Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Jacob M Kowalewski"'
Autor:
Hamdah Shafqat-Abbasi, Jacob M Kowalewski, Alexa Kiss, Xiaowei Gong, Pablo Hernandez-Varas, Ulrich Berge, Mehrdad Jafari-Mamaghani, John G Lock, Staffan Strömblad
Publikováno v:
eLife, Vol 5 (2016)
Mesenchymal (lamellipodial) migration is heterogeneous, although whether this reflects progressive variability or discrete, 'switchable' migration modalities, remains unclear. We present an analytical toolbox, based on quantitative single-cell imagin
Externí odkaz:
https://doaj.org/article/aaf754e3057d48ffaa4e2c52ae0bf92a
Autor:
Jacob M Kowalewski, Hamdah Shafqat-Abbasi, Mehrdad Jafari-Mamaghani, Bereket Endrias Ganebo, Xiaowei Gong, Staffan Strömblad, John G Lock
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135204 (2015)
Cell migration is heavily interconnected with plasma membrane protrusion and retraction (collectively termed "membrane dynamics"). This makes it difficult to distinguish regulatory mechanisms that differentially influence migration and membrane dynam
Externí odkaz:
https://doaj.org/article/615fb33eb9b144b196d08ccd25d0fe8c
Autor:
Marianne Renner, Christian Giaume, Amulya Nidhi Shrivastava, Antoine Triller, Jacob M. Kowalewski, Luc Bousset, Ronald Melki, Annette Koulakoff
Publikováno v:
Glia. 61:1673-1686
β-Amyloid (Aβ) oligomers initiate synaptotoxicity following their interaction with the plasma membrane. Several proteins including metabotropic glutamate type 5 receptors (mGluR5s) contribute to this process. We observed an overexpression of mGluR5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddb327b9afc5830eeacbd55b359a6fc2
https://doi.org/10.1002/glia.22548
https://doi.org/10.1002/glia.22548
Autor:
Jacob M. Kowalewski, Helene Andersson Svahn, Göran Stemme, Susanna Rydholm, Hjalmar Brismar, Thomas Frisk
Publikováno v:
Biomedical Microdevices. 10:555-560
We present the first microfabricated microfluidic devices designed specifically for studies of primary cilium mediated cellular response to dynamic flow. The primary cilium functions as a mechano-sensor in renal tubular epithelium, sensing the extrac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0d4fb317e5160738b1046e20adaaee8
https://doi.org/10.1007/s10544-008-9165-8
https://doi.org/10.1007/s10544-008-9165-8
Autor:
Ulrich Berge, Staffan Strömblad, Hamdah Shafqat-Abbasi, Mehrdad Jafari-Mamaghani, Jacob M. Kowalewski, Alexa Kiss, John G. Lock, Pablo Hernández-Varas, Xiaowei Gong
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3289c64fa223401469149bc2c137bdc7
https://doi.org/10.7554/elife.11384.037
https://doi.org/10.7554/elife.11384.037
Autor:
Hamdah Shafqat-Abbasi, Staffan Strömblad, Jacob M. Kowalewski, John G. Lock, Alexa Kiss, Xiaowei Gong
Publikováno v:
Integrative biology : quantitative biosciences from nano to macro. 7(10)
Talin is a key cell–matrix adhesion component with a central role in regulating adhesion complex maturation, and thereby various cellular properties including adhesion and migration. However, knockdown studies have produced inconsistent findings re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6d24ce7cfb016e09b2454755a0ef3d3
https://pubmed.ncbi.nlm.nih.gov/26000342
https://pubmed.ncbi.nlm.nih.gov/26000342
Autor:
Staffan Strömblad, Bereket Endrias Ganebo, Hamdah Shafqat-Abbasi, Mehrdad Jafari-Mamaghani, John G. Lock, Jacob M. Kowalewski, Xiaowei Gong
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135204 (2015)
PLoS ONE
PLoS ONE
Cell migration is heavily interconnected with plasma membrane protrusion and retraction (collectively termed "membrane dynamics"). This makes it difficult to distinguish regulatory mechanisms that differentially influence migration and membrane dynam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a550f58873215a62ce6d0f37fb3878e6
http://europepmc.org/articles/PMC4527765?pdf=render
http://europepmc.org/articles/PMC4527765?pdf=render
Autor:
Yajuan Liu, Zhilun Li, Staffan Strömblad, John G. Lock, Hongquan Zhang, Jacob M. Kowalewski, Helene Olofsson, Steffen Teller
Publikováno v:
Molecular Biology of the Cell
This article presents a novel mechanism deployed by cells to tune cell adhesion levels through the autoinhibitory regulation of integrin adhesion involving the activation of PAK4.
Cell-to-extracellular matrix adhesion is regulated by a multitude
Cell-to-extracellular matrix adhesion is regulated by a multitude
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2b220b9a6506e2599c9c7abd27e8ef2
https://pubmed.ncbi.nlm.nih.gov/20719960
https://pubmed.ncbi.nlm.nih.gov/20719960
Autor:
Thomas Frisk, Padideh Kamali-Zare, Jacob M. Kowalewski, Susanna Rydholm, Hjalmar Brismar, Gordon Zwartz
Publikováno v:
American journal of physiology. Renal physiology. 298(5)
The primary cilium is a ubiquitous organelle present on most mammalian cells. Malfunction of the organelle has been associated with various pathological disorders, many of which lead to cystic disorders in liver, pancreas, and kidney. Primary cilia h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65af0e5d91ea9817432fc830a63ca9e2
https://pubmed.ncbi.nlm.nih.gov/20147369
https://pubmed.ncbi.nlm.nih.gov/20147369
Autor:
Marina Zelenina, Michael Brines, Ulf Andersson, Hjalmar Brismar, Anita Aperia, Yutong Song, Jacob M. Kowalewski, Anthony Cerami, Eli Gunnarson
Disturbed brain water homeostasis with swelling of astroglial cells is a common complication in stroke, trauma, and meningitis and is considered to be a major cause of permanent brain damage. Astroglial cells possess the water channel aquaporin 4 (AQ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ac523d3ae273001ec645d7b91d52471
https://europepmc.org/articles/PMC2629445/
https://europepmc.org/articles/PMC2629445/