Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jacob M. Majikes"'
Autor:
Seulki Cho, Alexander Zaslavsky, Curt A. Richter, Jacob M. Majikes, J. Alexander Liddle, François Andrieu, Sylvain Barraud, Arvind Balijepalli
Publikováno v:
2022 International Electron Devices Meeting (IEDM).
Autor:
Samuel P. Forry, Paul N. Patrone, J. Alexander Liddle, Daniel Schiffels, Jacob M. Majikes, Anthony J. Kearsley, Michael Zwolak
Publikováno v:
Nucleic Acids Res
Structural DNA nanotechnology, as exemplified by DNA origami, has enabled the design and construction of molecularly-precise objects for a myriad of applications. However, limitations in imaging, and other characterization approaches, make a quantita
Publikováno v:
Biophys J
Biomolecular thermodynamics, particularly for DNA, are frequently determined via van’t Hoff analysis of optically measured melt curves. Accurate and precise values of thermodynamic parameters are essential for the modeling of complex systems involv
Autor:
J. Alexander Liddle, Jacob M. Majikes
Publikováno v:
Novel Patterning Technologies 2021.
Nucleic acid self-assembly is a nanofabrication technology that exists at the intersection between conventional silicon fabrication, enzymes, small molecule synthesis, and polymer manufacturing. While it cannot compete directly with any one of these
Publikováno v:
ACS nano. 15(2)
Understanding the folding process of DNA origami is a critical stepping stone to the broader implementation of nucleic acid nanofabrication technology but is notably nontrivial. Origami are formed by several hundred cooperative hybridization events-f
Autor:
Jacob M. Majikes, J. Alexander Liddle
Publikováno v:
Journal of Research of the National Institute of Standards and Technology. 126
While the design and assembly of DNA origami are straightforward, its relative novelty as a nanofabrication technique means that the tools and methods for designing new structures have not been codified as well as they have for more mature technologi
Publikováno v:
New Journal of Physics, Vol 18, Iss 11, p 115001 (2016)
Scaffolded DNA origami are a robust tool for building discrete nanoscale objects at high yield. This strategy ensures, in the design process, that the desired nanostructure is the minimum free energy state for the designed set of DNA sequences. Despi
Externí odkaz:
https://doaj.org/article/0f1bb9022b15473589e8d690fc2cb203
Publikováno v:
Novel Patterning Technologies for Semiconductors, MEMS/NEMS and MOEMS 2020.
Publikováno v:
Anal Biochem
Fluorescence-based measurements are a standard tool for characterizing the thermodynamic properties of DNA systems. Nonetheless, experimental melt data obtained from polymerase chain-reaction (PCR) machines (for example) often leads to signals that v
Autor:
Shuai Zhang, Rui Campos, Jacob M. Majikes, Elena E. Ferapontova, Lucas C. C. Ferraz, Thomas H. LaBean, Mingdong Dong
Publikováno v:
de Almeida Campos, R C, Zhang, S, Majikes, J M, Ferraz, L C C, LaBean, T H, Dong, M D & Ferapontova, E E 2015, ' Electronically addressable nanomechanical switching of i-motif DNA origami assembled on basal plane HOPG ', Chemical Communications, vol. 51, no. 74, pp. 14111-14114 . https://doi.org/10.1039/c5cc04678e
Here, a pH-induced nanomechanical switching of i-motif structures incorporated into DNA origami bound onto cysteamine-modified basal plane HOPG was electronically addressed, demonstrating for the first time the electrochemical read-out of the nanomec