates motor output, particularly during strong motor activities. However, evidence for 5-HT effects during human movement are limited. This study examined how antagonism of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::42bc151601747ff0be6cc2efc2e80c3b
https://pubmed.ncbi.nlm.nih.gov/33596722
https://pubmed.ncbi.nlm.nih.gov/33596722
Publikováno v:
Neuropharmacology. 141:343-352
Neural circuits that comprise the indirect pathway in the basal ganglia have been implicated in tremor genesis, and possibly play a role in the voluntary activation of muscles. However, an absence of in vivo human studies that target striatal D2 dopa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e31cec301f2a5897370a6e4260f494a8
https://doi.org/10.1016/j.neuropharm.2018.08.029
https://doi.org/10.1016/j.neuropharm.2018.08.029
Publikováno v:
Neuropharmacology. 141
Neural circuits that comprise the indirect pathway in the basal ganglia have been implicated in tremor genesis, and possibly play a role in the voluntary activation of muscles. However, an absence of in vivo human studies that target striatal D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2488dad9bfd4ce3dab86f0cc9412f940
https://pubmed.ncbi.nlm.nih.gov/30171987
https://pubmed.ncbi.nlm.nih.gov/30171987