Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jacob R. Becraft"'
Autor:
Séan Mc Cafferty, Darrell J. Irvine, Tasuku Kitada, Jacob R. Becraft, Niek N. Sanders, Ron Weiss, Francis Combes, Mathias Devreese, Joyca De Temmerman, Siegrid De Baere
Publikováno v:
Mol Ther
Synthetic mRNA therapeutics have the potential to revolutionize healthcare, as they enable patients to produce therapeutic proteins inside their own bodies. However, convenient methods that allow external control over the timing and magnitude of prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25edd2a77eaf2a9d20e68ce58f9533aa
https://doi.org/10.1016/j.ymthe.2020.11.010
https://doi.org/10.1016/j.ymthe.2020.11.010
Autor:
Niek N. Sanders, Katie Bodner, Tyler E Wagner, Oliwia Andries, Brian Dobosh, Tasuku Kitada, Jacob R. Becraft, Jacob Beal, Xin Zhang, Amanda Woo, Douglas Densmore, Ron Weiss, Bremy Alburquerque, Porter Ely Blanton, Brian Teague
Publikováno v:
Nature Chemical Biology. 14:1043-1050
Synthetic mRNA is an attractive vehicle for gene therapies because of its transient nature and improved safety profile over DNA. However, unlike DNA, broadly applicable methods to control expression from mRNA are lacking. Here we describe a platform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a7442dfe8e39c3fab2f7d15212be01
https://doi.org/10.1038/s41589-018-0146-9
https://doi.org/10.1038/s41589-018-0146-9
Publikováno v:
Biomaterials Science. 3:645-654
The design of biomaterials for increasingly complex tissue engineering applications often requires exogenous presentation of biomolecular signals. Integration of gene delivery vectors with a biomaterial scaffold offers the potential to bypass the use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b66ee2c6bf3695b5346a7fd1a6e8db69
https://doi.org/10.1039/c5bm00033e
https://doi.org/10.1039/c5bm00033e
Autor:
Aneta J. Mieszawska, Max L. Senders, Erik S.G. Stroes, May Tun Saung, Robert Langer, Omid C. Farokhzad, Mark E. Lobatto, Brenda L. Sanchez-Gaytan, YongTae Kim, Zahi A. Fayad, Jacob R. Becraft, Ronald E. Gordon, Mingming Ma, Tomohiro Kawahara, Willem J. M. Mulder, Francois Fay, Bomy Lee Chung, Claudia Calcagno
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 111(3), 1078-1083. National Academy of Sciences
Therapeutic and diagnostic nanomaterials are being intensely studied for several diseases, including cancer and atherosclerosis. However, the exact mechanism by which nanomedicines accumulate at targeted sites remains a topic of investigation, especi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c703e9c752787fdecfc52c822e9cd6dc
https://doi.org/10.1073/pnas.1322725111
https://doi.org/10.1073/pnas.1322725111
Autor:
Willem J. M. Mulder, Robert Langer, Nazila Kamaly, Jacob R. Becraft, Zahi A. Fayad, Yoshitaka J. Sei, Bomy Lee Chung, Omid C. Farokhzad, YongTae Kim, Michael J. Toth
Publikováno v:
Technical University of Denmark Orbit
PMC
PMC
The endothelium lines the internal surfaces of blood and lymphatic vessels and has a critical role in maintaining homeostasis. Endothelial dysfunction is involved in the pathology of many diseases and conditions, including disorders such as diabetes,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be3310458ba75ddf364c2d0cf038b8f4
https://orbit.dtu.dk/en/publications/267639ac-9a10-4e26-b29b-b7cbbeb22efb
https://orbit.dtu.dk/en/publications/267639ac-9a10-4e26-b29b-b7cbbeb22efb
