Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jacob M. Smigiel"'
Endogenous OSM expression and recombinant OSM does not alter cell growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f8ced7094be847c37f90bd17b07670e
https://doi.org/10.1158/1541-7786.22516428.v1
https://doi.org/10.1158/1541-7786.22516428.v1
Pancreatic ductal adenocarcinoma (PDAC) is referred to as a silent killer due to the lack of clear symptoms, a lack of early detection methods, and a high frequency of metastasis at diagnosis. In addition, pancreatic cancer is remarkably resistant to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76d52c16f6489933686521c59adcb555
https://doi.org/10.1158/1541-7786.c.6541362
https://doi.org/10.1158/1541-7786.c.6541362
Schematic of FACS to isolate CD24HI/CD44LOW and CD24LOW/CD44HI cells from parental HPAC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68aa45bd6166259508450fb4b68b12ae
https://doi.org/10.1158/1541-7786.22516437.v1
https://doi.org/10.1158/1541-7786.22516437.v1
OSM induces expression of the CSC marker CD133
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03df3ce1346759642b7a8221ee158faf
https://doi.org/10.1158/1541-7786.22516431
https://doi.org/10.1158/1541-7786.22516431
Sorted CD24HI/CD44LOW populations retain phenotype in culture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::361a429284ac91cbca2d6a8ff8660627
https://doi.org/10.1158/1541-7786.22516434
https://doi.org/10.1158/1541-7786.22516434
Normal tissue expression of OSM, OSMR, JAK and STAT3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40918e933b3b11383e35dc010810529a
https://doi.org/10.1158/1541-7786.22516419.v1
https://doi.org/10.1158/1541-7786.22516419.v1
OSM promotes migration on multiple matrices
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d92a760a32aae5f0a06110ba9aed26b
https://doi.org/10.1158/1541-7786.22516425
https://doi.org/10.1158/1541-7786.22516425
OSM promotes tumorigenicity even at limiting cell numbers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75ee6a8ed704350e9efda7270e2349cb
https://doi.org/10.1158/1541-7786.22516422
https://doi.org/10.1158/1541-7786.22516422
OSM & OSMR mRNA levels in pancreatic cancer and normal tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::057857e1ac0b818920ce0dcffdb2bb4d
https://doi.org/10.1158/1541-7786.22516440
https://doi.org/10.1158/1541-7786.22516440
Autor:
Wilnelly Hernandez-Sanchez, Mark W. Jackson, Courtney A. Bartel, Neetha Parameswaran, Jacob M. Smigiel, Ahmad M. Khalil, Kristy Miskimen
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports
Scientific Reports
Pancreatic ductal adenocarcinomas (PDAC) are deadly on account of the delay in diagnosis and dearth of effective treatment options for advanced disease. The insurmountable hurdle of targeting oncogene KRAS, the most prevalent genetic mutation in PDAC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee6f3ac94448a0267f4b71cc00f27c8
http://link.springer.com/article/10.1038/s41598-019-49475-5
http://link.springer.com/article/10.1038/s41598-019-49475-5
