Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Jacob M. Kaufman"'
Autor:
David P. Carbone, Joseph M. Amann, Cynthia D. Timmers, Kyungho Park, Tadaaki Yamada, Jacob M. Kaufman
LKB1 is a commonly mutated tumor suppressor in non–small cell lung cancer that exerts complex effects on signal transduction and transcriptional regulation. To better understand the downstream impact of loss of functional LKB1, we developed a trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2f699616c0aad34b539ebd484056c11
https://doi.org/10.1158/0008-5472.c.6508526.v1
https://doi.org/10.1158/0008-5472.c.6508526.v1
Autor:
David P. Carbone, Christopher Oakes, Vicki H. Wysocki, Mark B. Gerstein, Rajeswara Rao Arasada, Nicole Cacciato, Joseph M. Amann, Fabio C.P. Navarro, Christoph Weigel, Walter Z. Wang, Michael F. Sharpnack, Jacob M. Kaufman, Bernice A. Agana, Michael J. Koenig
Figures S1-S13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01751544b6604c25f26444dff25e47b3
https://doi.org/10.1158/0008-5472.22428778
https://doi.org/10.1158/0008-5472.22428778
Autor:
David P. Carbone, Christopher Oakes, Vicki H. Wysocki, Mark B. Gerstein, Rajeswara Rao Arasada, Nicole Cacciato, Joseph M. Amann, Fabio C.P. Navarro, Christoph Weigel, Walter Z. Wang, Michael F. Sharpnack, Jacob M. Kaufman, Bernice A. Agana, Michael J. Koenig
Supplementary Data Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb2305f24ef6afa602a99f2d5e8bd910
https://doi.org/10.1158/0008-5472.22428775.v1
https://doi.org/10.1158/0008-5472.22428775.v1
Autor:
David P. Carbone, Joseph M. Amann, Cynthia D. Timmers, Kyungho Park, Tadaaki Yamada, Jacob M. Kaufman
Supporting information including gene correlation matrix for LKB1 loss signature genes and additional drug sensitivity analyses.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48f8aebd91069ff28dd200f1d101d521
https://doi.org/10.1158/0008-5472.22412822.v1
https://doi.org/10.1158/0008-5472.22412822.v1
Autor:
David P. Carbone, Christopher Oakes, Vicki H. Wysocki, Mark B. Gerstein, Rajeswara Rao Arasada, Nicole Cacciato, Joseph M. Amann, Fabio C.P. Navarro, Christoph Weigel, Walter Z. Wang, Michael F. Sharpnack, Jacob M. Kaufman, Bernice A. Agana, Michael J. Koenig
STK11 (liver kinase B1, LKB1) is the fourth most frequently mutated gene in lung adenocarcinoma, with loss of function observed in up to 30% of all cases. Our previous work identified a 16-gene signature for LKB1 loss of function through mutational a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56bb95b4dfb8b8f4c36c982e1ea1f139
https://doi.org/10.1158/0008-5472.c.6513136.v1
https://doi.org/10.1158/0008-5472.c.6513136.v1
Autor:
David P. Carbone, Joseph M. Amann, Cynthia D. Timmers, Kyungho Park, Tadaaki Yamada, Jacob M. Kaufman
Reported LKB1 mutations in cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d80c38f96a2adea96156d58b6d94365
https://doi.org/10.1158/0008-5472.22412813
https://doi.org/10.1158/0008-5472.22412813
Autor:
David P. Carbone, Joseph M. Amann, Cynthia D. Timmers, Kyungho Park, Tadaaki Yamada, Jacob M. Kaufman
Regression associations between LKB1 loss signature and inhibitors in GDSC, CTRP, and CCLE studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d953e21de81df5e279e60feea3013f5
https://doi.org/10.1158/0008-5472.22412810
https://doi.org/10.1158/0008-5472.22412810
Autor:
David P. Carbone, Joseph M. Amann, Cynthia D. Timmers, Kyungho Park, Tadaaki Yamada, Jacob M. Kaufman
Gene expression data for resected lung adenocarcinomas and cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c6203610ab91f0f5ffa680510f67caf
https://doi.org/10.1158/0008-5472.22412807.v1
https://doi.org/10.1158/0008-5472.22412807.v1
Autor:
David P. Carbone, Joseph M. Amann, Cynthia D. Timmers, Kyungho Park, Tadaaki Yamada, Jacob M. Kaufman
Mutational information for cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b66dab7c3a995fa594e2f31e003fdf0
https://doi.org/10.1158/0008-5472.22412816.v1
https://doi.org/10.1158/0008-5472.22412816.v1
Autor:
Walter Wang, Bernice A. Agana, Rajeswara Rao Arasada, Fabio C. P. Navarro, Christoph Weigel, Vicki H. Wysocki, David P. Carbone, Christopher C. Oakes, Joseph M. Amann, Mark Gerstein, Nicole Cacciato, Michael J. Koenig, Michael F. Sharpnack, Jacob M. Kaufman
Publikováno v:
Cancer Research. 81:4194-4204
STK11 (liver kinase B1, LKB1) is the fourth most frequently mutated gene in lung adenocarcinoma, with loss of function observed in up to 30% of all cases. Our previous work identified a 16-gene signature for LKB1 loss of function through mutational a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8679700d2a1d7cce78bc8fce48d63bb9
https://doi.org/10.1158/0008-5472.can-20-3199
https://doi.org/10.1158/0008-5472.can-20-3199
