Extracellular superoxide dismutase regulates cardiac function and fibrosis

Autor: Kenneth R. McGaffin, Jacob M. Tobolewski, Xiaodong Zhu, Hagir B. Suliman, Charles F. McTiernan, Brian J. Day, Claude A. Piantadosi, Crystal M. Reynolds, Tim D. Oury, Corrine R. Kliment

Publikováno v: Journal of Molecular and Cellular Cardiology. 47:730-742

Extracellular superoxide dismutase (EC-SOD) is an antioxidant that protects the heart from ischemia and the lung from inflammation and fibrosis. The role of cardiac EC-SOD under normal conditions and injury remains unclear. Cardiac toxicity, a common

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d91a8b3d3371af6b6844b506540d5b2d
https://doi.org/10.1016/j.yjmcc.2009.08.010

Lack of the receptor for advanced glycation end-products attenuates E. coli pneumonia in mice

Autor: Lasse Ramsgaard, Ruben Zamora, Lauren T. Crum, Michelle L. Manni, Jacob M. Tobolewski, Judson M. Englert, Tim D. Oury, Yoram Vodovotz, Gina M. Coudriet, Jon D. Piganelli, Jan J. Enghild, Julia V. Gefter, Pavle S. Milutinovic

Publikováno v: Ramsgaard, L, Englert, J M, Manni, M L, Milutinovic, P S, Gefter, J, Tobolewski, J, Crum, L, Coudriet, G M, Piganelli, J, Zamora, R, Vodovotz, Y, Enghild, J J & Oury, T D 2011, ' Lack of the receptor for advanced glycation end-products attenuates E. coli pneumonia in mice ', P L o S One, vol. 6, no. 5, pp. e20132 . https://doi.org/10.1371/journal.pone.0020132
PLoS ONE
PLoS ONE, Vol 6, Iss 5, p e20132 (2011)

Background: The receptor for advanced glycation end-products (RAGE) has been suggested to modulate lung injury in models of acute pulmonary inflammation. To study this further, model systems utilizing wild type and RAGE knockout (KO) mice were used t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a10439464d32cb2538fbc55c93e722d2
https://pure.au.dk/portal/da/publications/lack-of-the-receptor-for-advanced-glycation-endproducts-attenuates-e-coli-pneumonia-in-mice(19571437-e155-46cc-b697-43145a6569c6).html

Gender-specific Responses To Experimental Silica-induced Lung Fibrosis

Autor: Jacob M. Tobolewski, Cheryl L. Fattman, Sarah M. Reilly, David M. Brass, Mary K. Dunkel

Publikováno v: A58. ANIMAL MODELS OF PULMONARY FIBROSIS.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0c3b20c7bbc727f6e7dcfb8a20b1e9aa
https://doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a1990

The role of the receptor for advanced glycation end-products in a murine model of silicosis

Autor: Jacob M. Tobolewski, Adriana S. Leme, Jan J. Enghild, A. Murat Kaynar, Tim D. Oury, Steven D. Shapiro, Cheryl L. Fattman, Lauren Tomai, Judson M. Englert, Lasse Ramsgaard

Publikováno v: Ramsgaard, L, Englert, J M, Tobolewski, J, Tomai, L, Fattman, C L, Leme, A S, Kaynar, A M, Shapiro, S D, Enghild, J J & Oury, T D 2010, ' The role of the receptor for advanced glycation end-products in a murine model of silicosis ', P L o S One, vol. 5, no. 3, pp. e9604 . https://doi.org/10.1371/journal.pone.0009604
PLoS ONE, Vol 5, Iss 3, p e9604 (2010)
PLoS ONE

Udgivelsesdato: 2010-null BACKGROUND: The role of the receptor for advanced glycation end-products (RAGE) has been shown to differ in two different mouse models of asbestos and bleomycin induced pulmonary fibrosis. RAGE knockout (KO) mice get worse f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3a3e6133381e568b34a39840b7e08c5
https://pure.au.dk/ws/files/48531540/journal.pone.0009604.pdf

Extracellular Matrix Powder Attenuates Bleomycin-Induced Pulmonary Fibrosis

Autor: Thomas W. Gilbert, Tim D. Oury, Jacob M. Tobolewski, Michelle L. Manni

Publikováno v: A59. STEM CELL AND TISSUE ENGINEERING THERAPEUTICS.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8ced23d7516a9c740e1af581e2b6bf30
https://doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a2015