Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jacob Kohlmeier"'
Autor:
Moriah P. Bellissimo, Candace C. Fleischer, David A. Reiter, Amy M. Goss, Lei Zhou, Matthew Ryan Smith, Jacob Kohlmeier, Rabindra Tirouvanziam, Phong H. Tran, Li Hao, Benjamin H. Crain, Greg D. Wells, Dean P. Jones, Thomas R. Ziegler, Jessica A. Alvarez
Publikováno v:
Nutrition & Metabolism, Vol 19, Iss 1, Pp 1-11 (2022)
Abstract Background Adiposity and mitochondrial dysfunction are related factors contributing to metabolic disease development. This pilot study examined whether in vivo and ex vivo indices of mitochondrial metabolism were differentially associated wi
Externí odkaz:
https://doaj.org/article/b40d157947a94ccc8a4b7cd19aa56fe5
Publikováno v:
The Journal of Immunology. 194:64.1-64.1
Acting as sentinels capable of quickly organizing a secondary immune response upon pathogen challenge, resident memory CD8 T (TRM) populations are initially primed by microenvironment cues and APC licensing following acute infection of peripheral tis
Autor:
Alison Swaims, Richard Haaland, Tammy Evans-Strickfaden, Lisa Haadad, Anadi Sheth, L. Lupo, Sarah Cordes, Alfredo Aguirre, Kathryn Lupoli, Cheng-Yen Chen, Igho Ofotokun, Jacob Kohlmeier, Clyde Hart
Publikováno v:
The Journal of Immunology. 194:65.21-65.21
The Female Genital Tract (FGT) provides a means of entry to opportunistic infections, including HIV, yet immune cell populations at this mucosal surface are poorly defined. We initiated a study of 20 healthy women to characterize resident T cell popu
Publikováno v:
The Journal of Immunology. 192:134.9-134.9
Microenvironment cues regulating the establishment and maintenance of a pathogen-specific resident memory T (TRM) cell population in the lung parenchyma and airways are poorly understood. We show that local inflammation is sufficient to “pull” sy
Publikováno v:
The Journal of Immunology. 190:189.4-189.4
Respiratory viral infections, including parainfluenza virus (PIV), are a significant cause of illness and death worldwide, especially among young children and the elderly. Understanding the immune response to these viruses is important for reducing p
Publikováno v:
The Journal of Immunology. 190:171.20-171.20
Vaccines have long served as a boon for the general population, yet recent inadequacies and global outbreaks of novel subtypes of influenza have given pause to the vaccine community, highlighting the need for new vaccine strategies. Several studies h
Autor:
Alison Swaims, Richard Haaland, Davis Lupo, Tammy Evans-Strickfaden, Jacob Kohlmeier, Lisa Haddad, Clyde Hart
Publikováno v:
The Journal of Immunology. 190:210.2-210.2
Current HIV sexual acquisition models for women posit that cell-free virus is carried into genital tissues by antigen presenting cells in the mucosa and that virus also penetrates the mucosa through microabrasions. The potential for genital mucosal i
Autor:
Georgia Perona-Wright, Jacob Kohlmeier, Katja Mohrs, Tres Cookenham, David Woodland, Markus Mohrs
Publikováno v:
The Journal of Immunology. 186:150.2-150.2
Cytokines are soluble signaling molecules that orchestrate immune responses, regulating both immune protection and immunopathology. T cell differentiation is characterized by distinctive changes in cytokine production, but less is known about concomi
Autor:
Lisa Connor, Lynn Ryan, Jacob Kohlmeier, Tres Cookenham, Alan Roberts, Adam Quinn, David Woodland
Publikováno v:
The Journal of Immunology. 186:104.4-104.4
Respiratory virus infections are a major health problem in the elderly. This is due to declining immune responsiveness in the elderly and the development of CD8+ T cell clonal expansions (TCE) that perturb the memory T cell pool. We recently showed t
Autor:
Jacob Kohlmeier, William Reiley, Georgia Perona-Wright, Michael Freeman, Yager Eric, Lisa Connor, Erik Brincks, Tres Cookenham, Alan Roberts, Claire Burkum, Gary Winslow, Marcia Blackman, Markus Mohrs, David Woodland
Publikováno v:
The Journal of Immunology. 186:150.3-150.3
The development of T cell memory from naïve precursors is a complex process influenced by molecular cues received during T cell activation and differentiation. In the present study, we describe a novel role for the chemokine receptors CCR5 and CXCR