Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jacob M. Carlson"'
Autor:
Liberty François-Moutal, David Donald Scott, Andrew J. Ambrose, Christopher J. Zerio, Marina Rodriguez-Sanchez, Kumara Dissanayake, Danielle G. May, Jacob M. Carlson, Edward Barbieri, Aubin Moutal, Kyle J. Roux, James Shorter, Rajesh Khanna, Sami J. Barmada, Leeanne McGurk, May Khanna
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with no cure or effective treatment in which TAR DNA Binding Protein of 43 kDa (TDP-43) abnormally accumulates into misfolded protein aggregates in affected neurons. It
Externí odkaz:
https://doaj.org/article/15ebfd3809d6429cb150916d1d91bb88
Autor:
Mohan Pal, Lei Miao, Andrej Perdih, Jacob M. Carlson, Nurul H. Ansari, Yuting Yang, Zaneta Nikolovska-Coleska, Jennifer L. Meagher, Jeanne A. Stuckey, Chenzhong Liao, Karson J. Kump, Ahmed S.A. Mady, Fardokht A. Abulwerdi, May Khanna, Uttar K. Shrestha, Krishnapriya Chinnaswamy
Publikováno v:
J Med Chem
Anti-apoptotic Bcl-2 family proteins are overexpressed in a wide spectrum of cancers and have become well validated therapeutic targets. Cancer cells display survival dependence on individual or subsets of anti-apoptotic proteins that could be effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2062c9229794d2b22c7358918295967
https://doi.org/10.1021/acs.jmedchem.9b01442
https://doi.org/10.1021/acs.jmedchem.9b01442
Autor:
Liberty François-Moutal, David Donald Scott, Andrew J. Ambrose, Christopher J. Zerio, Marina Rodriguez-Sanchez, Kumara Dissanayake, Danielle G. May, Jacob M. Carlson, Edward Barbieri, Aubin Moutal, Kyle J. Roux, James Shorter, Rajesh Khanna, Sami J. Barmada, Leeanne McGurk, May Khanna
Publikováno v:
Scientific reports. 12(1)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with no cure or effective treatment in which TAR DNA Binding Protein of 43 kDa (TDP-43) abnormally accumulates into misfolded protein aggregates in affected neurons. It is widel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9204dbad44d9d7a47634a8c3a208605
https://pubmed.ncbi.nlm.nih.gov/35581326
https://pubmed.ncbi.nlm.nih.gov/35581326
Autor:
Ritin Sharma, Jacob M. Carlson, Vinodh Narayanan, Patrick Pirrotte, Kristin Leskoke, Judith A. Tello, Seema Plaisier, Melissa N. Martinez, Matthew J. Huentelman, Liberty François-Moutal, Francesca Vitali, Keri Ramsey, Ben Stansfield, Sampath Rangasamy, May Khanna, Patrick Pirotte, Llorida Llaci, Roberta Diaz Brinton, Jared M. Churko, Krystine Garcia-Mansfield
Publikováno v:
SSRN Electronic Journal.
Pontocerebellar Hypoplasia 1B (PCH1B) patients exhibit profound underdevelopment of the neocerebellum and its adjacent structures, leading to severe developmental delays as well as poor survival. Here, we report a new case of PCH1B with a known mutat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3df5c1f1bb5b469ed99b8af8765e8c43
https://doi.org/10.2139/ssrn.3744495
https://doi.org/10.2139/ssrn.3744495
Autor:
Lei Miao, Fardokht A. Abulwerdi, May Khanna, Yuting Yang, Jennifer L. Meagher, Jacob M. Carlson, Mohan Pal, Karson J. Kump, Andrej Perdih, Zaneta Nikolovska-Coleska, Nurul H. Ansari, Ahmed A. Mady, Uttar K. Shrestha, Krishnapriya Chinnaswamy, Jeanne A. Stuckey, Chenzhong Liao
Publikováno v:
Cancer Research. 80:LB-226
Anti-apoptotic Bcl-2 family proteins are frequently overexpressed in various cancers and are established therapeutic targets. Cancer cells can either display dependence on individual or subsets of these pro-survival proteins, which gives therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa95d5093c2125db60eb966b4fc32540
https://doi.org/10.1158/1538-7445.am2020-lb-226
https://doi.org/10.1158/1538-7445.am2020-lb-226