A fully implantable pacemaker for the mouse: from battery to wireless power.

Autor: Jacob I Laughner, Scott B Marrus, Erik R Zellmer, Carla J Weinheimer, Matthew R MacEwan, Sophia X Cui, Jeanne M Nerbonne, Igor R Efimov

Publikováno v: PLoS ONE, Vol 8, Iss 10, p e76291 (2013)

Animal models have become a popular platform for the investigation of the molecular and systemic mechanisms of pathological cardiovascular physiology. Chronic pacing studies with implantable pacemakers in large animals have led to useful models of he

Externí odkaz: https://doaj.org/article/8de29fd18ad04bef9ccb1fdbc7c49032

Local catheter impedance drop during pulmonary vein isolation predicts acute conduction block in patients with paroxysmal atrial fibrillation: initial results of the LOCALIZE clinical trial

Autor: Josselin Duchateau, Pierre Jaïs, Elizabeth Duffy, Ewen Shepherd, Armin Luik, Pablo Ramos, Jacob I. Laughner, Waqas Ullah, Arthur M. Yue, Moloy Das, Ignacio García-Bolao, Matthew S. Sulkin, Tobias Oesterlein, Christian Meyer

Publikováno v: Europace

Aims Radiofrequency ablation creates irreversible cardiac damage through resistive heating and this temperature change results in a generator impedance drop. Evaluation of a novel local impedance (LI) technology measured exclusively at the tip of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::708906254c7fb7f247e6e767ce36cb77
http://europepmc.org/articles/PMC8286855

Time-Averaged Wavefront Analysis Demonstrates Preferential Pathways of Atrial Fibrillation, Predicting Pulmonary Vein Isolation Acute Response

Autor: Mark D O'Neill, Jaswinder Gill, Reza Razavi, Petr Neuzil, Christopher A. Rinaldi, Matthew Wright, Nicholas Child, John Whitaker, Peter Taggart, Steven Williams, Iain Sim, Caroline H. Roney, Richard H. Clayton, Allan C. Shuros, Bradley Porter, Steven A. Niederer, Jacob I. Laughner

Publikováno v: Frontiers in Physiology
Frontiers in Physiology, Vol 12 (2021)

Electrical activation during atrial fibrillation (AF) appears chaotic and disorganised, which impedes characterisation of the underlying substrate and treatment planning. While globally chaotic, there may be local preferential activation pathways tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39a6a9089179c7db1721abb3171b0436
https://pubmed.ncbi.nlm.nih.gov/34646149

1319Local impedance on a force sensing catheter predicts volumetric lesion temperature changes

Autor: J Hamann, L Lehn, A Gams, K Garrott, Jacob I. Laughner, S Gutbrod

Publikováno v: EP Europace. 22

Funding Acknowledgements Study was funded by Boston Scientific The effective delivery of RF energy is dependent on transmural tissue heating, with irreversible tissue necrosis occurring at a tissue temperature ≥ 50°C. While multi-input lesion inde

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f1702bcc4085dd619c517695c0361f95
https://doi.org/10.1093/europace/euaa162.248

Unraveling the Underlying Arrhythmia Mechanism in Persistent Atrial Fibrillation

Autor: Steven A. Niederer, Tom Jackson, Allan C. Shuros, Reza Razavi, Jan Petru, Richard H. Clayton, Caroline R. Roney, Jacob I. Laughner, Petr Neuzil, Christopher A. Rinaldi, Matthew Wright, Bradley Porter, Julian Bostock, Nicholas Child, Peter Taggart, Jaswinder Gill

Publikováno v: Child, N, Clayton, R H, Roney, C H, Laughner, J I, Shuros, A, Neuzil, P, Petru, J, Jackson, T, Porter, B, Bostock, J, Niederer, S A, Razavi, R S, Rinaldi, C A, Taggart, P, Wright, M J & Gill, J 2018, ' Unraveling the Underlying Arrhythmia Mechanism in Persistent Atrial Fibrillation : Results From the STARLIGHT Study ', Circulation. Arrhythmia and electrophysiology, vol. 11, no. 6, pp. e005897 . https://doi.org/10.1161/CIRCEP.117.005897

Background: The mechanisms that initiate and sustain persistent atrial fibrillation are not well characterized. Ablation results remain significantly worse than in paroxysmal atrial fibrillation in which the mechanism is better understood and subsequ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81ae407d54dd41fe4446e4f19e76eff8
https://doi.org/10.1161/circep.117.005897