Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jacob P. Harney"'
Autor:
Jacob P. Harney, Kathryn Gudsnuk, Ami Patel, Anantha R. Vellipuram, Sathyajit Bandaru, David Butler
Publikováno v:
Ketogenic Diet and Metabolic Therapies ISBN: 0190497998
This chapter reviews endocrine, behavioral, and reproductive outcomes of the ketogenic diet (KD) in rodent mouse and rat models. KD treatment can result in conditions seen in metabolic syndrome, including dyslipidemia and inflammation. Females raised
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::691f28d669dd4106eed9effff0f65bc1
https://doi.org/10.1093/med/9780190497996.003.0025
https://doi.org/10.1093/med/9780190497996.003.0025
Publikováno v:
Journal of molecular neuroscience : MN. 60(1)
For decades, the ketogenic diet has been an effective treatment of intractable epilepsy in children. Childhood epilepsy is pharmacoresistant in 25–40 % of patients taking the current prescribed medications. Chronic seizure activity has been linked
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03d2006c2401460e64b17429d9024bec
https://pubmed.ncbi.nlm.nih.gov/27320113
https://pubmed.ncbi.nlm.nih.gov/27320113
Publikováno v:
Physiology & Behavior. 100:239-244
Alterations in two components of the brain's insulin signaling pathway, docosahexaenoic acid (DHA) content and phosphoinositide 3-kinase (PI3K) activity, have been implicated in the insulin resistance that is central to type II diabetes mellitus (DM)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff8d89a150cda1c3574808dac73bfaa2
https://doi.org/10.1016/j.physbeh.2009.10.019
https://doi.org/10.1016/j.physbeh.2009.10.019
Publikováno v:
Neuropsychopharmacology. 32:522-530
Intrinsic rewarding effects of estradiol (E(2)) may underlie some of the sex differences that emerge postpuberty for the prevalence of drug use and behavioral responses to drugs, but the effects and mechanisms of E(2) for reward have not been well ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3af4df527d79a325d7a18b87a2d29315
https://doi.org/10.1038/sj.npp.1301124
https://doi.org/10.1038/sj.npp.1301124
Publikováno v:
Brain Research. 1000:8-18
Of the many people that have epilepsy, only about 70% achieve seizure control with traditional pharmacotherapies. Steroids have long been known to influence ictal activity and may have a therapeutic role. This review summarizes recent investigations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d11a73f5ce6b466788305511a9128576
https://doi.org/10.1016/j.brainres.2003.12.023
https://doi.org/10.1016/j.brainres.2003.12.023
Publikováno v:
Brain Research. 948:165-170
Testosterone's (T) aggression-enhancing effects may be mediated in part by its 5alpha-reduced, 3-hydroxysteroid dehydrogenized metabolite 5alpha-androstane-3alpha,17beta-diol (3alpha-diol). To test this hypothesis, in Expt. 1 gonadectomized (gdx) C21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6c8f31c776e68993bc5f7fc9be9d21
https://doi.org/10.1016/s0006-8993(02)03076-7
https://doi.org/10.1016/s0006-8993(02)03076-7
Publikováno v:
Epilepsia. 43:14-17
Summary: Purpose: To investigate the importance of progesterone (P4) metabolism by the 5α-reductase type I enzyme in mitigating P4 antiseizure effects. Methods: Ovariectomized, female homozygous and heterozygous 5α-reductase type I knockout mice (n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::045d254cd45f31b1659edf616f7658ae
https://doi.org/10.1046/j.1528-1157.43.s.5.19.x
https://doi.org/10.1046/j.1528-1157.43.s.5.19.x
Publikováno v:
Epilepsy Research. 49:239-246
The present study was designed to evaluate the effects of acute inhibition of fatty acid oxidation on plasma levels of beta hydroxybutyrate and latency to PTZ-induced seizures in ad libitum- (AL), calorie-restricted normal rodent chow- (CR), and calo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48910f0aa71cf58646a0e2d78d2691b7
https://doi.org/10.1016/s0920-1211(02)00046-3
https://doi.org/10.1016/s0920-1211(02)00046-3
Publikováno v:
Journal of Reproductive Immunology. 31:185-198
Interleukin-1 beta (IL-1 beta) is one of the critical inflammatory cytokines involved in many physiological processes. This study investigated the temporal expression of IL-1 beta in pig conceptuses. A human IL-1 beta cDNA probe and a anti-human IL-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11189bc6351f38f7cda3d96c4a6aeb2a
https://doi.org/10.1016/0165-0378(96)00975-8
https://doi.org/10.1016/0165-0378(96)00975-8
Publikováno v:
Biology of Reproduction. 53:133-142
Colony-stimulating factor-1 (CSF-1), a growth factor for cells of monocyte/macrophage lineages, is produced by uterine and placental tissues in humans and mice and may stimulate placental growth and development. The present study characterized CSF-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16c6249fa302fad3f1fba2cf4612b9f5
https://doi.org/10.1095/biolreprod53.1.133
https://doi.org/10.1095/biolreprod53.1.133