Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jacob Noeker"'
Autor:
Ki-Sun Park, Beenish Rahat, Hyung Chul Lee, Zu-Xi Yu, Jacob Noeker, Apratim Mitra, Connor M Kean, Russell H Knutsen, Danielle Springer, Claudia M Gebert, Beth A Kozel, Karl Pfeifer
Publikováno v:
eLife, Vol 10 (2021)
Maternal loss of imprinting (LOI) at the H19/IGF2 locus results in biallelic IGF2 and reduced H19 expression and is associated with Beckwith–-Wiedemann syndrome (BWS). We use mouse models for LOI to understand the relative importance of Igf2 and H1
Externí odkaz:
https://doaj.org/article/9585b4d7825b4eb19926c26cb2be1f3c
Decreasing Wapl dosage partially corrects transcriptome phenotypes in Nipbl-/+ embryonic mouse brain
Autor:
Connor M. Kean, Christopher J. Tracy, Apratim Mitra, Matthew T Van Winkle, Claudia M Gebert, Jacob Noeker, Anne L. Calof, Arthur D. Lander, Judith A. Kassis, Karl Pfeifer
Cohesin rings interact with DNA and modulate expression of thousands of genes. NIPBL loads cohesin onto chromosomes and WAPL takes it off. Heterozygous mutations in NIPBL lead to a developmental disorder called Cornelia de Lange syndrome. Nipbl heter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7be961b450c7721577653b98e3e10c09
https://doi.org/10.1101/2022.05.31.493745
https://doi.org/10.1101/2022.05.31.493745
Autor:
Danielle A. Springer, Claudia Gebert, Zu-Xi Yu, Beenish Rahat, Karl Pfeifer, Connor M Kean, Russell H Knutsen, Ki-Sun Park, Hyung Chul Lee, Apratim Mitra, Beth A. Kozel, Jacob Noeker
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Maternal loss of imprinting (LOI) at the H19/IGF2 locus results in biallelic IGF2 and reduced H19 expression and is associated with Beckwith–-Wiedemann syndrome (BWS). We use mouse models for LOI to understand the relative importance of Igf2 and H1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::424f807a4c02e8ae3e49f294705470da
https://doi.org/10.7554/elife.67250
https://doi.org/10.7554/elife.67250
Autor:
Jacob Noeker, Zu-Xi Yu, Danielle A. Springer, Ki-Sun Park, Hyung Chul Lee, Karl Pfeifer, Russell H. Knutsen, Claudia Gebert, Apratim Mitra, Beth A. Kozel, Connor M Kean, Beenish Rahat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::057fc984f9700e84d1336c6fb5bbd8dd
https://doi.org/10.7554/elife.67250.sa2
https://doi.org/10.7554/elife.67250.sa2
Autor:
Beth A. Kozel, Ki-Sun Park, Danielle A. Springer, Beenish Rahat, Russell H Knutsen, Jacob Noeker, Apratim Mitra, Zu-Xi Yu, Karl Pfeifer
Maternal loss of imprinting (LOI) at the H19/IGF2 locus results in biallelic IGF2 and reduced H19 expression and is associated with Beckwith Wiedemann syndrome (BWS). We use mouse models for LOI to understand the relative importance of Igf2 and H19 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e16b8f1e2e33a11191297f453ad2f531
https://doi.org/10.1101/2021.02.23.432554
https://doi.org/10.1101/2021.02.23.432554