Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Jacob Helm"'
Autor:
KISCH B
Publikováno v:
Wiener medizinische Wochenschrift (1946) [Wien Med Wochenschr] 1954 Sep 04; Vol. 104 (36-37), pp. 756.
Autor:
Stefan Hauser, Jacob Helm, Melanie Kraft, Milena Korneck, Jeannette Hübener-Schmid, Ludger Schöls
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 99-108 (2022)
Spinocerebellar ataxia type 3 (SCA3) is caused by an expanded polyglutamine stretch in ataxin-3. While wild-type ataxin-3 has important functions, e.g., as a deubiquitinase, downregulation of mutant ataxin-3 is likely to slow down the course of this
Externí odkaz:
https://doaj.org/article/2ab37f41b1964049ad667cde540cb1f5
Publikováno v:
Pharmaceutics, Vol 14, Iss 8, p 1708 (2022)
Antisense oligonucleotides (ASOs) are single-stranded nucleic acid strings that can be used to selectively modify protein synthesis by binding complementary (pre-)mRNA sequences. By specific arrangements of DNA and RNA into a chain of nucleic acids a
Externí odkaz:
https://doaj.org/article/1330c15daafc47f095690e8dbae0c6ba
Autor:
Jacob, Helm
Publikováno v:
Wiener medizinische Wochenschrift (1946). 104(36-37)
Publikováno v:
Pharmaceutics 14(8), 1708 (2022). doi:10.3390/pharmaceutics14081708 special issue: "Oligonucleotides and Nucleic-Acid-Based Strategies to Address Therapeutic Challenges: From the Bench to the Bedside"
Antisense oligonucleotides (ASOs) are single-stranded nucleic acid strings that can be used to selectively modify protein synthesis by binding complementary (pre-)mRNA sequences. By specific arrangements of DNA and RNA into a chain of nucleic acids a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7d8ef8c43165dbbd13247f426816df45
https://pub.dzne.de/record/165126
https://pub.dzne.de/record/165126
Autor:
Mahkameh Abeditashi, Katherine J. Robinson, Jacob Helm, Thorsten Schmidt, Olaf Riess, Jonasz J. Weber, Zinah Wassouf, Stefan Hauser, Ludger Schöls, Jana Schmidt, Maxinne Watchon, Angela S. Laird, Priscila Pereira Sena, Jeannette Hübener-Schmid
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America 118(47), e2025810118 (2021). doi:10.1073/pnas.2025810118
Aberrant O-GlcNAcylation, a protein posttranslational modification defined by the O-linked attachment of the monosaccharide N-acetylglucosamine (O-GlcNAc), has been implicated in neurodegenerative diseases. However, although many neuronal proteins ar
Autor:
Priscila, Pereira Sena, Jonasz J, Weber, Maxinne, Watchon, Katherine J, Robinson, Zinah, Wassouf, Stefan, Hauser, Jacob, Helm, Mahkameh, Abeditashi, Jana, Schmidt, Jeannette, Hübener-Schmid, Ludger, Schöls, Angela S, Laird, Olaf, Riess, Thorsten, Schmidt
Publikováno v:
Proc Natl Acad Sci U S A
Aberrant O-GlcNAcylation, a protein posttranslational modification defined by the O-linked attachment of the monosaccharide N-acetylglucosamine (O-GlcNAc), has been implicated in neurodegenerative diseases. However, although many neuronal proteins ar
Autor:
Stefan Hauser, Jacob Helm, Melanie Kraft, Milena Korneck, Jeannette Hübener-Schmid, Ludger Schöls
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy / Nucleic Acids 27, 99-108 (2022). doi:10.1016/j.omtn.2021.11.015
Molecular Therapy: Nucleic Acids, Vol 27, Iss, Pp 99-108 (2022)
Molecular Therapy / Nucleic Acids 27, 99-108 (2022). doi:10.1016/j.omtn.2021.11.015
Molecular Therapy: Nucleic Acids, Vol 27, Iss, Pp 99-108 (2022)
Spinocerebellar ataxia type 3 (SCA3) is caused by an expanded polyglutamine stretch in ataxin-3. While wild-type ataxin-3 has important functions, e.g., as a deubiquitinase, downregulation of mutant ataxin-3 is likely to slow down the course of this
Autor:
Michael Brorsen, Jacob Helm-Petersen
Publikováno v:
Brorsen, M & Helm-Petersen, J 1998, On the Reflection of Short-Crested Waves in Numerical Models . in Proceedings from 26th International Conference on Coastal Engineering, Copenhagen, 1998 . pp. 394-407, On the Reflection of Short-Crested Waves in Numerical Models, 19/05/2010 .
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83f2ca2d4d20f6d6191fa501977cbcd5
https://vbn.aau.dk/da/publications/0930b0f0-8095-11db-8b97-000ea68e967b
https://vbn.aau.dk/da/publications/0930b0f0-8095-11db-8b97-000ea68e967b