Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jacob Jaffe"'
Autor:
Jacob Jaffe
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e07d36c619a5563c834d2eed681e1210
https://doi.org/10.2139/ssrn.4180688
https://doi.org/10.2139/ssrn.4180688
Autor:
Jacob Jaffe
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8ac3b3d08fdaba3dd370cccedc6b5fd
https://doi.org/10.2139/ssrn.4082224
https://doi.org/10.2139/ssrn.4082224
Publikováno v:
Journal of Statistical Physics
The effect of a mutation on the organism often depends on what other mutations are already present in its genome. Geneticists refer to such mutational interactions as epistasis. Pairwise epistatic effects have been recognized for over a century, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b3502e07275060fdeba5cfea975e8c6
http://europepmc.org/articles/PMC5986866
http://europepmc.org/articles/PMC5986866
Autor:
Jacob Jaffe, Yan Wang, HoMan Chan, Jinghui Zhang, Roberts Huether, Gregory Kryukov, Jordan Taylor, Min Hu, Nathan Englund, Feng Yan, Zhaofu Wang, Lei Wei, Jing Ma, John Easton, William R. Sellers, Nicholas Keen, Jun Liu, Charles Mullighan, Steven Carr, James Downing, Levi Garraway, Frank Stegmeier
Publikováno v:
Cancer Research. 73:PR01-PR01
Epigenetic dysregulation is an emerging hallmark of cancers, and the identification of recurrent somatic mutations in chromatin modifying enzymes implies a causal role for altered chromatin states in tumorigenesis. While the genomic characterization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d389724640f69401a06aadddb7e8e43b
https://doi.org/10.1158/1538-7445.cec13-pr01
https://doi.org/10.1158/1538-7445.cec13-pr01
Publikováno v:
Journal of Colloid and Interface Science. 51:239-244
The monolayer approach has been used to study the interaction lipid-polypeptide. The lipid (DL-α-lecithin dipalmitoyl, phosphatidyl serine) was spread at the air-water interface; the polypeptides (poly-L-glutamic acid, poly-L-aspartic acid, poly-L-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3dae2d7faf464267acd1c82b6760cf13
https://doi.org/10.1016/0021-9797(75)90109-5
https://doi.org/10.1016/0021-9797(75)90109-5
Publikováno v:
Journal of Colloid and Interface Science. 56:360-364
A new method is described to demonstrate conformational changes in oligopeptide monolayers. A probe (2- p -toluidinylnaphthalene-6-sulfonate) which fluoresces strongly in an hydrophobic environment, is adsorbed on the oligopeptide monolayer. Fluoresc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed54815b52a88ffb17378992e0b140c9
https://doi.org/10.1016/0021-9797(76)90262-9
https://doi.org/10.1016/0021-9797(76)90262-9
Publikováno v:
Journal of Colloid and Interface Science. 49:433-441
A change of conformation of macromolecules has been investigated at the air-water interface. The model chosen is a copolypeptide of glutamic acid and methyl glutamate. The modification of the conformation of the copolypeptide is induced by changing t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8f11815ccbcf2b8b873fb01624c98c5
https://doi.org/10.1016/0021-9797(74)90389-0
https://doi.org/10.1016/0021-9797(74)90389-0
Autor:
R. De Coene, Jacob Jaffe
Publikováno v:
Journal of Polymer Science. 23:665-682
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9da3f74f3e927c41f4f914aea17b9ec0
https://doi.org/10.1002/pol.1957.1202310411
https://doi.org/10.1002/pol.1957.1202310411
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure. 207:11-17
The possibility of an α-helix-coil transition of the poly-γ-methyl- l -glutamate spread at the air-water interface has been investigated. The helical conformation of this polypeptide has been shown to exist in the solid film removed from an aqueous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1613105a39eca9565b45b5ab75cbe1d8
https://doi.org/10.1016/0005-2795(70)90132-7
https://doi.org/10.1016/0005-2795(70)90132-7
Publikováno v:
Journal de Chimie Physique. 64:499-505
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21d3b6115bb1665871182e6f3202d301
https://doi.org/10.1051/jcp/1967640499
https://doi.org/10.1051/jcp/1967640499