Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jacob M. Hornby"'
Publikováno v:
BMC Complementary and Alternative Medicine, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background With the current concern caused by drug resistant microorganisms, alternatives to traditional antimicrobials are increasingly necessary. Historical holistic treatments involving natural approaches are now of interest as a potentia
Externí odkaz:
https://doaj.org/article/6a344f41e23b4f46b06bc103a247b4b3
Publikováno v:
BMC Complementary and Alternative Medicine, Vol 19, Iss 1, Pp 1-9 (2019)
BMC Complementary and Alternative Medicine
BMC Complementary and Alternative Medicine
Background With the current concern caused by drug resistant microorganisms, alternatives to traditional antimicrobials are increasingly necessary. Historical holistic treatments involving natural approaches are now of interest as a potential alterna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af9c7e558497978e373754759528fbc5
http://link.springer.com/article/10.1186/s12906-019-2666-6
http://link.springer.com/article/10.1186/s12906-019-2666-6
Publikováno v:
Applied and Environmental Microbiology. 72:3805-3813
Production of farnesol by Candida albicans is the first quorum-sensing system discovered in a eukaryote ([29][1]). In C. albicans , accumulated farnesol affects both dimorphism ([29][1], [50][2]) and biofilm formation ([62][3]). Fungal dimorphism is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::485c824ced80d7e69750bfae0d581f9e
https://doi.org/10.1128/aem.02765-05
https://doi.org/10.1128/aem.02765-05
Publikováno v:
Molecular Microbiology. 59:753-764
The dimorphic fungus Candida albicans secretes farnesol, which acts as a quorum-sensing molecule and prevents the yeast to mycelium conversion. In this study we examined the effect of farnesol in the filamentous fungus Aspergillus nidulans. We show t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40da7ebbc80365af8aa171b4fc99610c
https://doi.org/10.1111/j.1365-2958.2005.04976.x
https://doi.org/10.1111/j.1365-2958.2005.04976.x
Autor:
Jacob M. Hornby, Natasha Hoerrmann, Dhammika H. M. L. P. Navarathna, Gerald E. Duhamel, Kenneth W. Nickerson, Anne M. Parkhurst
Publikováno v:
Journal of Antimicrobial Chemotherapy. 56:1156-1159
OBJECTIVES To investigate the relative pathogenicity of Candida albicans treated with subinhibitory concentrations of fluconazole in a mouse model of disseminated candidiasis. Previous studies indicate that these cells secrete 10 times more farnesol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16f2dfae3b5e7175bc6067a5c938f297
https://doi.org/10.1093/jac/dki383
https://doi.org/10.1093/jac/dki383
Publikováno v:
Antimicrobial Agents and Chemotherapy. 48:2350-2354
The polymorphic fungus Candida albicans is one of the most versatile opportunistic pathogens in humans. Many organs of the human body are potential targets for infection by this pathogen, but infection is commonly localized in the gastrointestinal tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d286e2e43ec2afd65e84a7aebe162a8
https://doi.org/10.1128/aac.48.7.2350-2354.2004
https://doi.org/10.1128/aac.48.7.2350-2354.2004
Publikováno v:
Journal of Microbiological Methods. 56:119-124
A method is described for the formation of nearly 100% pseudohyphae populations of wild-type Candida albicans A72. The method employs fungal growth at 37 degrees C (ca. 5x10(6) cells/ml) in a glucose-proline-N-acetyl-glucosamine medium supplemented w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17285f1fa6115d1c99b69abf6311c965
https://doi.org/10.1016/j.mimet.2003.09.021
https://doi.org/10.1016/j.mimet.2003.09.021
Autor:
Erin Burger, Timothy Niessen, Jacob M. Hornby, Patrick H. Dussault, Roman V. Shchepin, Kenneth W. Nickerson
Publikováno v:
Chemistry & Biology. 10(8):743-750
The dimorphic fungus Candida albicans produces extracellular farnesol (3,7,11-trimethyl-2,6,10-dodecatriene-1-ol) which acts as a quorum-sensing molecule (QSM) to suppress filamentation. Of four possible geometric isomers of farnesol, only the E,E is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53da03ee078b0b9abfe1eb4d2d495ddc
Publikováno v:
Antimicrobial Agents and Chemotherapy. 47:2366-2369
The dimorphic fungus Candida albicans produces farnesol as a quorum-sensing molecule that regulates cellular morphology. The biosynthetic origin of farnesol has been resolved by treating these cells with zaragozic acid B, a potent inhibitor of squale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77eeec21561827ec478386d9ff47bdf5
https://doi.org/10.1128/aac.47.7.2366-2369.2003
https://doi.org/10.1128/aac.47.7.2366-2369.2003
Autor:
Dhammika H. M. L. P. Navarathna, Navasona Krishnan, Anne M. Parkhurst, Gerald E. Duhamel, Kenneth W. Nickerson, Jacob M. Hornby
Publikováno v:
Infection and immunity. 75(4)
This work extends our previous observation that the fungus Candida albicans secretes micromolar levels of farnesol and that accumulation of farnesol in vitro prevents the yeast-to-mycelium conversion in a quorum-sensing manner. What does farnesol do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e89e49a4ba1bdbca3c4c122799863f89
https://pubmed.ncbi.nlm.nih.gov/17283095
https://pubmed.ncbi.nlm.nih.gov/17283095