Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jacob M. Miszuk"'
Publikováno v:
Molecular pharmaceutics. 19(12)
FDA-approved bone morphogenetic protein 2 (BMP2) has serious side effects due to the super high dose requirement. Heparin is one of the most well-studied sulfated polymers to stabilize BMP2 and improve its functionality. However, the clinical use of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::294a9abe5071e62e6a7d6442196a8caf
https://pubmed.ncbi.nlm.nih.gov/35675584
https://pubmed.ncbi.nlm.nih.gov/35675584
Publikováno v:
ACS Appl Bio Mater
Complex shaped and critical-sized bone defects have been a clinical challenge for many years. Scaffold-based strategies such as hydrogels provide localized drug release while filling complex defect shapes, but ultimately possess weaknesses in low mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b780f2a26378f6e1cb3564b7797552b
https://doi.org/10.1021/acsabm.1c00134
https://doi.org/10.1021/acsabm.1c00134
Publikováno v:
ACS Appl Bio Mater
Repair of large bone defects using biomaterials-based strategies has been a significant challenge due to the complex characteristics required for tissue regeneration, especially in the craniofacial region. Tissue engineering strategies aimed at resto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbe45df581c7d8b3784f1d6daf8fe88d
https://doi.org/10.1021/acsabm.0c00946
https://doi.org/10.1021/acsabm.0c00946
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. 108:2699-2710
Three-dimensional (3D) scaffolds with interconnected, hierarchically structured pores, and biomimetic nanostructures are desirable for tissue engineering, where preparation with a facile and biocompatible strategy remains challenging. In the present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1d2c0d9aca344481e68c8ccf93caeee
https://doi.org/10.1002/jbm.b.34601
https://doi.org/10.1002/jbm.b.34601
Autor:
Zhuozhi Wang, Jue Hu, Jeffrey A. Banas, Jacob M. Miszuk, Alexei V. Tivanski, Hongli Sun, Min Zhu, Thiranjeewa I. Lansakara
Publikováno v:
Carbohydr Polym
Chitosan scaffolds crosslinked by current methods insufficiently meet the demands of bone tissue engineering applications. We developed a novel effective crosslinking technique by using the natural and safe vanillin together with bioglass micropartic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c43342280a5b864defe0d3f736dc9076
https://pubmed.ncbi.nlm.nih.gov/34364578
https://pubmed.ncbi.nlm.nih.gov/34364578
Autor:
Bassam M. Abunahel, Komal Agarwal, S. Anandhan, Rafaela S. Andre, Ukrit Angkawinitwong, Ying Bai, Avinash Baji, Michael Max Brown, Arief Budiman, Bowen Cheng, Amutha Chinnappan, Daniel S. Correa, Rangika De Silva, Yu Dong, Ela Eroglu, Murilo H.M. Facure, Hao Fong, Olga Gavrilenko, Aleksandra Gavrilovic-Wohlmuther, Gibin George, Kheng-Lim Goh, Raju Kumar Gupta, Liumin He, Nesar Hossain, Israt Jahan, W.A.D.M. Jayathilaka, Weimin Kang, Erich Kny, Jinsong Leng, Zongjie Li, Zhipeng Liang, Loong-Tak Lim, Tong Lin, Dongyan Liu, Yanju Liu, Yong Liu, Xia Lou, Zhiping Luo, Luiza A. Mercante, Jacob M. Miszuk, Soheila Mohammadzadehmoghadam, Haitao Niu, Nurul Zahirah Noor Azman, Akiko Obata, Pooria Pasbakhsh, Adriana Pavinatto, Gowsihan Poologasundarampillai, Daping Quan, Arifur Rahman, Seeram Ramakrishna, Rahul Sahay, T. Senthil, Narendra Singh, Guoxin Sui, Hongli Sun, Youhong Tang, Ioana Carmen Vladu, Linlin Wang, Min Wang, Xin Wang, Gareth R. Williams, Xiang-Fa Wu, Yuliang Xia, Tao Xu, Qingqing Yao, Fenghua Zhang, Oksana Zholobko, Hua Zhou, Yu Zhou, Zhengping Zhou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c19494290794c6c21ae32572c5d7561
https://doi.org/10.1016/b978-0-12-819611-3.09990-8
https://doi.org/10.1016/b978-0-12-819611-3.09990-8
The development of highly biomimetic nanofibrous scaffolds that possess a morphological structure similar to the natural extracellular matrix is a major technological challenge in tissue engineering. Electrospun nanofibers have been demonstrated as p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5be81fcecc6dcf57d1cd3418c54f20c
https://doi.org/10.1016/b978-0-12-819611-3.00006-6
https://doi.org/10.1016/b978-0-12-819611-3.00006-6
Publikováno v:
Appl Mater Today
Nanoclay (Nanosilicates, NS) is appearing as an intriguing 2D nanomaterial for bone tissue engineering with multiple proposed functions, e.g., intrinsic osteoinductivity, improving mechanical properties, and drug release capacity. However, the mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0143f53720406b7ac7e7277869ef2805
https://pubmed.ncbi.nlm.nih.gov/33225042
https://pubmed.ncbi.nlm.nih.gov/33225042
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 171:31-39
Three-dimensional (3D) scaffolds as artificial ECMs have been extensively studied to mimic the critical features of natural ECMs. To develop more clinically relevant 3D scaffolds, electrospun nanofibrous scaffolds with different weight ratios of PCL/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::078e2dc5f891d81e55beab62f4db7905
https://doi.org/10.1016/j.colsurfb.2018.07.004
https://doi.org/10.1016/j.colsurfb.2018.07.004
Autor:
Paulo H. S. Picciani, Jaqueline G. L. Cosme, Jacob M. Miszuk, Qingqing Yao, Tao Xu, Hao Fong, Hongli Sun
Publikováno v:
Biomaterials. 115:115-127
Nanofibrous scaffolds that are morphologically/structurally similar to natural ECM are highly interested for tissue engineering; however, the electrospinning technique has the difficulty in directly producing clinically relevant 3D nanofibrous scaffo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c2da1bebaab81953d3a95c3daf4a111
https://doi.org/10.1016/j.biomaterials.2016.11.018
https://doi.org/10.1016/j.biomaterials.2016.11.018