Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jacob R Hambrook"'
Autor:
Jacob R Hambrook, Patrick C Hanington
Publikováno v:
PLoS Pathogens, Vol 19, Iss 2, p e1010884 (2023)
Schistosoma mansoni employs immune evasion and immunosuppression to overcome immune responses mounted by its snail and human hosts. Myriad immunomodulating factors underlie this process, some of which are proteases. Here, we demonstrate that one prot
Externí odkaz:
https://doaj.org/article/0f7ebe0e18704441b2191d52064132f2
Autor:
Hongyu Li, Jacob R Hambrook, Emmanuel A Pila, Abdullah A Gharamah, Jing Fang, Xinzhong Wu, Patrick Hanington
Publikováno v:
eLife, Vol 9 (2020)
Immune factors in snails of the genus Biomphalaria are critical for combating Schistosoma mansoni, the predominant cause of human intestinal schistosomiasis. Independently, many of these factors play an important role in, but do not fully define, the
Externí odkaz:
https://doaj.org/article/00a4eae5c1894e14a020443c0d608ba3
Publikováno v:
PLoS Pathogens, Vol 14, Iss 10, p e1007393 (2018)
Metalloproteases (MPs) have demonstrated roles in immune modulation. In some cases, these enzymes are produced by parasites to influence host immune responses such that parasite infection is facilitated. One of the best examples of parasite-mediated
Externí odkaz:
https://doaj.org/article/3af11594e63c4eedaf11dec7b5006a59
Publikováno v:
Immunogenetics. 74:77-98
The immune cells of the snail Biomphalaria glabrata are classified into hyalinocyte and granulocyte subtypes. Both subtypes are essential for the proper functioning of the snail immune response, which we understand best within the context of how it r
Schistosoma mansoniemploys immune evasion and immunosuppression to overcome immune responses mounted by its snail and human hosts. Myriad immunomodulating factors underlie this process, some of which are proteases. Here, we demonstrate that one prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68c8b4372f2b33a4291e87e1c482d171
https://doi.org/10.1101/2022.09.16.508213
https://doi.org/10.1101/2022.09.16.508213
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Frontiers in Immunology
Frontiers in Immunology
Human schistosomes combat the unique immune systems of two vastly different hosts during their indirect life cycles. In gastropod molluscs, they face a potent innate immune response composed of variable immune recognition molecules and highly phagocy
Autor:
Emmanuel A. Pila, Abdullah A Gharamah, Jacob R. Hambrook, Patrick C. Hanington, Solomon Hussein
Publikováno v:
Genes, Vol 11, Iss 1, p 38 (2019)
Genes
Volume 11
Issue 1
Genes
Volume 11
Issue 1
Gastropod molluscs, which have co-evolved with parasitic digenean trematodes for millions of years, utilize circulating heamocytes as the primary method of containing and killing these invading parasites. In order to do so, they must generate suitabl
Autor:
Jacob R. Hambrook, Hongyu Li, Patrick C. Hanington, Emmanuel A. Pila, Xinzhong Wu, Abdullah A Gharamah, Jing Fang
Publikováno v:
eLife, Vol 9 (2020)
Immune factors in snails of the genusBiomphalariaare critical for combatingSchistosoma mansoni, the predominant cause of human intestinal schistosomiasis. Independently, many of these factors are known to play an important role in, but not fully defi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c112b38b6f5fac84b621cd191dda790c
https://doi.org/10.1101/767699
https://doi.org/10.1101/767699
Autor:
Hongyu, Li, Jacob R, Hambrook, Emmanuel A, Pila, Abdullah A, Gharamah, Jing, Fang, Xinzhong, Wu, Patrick, Hanington
Publikováno v:
eLife
Immune factors in snails of the genus Biomphalaria are critical for combating Schistosoma mansoni, the predominant cause of human intestinal schistosomiasis. Independently, many of these factors play an important role in, but do not fully define, the